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The pancreas cancer microenvironment
scientific article
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1 reference
stated in
PubMed
title
The pancreas cancer microenvironment
(English)
0 references
main subject
pancreas
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author
Christine Feig
object named as
C. Feig
series ordinal
1
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Natalie Cook
object named as
N. Cook
series ordinal
5
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author name string
A. Gopinathan
series ordinal
2
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stated in
Crossref
A. Neesse
series ordinal
3
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stated in
Crossref
D. S. Chan
series ordinal
4
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stated in
Crossref
D. A. Tuveson
series ordinal
6
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stated in
Crossref
language of work or name
English
1 reference
stated in
PubMed
publication date
15 August 2012
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stated in
PubMed
published in
Clinical Cancer Research
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stated in
PubMed
volume
18
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stated in
PubMed
issue
16
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stated in
PubMed
page(s)
4266-76
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stated in
PubMed
cites work
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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes
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Enzymatic targeting of the stroma ablates physical barriers to treatment of pancreatic ductal adenocarcinoma
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CD40 agonists alter tumor stroma and show efficacy against pancreatic carcinoma in mice and humans
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Pancreatic stellate cells enhance stem cell-like phenotypes in pancreatic cancer cells
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Hyaluronan impairs vascular function and drug delivery in a mouse model of pancreatic cancer
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Pancreatic stellate cells form a niche for cancer stem cells and promote their self-renewal and invasiveness.
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28 September 2017
Gamma secretase inhibition promotes hypoxic necrosis in mouse pancreatic ductal adenocarcinoma
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28 September 2017
Recent advances in pathway-targeted cancer drug therapies emerging from cancer genome analysis
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StellaTUM: current consensus and discussion on pancreatic stellate cell research
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Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma
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Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial
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28 September 2017
Adjuvant treatment of pancreatic cancer
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28 September 2017
Retinoic acid-induced pancreatic stellate cell quiescence reduces paracrine Wnt-β-catenin signaling to slow tumor progression
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28 September 2017
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner
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28 September 2017
Analysis of the human pancreatic stellate cell secreted proteome
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28 September 2017
Stat3 and MMP7 contribute to pancreatic ductal adenocarcinoma initiation and progression.
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28 September 2017
Potential targets for pancreatic cancer immunotherapeutics
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28 September 2017
A lethally irradiated allogeneic granulocyte-macrophage colony stimulating factor-secreting tumor vaccine for pancreatic adenocarcinoma. A Phase II trial of safety, efficacy, and immune activation
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28 September 2017
Suppression of antitumor immunity by stromal cells expressing fibroblast activation protein-alpha
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28 September 2017
Hypoxia and hypoxia-inducible factors: master regulators of metastasis
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28 September 2017
Role of pancreatic stellate cells in pancreatic cancer metastasis.
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28 September 2017
Pancreatic stellate cell models for transcriptional studies of desmoplasia-associated genes.
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28 September 2017
Gemcitabine plus sorafenib in patients with advanced pancreatic cancer: a phase II trial of the University of Chicago Phase II Consortium
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28 September 2017
Tumour necrosis is a postoperative prognostic marker for pancreatic cancer patients with a high interobserver reproducibility in histological evaluation
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Gemcitabine plus bevacizumab compared with gemcitabine plus placebo in patients with advanced pancreatic cancer: phase III trial of the Cancer and Leukemia Group B (CALGB 80303).
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28 September 2017
Phase II and coagulation cascade biomarker study of bevacizumab with or without docetaxel in patients with previously treated metastatic pancreatic adenocarcinoma
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28 September 2017
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28 September 2017
Phase II study of bevacizumab with concurrent capecitabine and radiation followed by maintenance gemcitabine and bevacizumab for locally advanced pancreatic cancer: Radiation Therapy Oncology Group RTOG 0411
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28 September 2017
Organotypic culture model of pancreatic cancer demonstrates that stromal cells modulate E-cadherin, beta-catenin, and Ezrin expression in tumor cells
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28 September 2017
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28 September 2017
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28 September 2017
Hedgehog signaling is restricted to the stromal compartment during pancreatic carcinogenesis
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28 September 2017
A phase I/II study of a MUC1 peptide pulsed autologous dendritic cell vaccine as adjuvant therapy in patients with resected pancreatic and biliary tumors.
