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Mitochondrial proteostasis in the control of aging and longevity
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PubMed
title
Mitochondrial proteostasis in the control of aging and longevity
(English)
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main subject
mitochondrion
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inferred from title
author
Heinrich Jasper
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2
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Heinrich Jasper
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Crossref
author name string
Martin Borch Jensen
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1
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language of work or name
English
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PubMed
publication date
5 August 2014
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published in
Cell Metabolism
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PubMed
volume
20
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PubMed
issue
2
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stated in
PubMed
page(s)
214-25
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PubMed
cites work
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YME1L controls the accumulation of respiratory chain subunits and is required for apoptotic resistance, cristae morphogenesis, and cell proliferation
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21 March 2017
Aging as an event of proteostasis collapse
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21 March 2017
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
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PubMed Central
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21 March 2017
Sir2 mediates longevity in the fly through a pathway related to calorie restriction
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PubMed Central
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21 March 2017
Premature ageing in mice expressing defective mitochondrial DNA polymerase
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Complementary signaling pathways regulate the unfolded protein response and are required for C. elegans development
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Surveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein Response
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Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2
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21 March 2017
A mitochondrial superoxide signal triggers increased longevity in Caenorhabditis elegans
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21 March 2017
Relationship between mitochondrial electron transport chain dysfunction, development, and life extension in Caenorhabditis elegans
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Sequence and organization of the human mitochondrial genome
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Genome-wide responses to mitochondrial dysfunction
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Prohibitins regulate membrane protein degradation by the m-AAA protease in mitochondria
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Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans
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Declining NAD(+) induces a pseudohypoxic state disrupting nuclear-mitochondrial communication during aging
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21 March 2017
The sirtuin SIRT6 regulates lifespan in male mice
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Extending life span by increasing oxidative stress
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21 March 2017
Increased poly(ADP-ribose) polymerase activity in lymphoblastoid cell lines from centenarians
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An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
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Physiological roles of mitochondrial reactive oxygen species
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7 April 2017
Signal transduction by reactive oxygen species
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7 April 2017
The cell-non-autonomous nature of electron transport chain-mediated longevity
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7 April 2017
Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
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7 April 2017
Lifespan extension by conditions that inhibit translation in Caenorhabditis elegans
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7 April 2017
Opposing activities protect against age-onset proteotoxicity
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Extension of murine life span by overexpression of catalase targeted to mitochondria
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The plasticity of aging: insights from long-lived mutants
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Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration
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7 April 2017
Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor
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Activation of the mitochondrial unfolded protein response does not predict longevity in Caenorhabditis elegans
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Mitochondrial stress: balancing friend and foe.
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28 September 2017
Lifespan extension conferred by endoplasmic reticulum secretory pathway deficiency requires induction of the unfolded protein response.
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28 September 2017
SirT3 regulates the mitochondrial unfolded protein response
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28 September 2017
Stress-regulated translational attenuation adapts mitochondrial protein import through Tim17A degradation.
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Muscle mitohormesis promotes longevity via systemic repression of insulin signaling
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The accumulation of misfolded proteins in the mitochondrial matrix is sensed by PINK1 to induce PARK2/Parkin-mediated mitophagy of polarized mitochondria
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Calorie restriction and sirtuins revisited
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28 September 2017
Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide
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The NAD(+)/Sirtuin Pathway Modulates Longevity through Activation of Mitochondrial UPR and FOXO Signaling
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28 September 2017
XBP-1 is a cell-nonautonomous regulator of stress resistance and longevity
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28 September 2017
Epigenetic silencing mediates mitochondria stress-induced longevity
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Mitonuclear protein imbalance as a conserved longevity mechanism
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28 September 2017
Parkin overexpression during aging reduces proteotoxicity, alters mitochondrial dynamics, and extends lifespan
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28 September 2017
The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway
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28 September 2017
Evaluating and responding to mitochondrial dysfunction: the mitochondrial unfolded-protein response and beyond
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Mitochondrial import efficiency of ATFS-1 regulates mitochondrial UPR activation.
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28 September 2017
Impaired insulin/IGF1 signaling extends life span by promoting mitochondrial L-proline catabolism to induce a transient ROS signal
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28 September 2017
Genetic analysis of mitochondrial protein misfolding in Drosophila melanogaster
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28 September 2017
Modulation of longevity and tissue homeostasis by the Drosophila PGC-1 homolog.
