(Q54319778)

27 May 2018

title

Pseudolaric acid B-driven phosphorylation of c-Jun impairs its role in stabilizing HIF-1alpha: a novel function-converter model. (English)

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27 May 2018

1 reference

Bing Yu

1

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27 May 2018

Mei-Hong Li

2

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27 May 2018

Wei Wang

3

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27 May 2018

Ying-Qing Wang

4

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27 May 2018

Yi Jiang

5

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27 May 2018

Sheng-Ping Yang

6

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27 May 2018

Jian-Min Yue

7

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27 May 2018

Jian Ding

8

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27 May 2018

Ze-Hong Miao

9

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27 May 2018

publication date

10 March 2012

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27 May 2018

Journal of Molecular Medicine

published in

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27 May 2018

volume

90

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27 May 2018

issue

8

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27 May 2018

page(s)

971-981

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27 May 2018

Hypoxic regulation of metastasis via hypoxia-inducible factors

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Biology of HIF-1alpha

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Biochemical purification and pharmacological inhibition of a mammalian prolyl hydroxylase acting on hypoxia-inducible factor

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The von Hippel-Lindau tumour suppressor protein: O2 sensing and cancer

21 January 2018

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Jab1 interacts directly with HIF-1alpha and regulates its stability

21 January 2018

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OS-9 interacts with hypoxia-inducible factor 1alpha and prolyl hydroxylases to promote oxygen-dependent degradation of HIF-1alpha

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The p14ARF tumor suppressor protein facilitates nucleolar sequestration of hypoxia-inducible factor-1alpha (HIF-1alpha ) and inhibits HIF-1-mediated transcription

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21 January 2018

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AP-1: a double-edged sword in tumorigenesis

21 January 2018

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c-Jun protects hypoxia-inducible factor-1alpha from degradation via its oxygen-dependent degradation domain in a nontranscriptional manner

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21 January 2018

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Pseudolaric acid B, a novel microtubule-destabilizing agent that circumvents multidrug resistance phenotype and exhibits antitumor activity in vivo.

21 January 2018

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N-benzyl-5-phenyl-1H-pyrazole-3-carboxamide promotes vascular endothelial cell angiogenesis and migration in the absence of serum and FGF-2

21 January 2018

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ATF1 phosphorylation by the ERK MAPK pathway is required for epidermal growth factor-induced c-jun expression

21 January 2018

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A reinvestigation of the multisite phosphorylation of the transcription factor c-Jun

21 January 2018

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Reversal of P-glycoprotein-mediated multidrug resistance in cancer cells by the c-Jun NH2-terminal kinase

21 January 2018

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c-Jun NH2-terminal kinase activation contributes to hypoxia-inducible factor 1alpha-dependent P-glycoprotein expression in hypoxia

21 January 2018

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PO(2)-dependent differential regulation of multidrug resistance 1 gene expression by the c-Jun NH2-terminal kinase pathway

21 January 2018

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Amino-terminal phosphorylation of c-Jun regulates stress-induced apoptosis and cellular proliferation

21 January 2018

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Functions of c-Jun in liver and heart development

21 January 2018

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c-fos regulates neuronal excitability and survival

21 January 2018

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Survival of cancer cells is maintained by EGFR independent of its kinase activity

21 January 2018

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Kinase-dead BRAF and oncogenic RAS cooperate to drive tumor progression through CRAF

21 January 2018

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Interaction between UV-damaged DNA binding activity proteins and the c-Abl tyrosine kinase

21 January 2018

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Pseudolaric acid B suppresses T lymphocyte activation through inhibition of NF-kappaB signaling pathway and p38 phosphorylation.

21 January 2018

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Structural modification of an angiogenesis inhibitor discovered from traditional Chinese medicine and a structure-activity relationship study

21 January 2018

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Total synthesis of (-)-pseudolaric acid B

21 January 2018

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Herbal diterpenoids induce growth arrest and apoptosis in colon cancer cells with increased expression of the nonsteroidal anti-inflammatory drug-activated gene.

21 January 2018

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Cytotoxicity, apoptosis induction and downregulation of MDR-1 expression by the anti-topoisomerase II agent, salvicine, in multidrug-resistant tumor cells

21 January 2018

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Pseudolaric acid B inhibits angiogenesis and reduces hypoxia-inducible factor 1alpha by promoting proteasome-mediated degradation

21 January 2018

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12 December 2020

Involvement of hypoxia-inducible factor-1-alpha in multidrug resistance induced by hypoxia in HepG2 cells.

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12 December 2020

Essential roles of PI(3)K-p110beta in cell growth, metabolism and tumorigenesis

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Transcription factor c-Jun activation represses mdr-1 gene expression.

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MDR-1 gene expression is a minor factor in determining the multidrug resistance phenotype of MCF7/ADR and KB-V1 cells

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10.1007/S00109-012-0865-4

Identifiers

DOI

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27 May 2018

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27 May 2018