(Q27013815)

language of work or name

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July 2013

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14

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PubMed

issue

7

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PubMed

page(s)

739-48

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Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

PubMed

cites work

1 reference

Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx

21 January 2018

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The endothelial glycocalyx: composition, functions, and visualization

21 January 2018

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Role of the endocytic machinery in the sorting of lysosome-associated membrane proteins

21 January 2018

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Transport of the lysosomal membrane glycoprotein lgp120 (lgp-A) to lysosomes does not require appearance on the plasma membrane

21 January 2018

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Signals for sorting of transmembrane proteins to endosomes and lysosomes

21 January 2018

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Sorting of lysosomal proteins

21 January 2018

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Vacuolar ATPases: rotary proton pumps in physiology and pathophysiology

21 January 2018

1 reference

V1 and V0 domains of the human H+-ATPase are linked by an interaction between the G and a subunits

21 January 2018

1 reference

The amino-terminal domain of the vacuolar proton-translocating ATPase a subunit controls targeting and in vivo dissociation, and the carboxyl-terminal domain affects coupling of proton transport and ATP hydrolysis.

21 January 2018

1 reference

A dileucine motif and a cluster of acidic amino acids in the second cytoplasmic domain of the batten disease-related CLN3 protein are required for efficient lysosomal targeting

21 January 2018

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Lysosome-associated protein transmembrane 4 alpha (LAPTM4 alpha) requires two tandemly arranged tyrosine-based signals for sorting to lysosomes

21 January 2018

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Two di-leucine motifs regulate trafficking of mucolipin-1 to lysosomes

21 January 2018

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Molecular and cellular basis of lysosomal transmembrane protein dysfunction

21 January 2018

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The proteome of lysosomes

21 January 2018

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Primary LAMP-2 deficiency causes X-linked vacuolar cardiomyopathy and myopathy (Danon disease).

21 January 2018

1 reference

Impaired autolysosome formation correlates with Lamp-2 depletion: role of apoptosis, autophagy, and necrosis in pancreatitis

21 January 2018

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Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches

21 January 2018

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Disturbed cholesterol traffic but normal proteolytic function in LAMP-1/LAMP-2 double-deficient fibroblasts

21 January 2018

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The lysosomal polypeptide transporter TAPL is stabilized by interaction with LAMP-1 and LAMP-2

21 January 2018

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Chaperone-mediated autophagy: a unique way to enter the lysosome world

21 January 2018

1 reference

LAMP proteins are required for fusion of lysosomes with phagosomes

21 January 2018

1 reference

Neuraminidase 1 is a negative regulator of lysosomal exocytosis

21 January 2018

1 reference

Palmitoylation-dependent association with CD63 targets the Ca2+ sensor synaptotagmin VII to lysosomes

21 January 2018

1 reference

Deficiency of the tetraspanin CD63 associated with kidney pathology but normal lysosomal function

21 January 2018

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CD63 is an essential cofactor to leukocyte recruitment by endothelial P-selectin

21 January 2018

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The tetraspanin CD63 regulates ESCRT-independent and -dependent endosomal sorting during melanogenesis

21 January 2018

1 reference

CD36: a class B scavenger receptor involved in angiogenesis, atherosclerosis, inflammation, and lipid metabolism

21 January 2018

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Lysosomal integral membrane protein II binds thrombospondin-1. Structure-function homology with the cell adhesion molecule CD36 defines a conserved recognition motif

21 January 2018

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LIMP-2 is a receptor for lysosomal mannose-6-phosphate-independent targeting of beta-glucocerebrosidase

21 January 2018

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Disease-causing mutations within the lysosomal integral membrane protein type 2 (LIMP-2) reveal the nature of binding to its ligand beta-glucocerebrosidase

21 January 2018

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A critical histidine residue within LIMP-2 mediates pH sensitive binding to its ligand β-glucocerebrosidase.

21 January 2018

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Ebola virus entry requires the cholesterol transporter Niemann-Pick C1

21 January 2018

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Scavenger receptor B2 is a cellular receptor for enterovirus 71

21 January 2018

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Identification of a human SCARB2 region that is important for enterovirus 71 binding and infection.

21 January 2018

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Human SCARB2-mediated entry and endocytosis of EV71

21 January 2018

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Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection

21 January 2018

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Ebola virus entry requires the host-programmed recognition of an intracellular receptor

21 January 2018

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Structure and properties of the vacuolar (H+)-ATPases

21 January 2018

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Regulation and isoform function of the V-ATPases

21 January 2018

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Direct recruitment of H+-ATPase from lysosomes for phagosomal acidification.

21 January 2018

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V-ATPase engagement in autophagic processes

21 January 2018

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Human SCARB2-dependent infection by coxsackievirus A7, A14, and A16 and enterovirus 71

21 January 2018

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Live imaging of neuronal degradation by microglia reveals a role for v0-ATPase a1 in phagosomal fusion in vivo

21 January 2018

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The v-ATPase V0 subunit a1 is required for a late step in synaptic vesicle exocytosis in Drosophila.

