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Newly discovered angiogenesis inhibitors and their mechanisms of action
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scholarly article
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PubMed
title
Newly discovered angiogenesis inhibitors and their mechanisms of action
(English)
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main subject
angiogenesis inhibitor
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based on heuristic
inferred from title
author name string
Ze-hong Miao
series ordinal
1
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stated in
Crossref
Jian-ming Feng
series ordinal
2
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stated in
Crossref
Jian Ding
series ordinal
3
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stated in
Crossref
language of work or name
English
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stated in
PubMed
publication date
September 2012
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stated in
PubMed
published in
Acta Pharmacologica Sinica
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PubMed
volume
33
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stated in
PubMed
issue
9
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stated in
PubMed
page(s)
1103-11
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PubMed
cites work
Increased accumulation of hypoxia-inducible factor-1α with reduced transcriptional activity mediates the antitumor effect of triptolide
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Modes of resistance to anti-angiogenic therapy
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C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation
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AL3810, a multi-tyrosine kinase inhibitor, exhibits potent anti-angiogenic and anti-tumour activity via targeting VEGFR, FGFR and PDGFR.
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Triptolide: structural modifications, structure-activity relationships, bioactivities, clinical development and mechanisms
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c-Jun protects hypoxia-inducible factor-1alpha from degradation via its oxygen-dependent degradation domain in a nontranscriptional manner
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BB, a new EGFR inhibitor, exhibits prominent anti-angiogenesis and antitumor activities
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MFTZ-1 reduces constitutive and inducible HIF-1α accumulation and VEGF secretion independent of its topoisomerase II inhibition.
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Angiogenesis and anti-angiogenic molecularly targeted therapies in malignant gliomas
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PubMed Central
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28 September 2017
Anti-angiogenic and vascular disrupting effects of C9, a new microtubule-depolymerizing agent
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28 September 2017
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The marine-derived oligosaccharide sulfate (MdOS), a novel multiple tyrosine kinase inhibitor, combats tumor angiogenesis both in vitro and in vivo
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28 September 2017
Quercetin suppresses hypoxia-induced accumulation of hypoxia-inducible factor-1alpha (HIF-1alpha) through inhibiting protein synthesis
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28 September 2017
Biology of HIF-1alpha
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PubMed Central
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28 September 2017
Structural modification of an angiogenesis inhibitor discovered from traditional Chinese medicine and a structure-activity relationship study
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PubMed Central
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28 September 2017
MFTZ-1, an actinomycetes subspecies derived antitumor macrolide, functions as a novel topoisomerase II poison
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PubMed Central
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28 September 2017
Philinopside E, a new sulfated saponin from sea cucumber, blocks the interaction between kinase insert domain-containing receptor (KDR) and alphavbeta3 integrin via binding to the extracellular domain of KDR.
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PubMed Central
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28 September 2017
Angiogenesis in cancer: molecular mechanisms, clinical impact
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PubMed Central
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28 September 2017
Oligomannurarate sulfate, a novel heparanase inhibitor simultaneously targeting basic fibroblast growth factor, combats tumor angiogenesis and metastasis
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PubMed Central
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28 September 2017
Grateloupia longifolia polysaccharide inhibits angiogenesis by downregulating tissue factor expression in HMEC-1 endothelial cells
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PubMed Central
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28 September 2017
TKI-31 inhibits angiogenesis by combined suppression signaling pathway of VEGFR2 and PDGFRbeta
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PubMed Central
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28 September 2017
The hypoxia-inducible-factor hydroxylases bring fresh air into hypoxia signalling
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PubMed Central
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28 September 2017
Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.
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PubMed Central
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28 September 2017
In vitro pharmacological characterization of TKI-28, a broad-spectrum tyrosine kinase inhibitor with anti-tumor and anti-angiogenic effects
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PubMed Central
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28 September 2017
Transcription factor c-Jun activation represses mdr-1 gene expression.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116
retrieved
28 September 2017
Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116
retrieved
28 September 2017
Quercetin, a dietary-derived flavonoid, possesses antiangiogenic potential
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116
retrieved
28 September 2017
Antiangiogenic potential of 10-hydroxycamptothecin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116
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28 September 2017
Anti-angiogenic effects of Shiraiachrome A, a compound isolated from a Chinese folk medicine used to treat rheumatoid arthritis
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4003116
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31 May 2018
The scientific contributions of M. Judah Folkman to cancer research.
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21 January 2018
Antiangiogenic activity of 11,11'-dideoxyverticillin, a natural product isolated from the fungus Shiraia bambusicola.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FAPS.2012.97
retrieved
21 January 2018
Philinopside A, a novel marine-derived compound possessing dual anti-angiogenic and anti-tumor effects
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FAPS.2012.97
retrieved
21 January 2018
Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FAPS.2012.97
retrieved
21 January 2018
Pseudolarix acid B, a new tubulin-binding agent, inhibits angiogenesis by interacting with a novel binding site on tubulin.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FAPS.2012.97
retrieved
21 January 2018
E-3810 is a potent dual inhibitor of VEGFR and FGFR that exerts antitumor activity in multiple preclinical models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1038%2FAPS.2012.97
retrieved
21 January 2018
Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22922347
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1038/APS.2012.97
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Dimensions Publication ID
1036165786
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PMCID
4003116
1 reference
stated in
PubMed
PubMed ID
22922347
1 reference
stated in
PubMed
ResearchGate publication ID
230741300
0 references
Springer Nature article ID
10.1038/aps.2012.97
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