(Q27106006)

C-1027 Chromophore (English)

5 October 2016

chemical formula

C₄₃H₄₂ClN₃O₁₃

1 reference

C-1027 Chromophore (English)

5 October 2016

canonical SMILES

CC1(C(C(C(C(O1)OC23C=CC=C2C#CC4=CC#CC3OC5=C(C=C(C=C5Cl)C(CC(=O)OCC4OC(=O)C6=CC(=CC7=C6NC(=O)C(=C)O7)OC)N)O)O)O)N(C)C)C

1 reference

C-1027 Chromophore (English)

5 October 2016

isomeric SMILES

CC1(C(C(C(C(O1)O[C@]23C=CC=C2C#C/C/4=C\C#C[C@H]3OC5=C(C=C(C=C5Cl)[C@H](CC(=O)OC[C@@H]4OC(=O)C6=CC(=CC7=C6NC(=O)C(=C)O7)OC)N)O)O)O)N(C)C)C

1 reference

Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein

C-1027 Chromophore (English)

5 October 2016

6 references

Biochemical characterization of the SgcA1 alpha-D-glucopyranosyl-1-phosphate thymidylyltransferase from the enediyne antitumor antibiotic C-1027 biosynthetic pathway and overexpression of sgcA1 in Streptomyces globisporus to improve C-1027 productio

Preliminary X-ray diffraction study of a new crystal form of C-1027-AG, the apoprotein of the macromolecular antitumor antibiotic C-1027 from Streptomyces globisporus

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027.

Improvement of the enediyne antitumor antibiotic C-1027 production by manipulating its biosynthetic pathway regulation in Streptomyces globisporus

Identifiers

InChI

InChI=1S/C43H42ClN3O13/c1-21-39(52)46-34-26(17-25(54-6)18-30(34)56-21)40(53)57-31-20-55-33(49)19-28(45)23-15-27(44)37(29(48)16-23)58-32-11-7-9-22(31)12-13-24-10-8-14-43(24,32)60-41-36(51)35(50)38(47(4)5)42(2,3)59-41/h8-10,14-18,28,31-32,35-36,38,41,48,50-51H,1,19-20,45H2,2-6H3,(H,46,52)/b22-9+/t28-,31-,32+,35?,36?,38?,41?,43+/m0/s1

1 reference

C-1027 Chromophore (English)

DGGZCXUXASNDAC-VXNBTGQKSA-N

5 October 2016

InChIKey

2 references

C-1027 Chromophore (English)

5 October 2016

ChEBI release 2020-09-01

2 references

C-1027 Chromophore (English)

matched by identifier from

5 October 2016

InChIKey

DGGZCXUXASNDAC-VXNBTGQKSA-N

ChEBI ID

3252

mapping relation type

1 reference

C-1027 Chromophore (English)

5 October 2016

1 reference

1 reference

C-1027 Chromophore (English)