21 January 2018

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The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans

21 January 2018

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(Pro)renin receptor and vacuolar H(+)-ATPase

21 January 2018

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Scavenger receptor b2 as a receptor for hand, foot, and mouth disease and severe neurological diseases.

21 January 2018

1 reference

The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila

21 January 2018

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The vacuolar ATPase is required for physiological as well as pathological activation of the Notch receptor

21 January 2018

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mTORC1 senses lysosomal amino acids through an inside-out mechanism that requires the vacuolar H(+)-ATPase

21 January 2018

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mTOR signaling in growth control and disease

21 January 2018

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The Cl-/H+ antiporter ClC-7 is the primary chloride permeation pathway in lysosomes.

21 January 2018

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ClC-7 is a slowly voltage-gated 2Cl(-)/1H(+)-exchanger and requires Ostm1 for transport activity

21 January 2018

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Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man

21 January 2018

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Lysosomal pathology and osteopetrosis upon loss of H+-driven lysosomal Cl- accumulation

21 January 2018

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A cation counterflux supports lysosomal acidification

21 January 2018

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TPC proteins are phosphoinositide- activated sodium-selective ion channels in endosomes and lysosomes

21 January 2018

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NAADP mobilizes calcium from acidic organelles through two-pore channels

21 January 2018

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The type IV mucolipidosis-associated protein TRPML1 is an endolysosomal iron release channel

21 January 2018

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PI(3,5)P2 controls membrane trafficking by direct activation of mucolipin Ca2+ release channels in the endolysosome

21 January 2018

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Cystinosin, the protein defective in cystinosis, is a H(+)-driven lysosomal cystine transporter

21 January 2018

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LAAT-1 is the lysosomal lysine/arginine transporter that maintains amino acid homeostasis

21 January 2018

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Heptahelical protein PQLC2 is a lysosomal cationic amino acid exporter underlying the action of cysteamine in cystinosis therapy

21 January 2018

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Identification of a putative lysosomal cobalamin exporter altered in the cblF defect of vitamin B12 metabolism

21 January 2018

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Mutations in ABCD4 cause a new inborn error of vitamin B12 metabolism

21 January 2018

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Selective and ATP-dependent translocation of peptides by the homodimeric ATP binding cassette transporter TAP-like (ABCB9)

21 January 2018

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Ion flux and the function of endosomes and lysosomes: pH is just the start: the flux of ions across endosomal membranes influences endosome function not only through regulation of the luminal pH.

21 January 2018

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Organellar proteomics: turning inventories into insights

21 January 2018

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Proteomics of the lysosome

21 January 2018

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Integral and associated lysosomal membrane proteins

21 January 2018

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TM7SF1 (GPR137B): a novel lysosome integral membrane protein

21 January 2018

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NCU-G1 is a highly glycosylated integral membrane protein of the lysosome

21 January 2018

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Molecular characterisation of 'transmembrane protein 192' (TMEM192), a novel protein of the lysosomal membrane

21 January 2018

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Disrupted in renal carcinoma 2 (DIRC2), a novel transporter of the lysosomal membrane, is proteolytically processed by cathepsin L.

21 January 2018

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Specific functions of lysosomal proteases in endocytic and autophagic pathways.

21 January 2018

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Intramembrane proteolysis

21 January 2018

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Presenilin-1, Nicastrin, Amyloid Precursor Protein, and γ-Secretase Activity Are Co-localized in the Lysosomal Membrane

21 January 2018

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Signal-peptide-peptidase-like 2a (SPPL2a) is targeted to lysosomes/late endosomes by a tyrosine motif in its C-terminal tail

21 January 2018

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The intramembrane protease SPPL2a promotes B cell development and controls endosomal traffic by cleavage of the invariant chain

21 January 2018

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Analysis of the biogenesis of heparan sulfate acetyl-CoA:alpha-glucosaminide N-acetyltransferase provides insights into the mechanism underlying its complete deficiency in mucopolysaccharidosis IIIC

21 January 2018

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TRP-ML1 is a lysosomal monovalent cation channel that undergoes proteolytic cleavage

21 January 2018

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Proteolytic cleavage of the disease-related lysosomal membrane glycoprotein CLN7.

21 January 2018

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LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV.

21 January 2018

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Isolation of a novel gene underlying batten disease, CLN3

21 January 2018

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The novel neuronal ceroid lipofuscinosis gene MFSD8 encodes a putative lysosomal transporter

21 January 2018

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A novel gene encoding an integral membrane protein is mutated in nephropathic cystinosis

21 January 2018

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Identification of the gene encoding the enzyme deficient in mucopolysaccharidosis IIIC (Sanfilippo disease type C)

21 January 2018

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Mutations in TMEM76* cause mucopolysaccharidosis IIIC (Sanfilippo C syndrome)

21 January 2018

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Niemann-Pick C1 disease gene: homology to mediators of cholesterol homeostasis

21 January 2018

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Mucolipidosis type IV is caused by mutations in a gene encoding a novel transient receptor potential channel

21 January 2018

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Identification of the gene causing mucolipidosis type IV.

21 January 2018

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A new gene, encoding an anion transporter, is mutated in sialic acid storage diseases

21 January 2018

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