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28 September 2017
Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation
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Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila
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28 September 2017
The homeobox protein CEH-23 mediates prolonged longevity in response to impaired mitochondrial electron transport chain in C. elegans
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28 September 2017
PARP-2 regulates SIRT1 expression and whole-body energy expenditure
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28 September 2017
Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity
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28 September 2017
The mitochondrial UPR - protecting organelle protein homeostasis
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28 September 2017
Insulin/IGF-1 signaling mutants reprogram ER stress response regulators to promote longevity
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The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans
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28 September 2017
Reduced IGF-1 signaling delays age-associated proteotoxicity in mice
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The HIF-1 hypoxia-inducible factor modulates lifespan in C. elegans
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28 September 2017
The coordination of nuclear and mitochondrial communication during aging and calorie restriction
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28 September 2017
Proteasomal regulation of the hypoxic response modulates aging in C. elegans
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Insulin and JNK: optimizing metabolic homeostasis and lifespan
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28 September 2017
Discovery of genes activated by the mitochondrial unfolded protein response (mtUPR) and cognate promoter elements
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28 September 2017
The chop gene contains an element for the positive regulation of the mitochondrial unfolded protein response
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28 September 2017
Ubiquitin-like protein 5 positively regulates chaperone gene expression in the mitochondrial unfolded protein response
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28 September 2017
Mitochondrial retrograde signaling
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28 September 2017
Somatic mtDNA mutations cause aging phenotypes without affecting reactive oxygen species production
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28 September 2017
Central Role for the Werner Syndrome Protein/Poly(ADP-Ribose) Polymerase 1 Complex in the Poly(ADP-Ribosyl)ation Pathway after DNA Damage
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28 September 2017
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28 September 2017
A mitochondrial specific stress response in mammalian cells
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28 September 2017
Extended longevity of Caenorhabditis elegans by knocking in extra copies of hsp70F, a homolog of mot-2 (mortalin)/mthsp70/Grp75.
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28 September 2017
Oxidative stress inhibits the mitochondrial import of preproteins and leads to their degradation
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28 September 2017
The small heat shock protein Hsp22 of Drosophila melanogaster is a mitochondrial protein displaying oligomeric organization
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28 September 2017
Interorganelle signaling is a determinant of longevity in Saccharomyces cerevisiae
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28 September 2017
Retrograde Ca2+ signaling in C2C12 skeletal myocytes in response to mitochondrial genetic and metabolic stress: a novel mode of inter-organelle crosstalk
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28 September 2017
Poly(ADP-ribose) polymerase enhances activator-dependent transcription in vitro
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28 September 2017
Molecular mechanisms underlying genotype-dependent responses to dietary restriction.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274350
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31 May 2018
SIRT1 mediates central circadian control in the SCN by a mechanism that decays with aging
1 reference
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PubMed Central
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31 May 2018
FOXO/4E-BP signaling in Drosophila muscles regulates organism-wide proteostasis during aging
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274350
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31 May 2018
Induction of nuclear respiratory factor-1 expression by an acute bout of exercise in rat muscle
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PubMed Central
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31 May 2018
Role of an energized inner membrane in mitochondrial protein import. Delta psi drives the movement of presequences
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PubMed Central
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31 May 2018
Mitochondrial development during Drosophila oogenesis: distribution, density and in situ RNA hybridizations
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PubMed Central
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31 May 2018
Sirtuins: Longevity focuses on NAD+.
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PubMed Central
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28 November 2018
Two modes of mitochondrial dysfunction lead independently to lifespan extension in Caenorhabditis elegans
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274350
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28 November 2018
Extension of Drosophila life span by RNAi of the mitochondrial respiratory chain
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stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274350
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28 November 2018
Increasing organismal healthspan by enhancing mitochondrial protein quality control.
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PubMed Central
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28 November 2018
ClpP mediates activation of a mitochondrial unfolded protein response in C. elegans
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PubMed Central
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28 November 2018
Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4274350
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28 November 2018
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly.
1 reference
stated in
PubMed Central
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28 November 2018
Compartment-specific perturbation of protein handling activates genes encoding mitochondrial chaperones
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PubMed Central
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28 November 2018
Overexpression of the small mitochondrial Hsp22 extends Drosophila life span and increases resistance to oxidative stress
1 reference
stated in
PubMed Central
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28 November 2018
Rates of behavior and aging specified by mitochondrial function during development
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PubMed Central
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28 November 2018
Mitochondrial genome content is regulated during nematode development
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PubMed Central
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28 November 2018
Mitochondrial electron transport is a key determinant of life span in Caenorhabditis elegans
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PubMed Central
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28 November 2018
UCP1 is essential for adaptive adrenergic nonshivering thermogenesis
1 reference
stated in
PubMed
reference URL
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retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Nitric oxide and mitochondrial biogenesis
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24930971
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Selective induction of mitochondrial chaperones in response to loss of the mitochondrial genome
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24930971
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
(ADP-ribose)n participates in DNA excision repair
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/24930971
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1016/J.CMET.2014.05.006
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2554128
OpenCitations bibliographic resource ID
2554128
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2554128
PMC publication ID
4274350
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2554128
PubMed publication ID
24930971
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
2554128
ResearchGate publication ID
263129684
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