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28 September 2017
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28 September 2017
Sonic hedgehog promotes desmoplasia in pancreatic cancer
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28 September 2017
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28 September 2017
Cancer-associated stromal fibroblasts promote pancreatic tumor progression
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28 September 2017
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28 September 2017
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A randomized multi-center phase II trial of the angiogenesis inhibitor Cilengitide (EMD 121974) and gemcitabine compared with gemcitabine alone in advanced unresectable pancreatic cancer
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Immortalization of pancreatic stellate cells as an in vitro model of pancreatic fibrosis: deactivation is induced by matrigel and N-acetylcysteine
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28 September 2017
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28 September 2017
Activated Kras and Ink4a/Arf deficiency cooperate to produce metastatic pancreatic ductal adenocarcinoma
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28 September 2017
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28 September 2017
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28 September 2017
A double-blind placebo-controlled, randomised study comparing gemcitabine and marimastat with gemcitabine and placebo as first line therapy in patients with advanced pancreatic cancer
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28 September 2017
Generation of multiple angiogenesis inhibitors by human pancreatic cancer
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28 September 2017
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28 September 2017
Activation of pancreatic stellate cells in human and experimental pancreatic fibrosis
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28 September 2017
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28 September 2017
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31 May 2018
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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31 May 2018
Contribution of murine bone marrow mesenchymal stem cells to pancreas regeneration after partial pancreatectomy in mice.
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Axitinib plus gemcitabine versus placebo plus gemcitabine in patients with advanced pancreatic adenocarcinoma: a double-blind randomised phase 3 study
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Phase 2 trial of single agent Ipilimumab (anti-CTLA-4) for locally advanced or metastatic pancreatic adenocarcinoma
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Bone marrow contributes to the population of pancreatic stellate cells in mice
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Phase III trial of bevacizumab in combination with gemcitabine and erlotinib in patients with metastatic pancreatic cancer
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
The use of GEM models for experimental cancer therapeutics
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Resolution of liver cirrhosis using vitamin A-coupled liposomes to deliver siRNA against a collagen-specific chaperone
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Expression pattern and circulating levels of endostatin in patients with pancreas cancer
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Differential diagnosis of pancreatic tumors using ultrasound contrast imaging.
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Prognostic significance of HIF-1 alpha overexpression in human pancreatic cancer
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28 November 2018
Comparison of gemcitabine versus the matrix metalloproteinase inhibitor BAY 12-9566 in patients with advanced or metastatic adenocarcinoma of the pancreas: a phase III trial of the National Cancer Institute of Canada Clinical Trials Group
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Extracellular signal regulated kinases are key mediators of mitogenic signals in rat pancreatic stellate cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Identification of mediators stimulating proliferation and matrix synthesis of rat pancreatic stellate cells
1 reference
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human pancreatic adenocarcinomas: clinicopathologic and prognostic significance of matrilysin expression.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Vessel counts and vascular endothelial growth factor expression in pancreatic adenocarcinoma.
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3442232
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28 November 2018
Diagnosis and staging of pancreatic adenocarcinoma with dynamic computed tomography
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28 November 2018
Pancreatitis and the risk of pancreatic cancer. International Pancreatitis Study Group.
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28 November 2018
Enhanced expression of vascular endothelial growth factor in human pancreatic cancer correlates with local disease progression
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stat3/Socs3 Activation by IL-6 Transsignaling Promotes Progression of Pancreatic Intraepithelial Neoplasia and Development of Pancreatic Cancer
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22896693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Dynamics of the immune reaction to pancreatic cancer from inception to invasion
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22896693
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12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Pancreatic tumors show high levels of hypoxia
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22896693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Peritumoral fibroblast SPARC expression and patient outcome with resectable pancreatic adenocarcinoma
1 reference
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PubMed
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https://pubmed.ncbi.nlm.nih.gov/22896693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Hypoxia Predicts Aggressive Growth and Spontaneous Metastasis Formation from Orthotopically Grown Primary Xenografts of Human Pancreatic Cancer
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22896693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Clinicopathological significance of hypoxia-inducible factor-1alpha expression in human pancreatic carcinoma
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/22896693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Stromal SPARC expression and patient survival after chemoradiation for non-resectable pancreatic adenocarcinoma
1 reference
stated in
PubMed
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https://pubmed.ncbi.nlm.nih.gov/22896693
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1158/1078-0432.CCR-11-3114
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
680774
OpenCitations bibliographic resource ID
680774
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
680774
PMCID
3442232
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
680774
PubMed ID
22896693
1 reference
stated in
Consolidated OpenCitations Corpus – April 2017
OpenCitations bibliographic resource ID
680774
ResearchGate publication ID
230679408
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