(Q34088361)

30 July 2017

Manipulation of pathway regulation in Streptomyces globisporus for overproduction of the enediyne antitumor antibiotic C-1027. (English)

1 reference

DGGZCXUXASNDAC-ZDBXZSGKSA-N

30 July 2017

0 references

1 reference

Streptomyces globisporus

1 reference

inferred from

reverse claim

1 reference

1 reference

Yihua Chen

1

1 reference

30 July 2017

Min Yin

2

1 reference

30 July 2017

Geoff P Horsman

3

1 reference

30 July 2017

Shengxiong Huang

4

1 reference

30 July 2017

Ben Shen

5

1 reference

30 July 2017

16 June 2010

1 reference

full work available at URL

30 July 2017

https://www.nature.com/articles/ja201055.pdf

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1038/ja.2010.55?email=unpaywall_01@example.com

published in

The Journal of Antibiotics

1 reference

30 July 2017

63

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30 July 2017

8

1 reference

30 July 2017

482-485

1 reference

https://api.unpaywall.org/v2/10.1038/ja.2010.55?email=unpaywall_01@example.com

30 July 2017

1 reference

19 March 2024

access restriction status

open access

1 reference

inferred from online access status

exact match

https://scigraph.springernature.com/pub.10.1038/ja.2010.55

0 references

cites work

Polyketide synthase chemistry does not direct biosynthetic divergence between 9- and 10-membered enediynes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Characterization of the SgcF epoxide hydrolase supporting an (R)-vicinal diol intermediate for enediyne antitumor antibiotic C-1027 biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Production of octaketide polyenes by the calicheamicin polyketide synthase CalE8: implications for the biosynthesis of enediyne core structures

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

A free-standing condensation enzyme catalyzing ester bond formation in C-1027 biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Role of sgcR3 in positive regulation of enediyne antibiotic C-1027 production of Streptomyces globisporus C-1027

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Improving production of bioactive secondary metabolites in actinomycetes by metabolic engineering

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Biosynthesis of enediyne antitumor antibiotics

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Enediyne anticancer antibiotic lidamycin: chemistry, biology and pharmacology

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Biosynthesis of the enediyne antitumor antibiotic C-1027 involves a new branching point in chorismate metabolism

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Rapid PCR amplification of minimal enediyne polyketide synthase cassettes leads to a predictive familial classification model

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Genes for production of the enediyne antitumor antibiotic C-1027 in Streptomyces globisporus are clustered with the cagA gene that encodes the C-1027 apoprotein

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Production of the antitumor drug epirubicin (4'-epidoxorubicin) and its precursor by a genetically engineered strain of Streptomyces peucetius

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Arac/XylS family of transcriptional regulators

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

5 July 2018

The enediyne antibiotics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Analysis of Streptomyces avermitilis genes required for avermectin biosynthesis utilizing a novel integration vector

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

Sporolides A and B: structurally unprecedented halogenated macrolides from the marine actinomycete Salinispora tropica.

5 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

NovG, a DNA-binding protein acting as a positive regulator of novobiocin biosynthesis.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

A novel 4-methylideneimidazole-5-one-containing tyrosine aminomutase in enediyne antitumor antibiotic C-1027 biosynthesis

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

A genomics-guided approach for discovering and expressing cryptic metabolic pathways.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2929275

The regulator of streptomycin gene expression, StrR, of Streptomyces griseus is a DNA binding activator protein with multiple recognition sites

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20551990

12 December 2020

inferred from PubMed ID database lookup

Biosynthesis of the enediyne antitumor antibiotic C-1027

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20551990

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/JA.2010.55

1 reference

Dimensions Publication ID

30 July 2017

1015461954

0 references

Fatcat ID

release_fg2t24niwnfp5lx235lfahh3hu

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fg2t24niwnfp5lx235lfahh3hu

24 November 2022

mapped directly with Wikidata item

PMCID

2929275

1 reference

30 July 2017

1 reference