Wikidata

(Q27106127)

English

cephamycin c

chemical compound

  • (6R,7S)-3-[[(aminocarbonyl)oxy]methyl]-7alpha-[[(R)-5-amino-5-carboxy-1-oxopentyl]amino]-7-methoxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • A16886B
  • A 16886B
  • A-16886B
  • cephemimycin
  • antibiotic 842A
  • antibiotic A-16886B
  • antibiotic WS-3442C
  • antibiotic A-16886I
In more languages

Statements

mass
446.110749±0 dalton
1 reference
stated in
PubChem
PubChem CID
441084
language of work or name
English
title
cephamycin C (English)
retrieved
5 October 2016
chemical formula
C₁₆H₂₂N₄O₉S
1 reference
stated in
PubChem
PubChem CID
441084
language of work or name
English
title
cephamycin C (English)
retrieved
20 November 2016
canonical SMILES
COC1(C2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CCCC(C(=O)O)N
1 reference
stated in
PubChem
PubChem CID
441084
language of work or name
English
title
cephamycin C (English)
retrieved
20 November 2016
isomeric SMILES
CO[C@@]1([C@@H]2N(C1=O)C(=C(CS2)COC(=O)N)C(=O)O)NC(=O)CCC[C@H](C(=O)O)N
1 reference
stated in
PubChem
PubChem CID
441084
language of work or name
English
title
cephamycin C (English)
retrieved
20 November 2016
found in taxon
Streptomyces clavuligerus
37 references
stated in
Activation of Secondary Metabolite Gene Clusters in by the PimM Regulator of
stated in
Metabolic engineering of cephalosporin biosynthesis in Streptomyces clavuligerus
stated in
Draft genome sequence of Streptomyces clavuligerus NRRL 3585, a producer of diverse secondary metabolites.
stated in
Expression of ccaR, encoding the positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus, is dependent on bldG.
stated in
Dissociation of cephamycin C and clavulanic acid biosynthesis by 1,3-diaminopropane in Streptomyces clavuligerus.
stated in
Production of clavulanic acid and cephamycin C by Streptomyces clavuligerus in palm-oil medium
stated in
Early cephamycin biosynthetic genes are expressed from a polycistronic transcript in Streptomyces clavuligerus
stated in
Data set of in silico simulation for the production of clavulanic acid and cephamycin C by Streptomyces clavuligerus using a genome scale metabolic model
stated in
The two-component system CepRS regulates the cephamycin C biosynthesis in Streptomyces clavuligerus F613-1
stated in
Cephamycin C production is regulated by relA and rsh genes in Streptomyces clavuligerus ATCC27064.
stated in
An adenosine triphosphate-dependent carbamoylphosphate-3-hydroxymethylcephem O-carbamoyltransferase from Streptomyces clavuligerus
stated in
Production kinetics and stability properties of delta(L-alpha-aminoadipyl)-L-cysteinyl-D-valine synthetase from Streptomyces clavuligerus
stated in
A putative antimicrobial peptide from Hymenoptera in the megaplasmid pSCL4 of ATCC 27064 reveals a singular case of horizontal gene transfer with potential applications
stated in
The Pathway-Specific Regulator ClaR of Streptomyces clavuligerus Has a Global Effect on the Expression of Genes for Secondary Metabolism and Differentiation
stated in
Regulation of cephamycin C synthesis, aspartokinase, dihydrodipicolinic acid synthetase, and homoserine dehydrogenase by aspartic acid family amino acids in Streptomyces clavuligerus
stated in
Homologous expression of lysA encoding diaminopimelic acid (DAP) decarboxylase reveals increased antibiotic production in Streptomyces clavuligerus
stated in
An rplKDelta29-PALG-32 mutation leads to reduced expression of the regulatory genes ccaR and claR and very low transcription of the ceaS2 gene for clavulanic acid biosynthesis in Streptomyces clavuligerus
stated in
Oxygen derepresses deacetoxycephalosporin C synthase and increases the conversion of penicillin N to cephamycin C in Streptomyces clavuligerus
stated in
The claR gene of Streptomyces clavuligerus, encoding a LysR-type regulatory protein controlling clavulanic acid biosynthesis, is linked to the clavulanate-9-aldehyde reductase (car) gene.
stated in
The positive activator of cephamycin C and clavulanic acid production in Streptomyces clavuligerus is mistranslated in a bldA mutant
stated in
Mutants of Streptomyces clavuligerus with disruptions in different genes for clavulanic acid biosynthesis produce large amounts of holomycin: possible cross-regulation of two unrelated secondary metabolic pathways
stated in
Homologous expression of aspartokinase (ask) gene in Streptomyces clavuligerus and its hom-deleted mutant: effects on cephamycin C production.
stated in
Streptomyces clavuligerus relA-null mutants overproduce clavulanic acid and cephamycin C: negative regulation of secondary metabolism by (p)ppGpp.
stated in
Different proteins bind to the butyrolactone receptor protein ARE sequence located upstream of the regulatory ccaR gene of Streptomyces clavuligerus
stated in
Genes specific for the biosynthesis of clavam metabolites antipodal to clavulanic acid are clustered with the gene for clavaminate synthase 1 in Streptomyces clavuligerus
stated in
Production of cephamycin C by Streptomyces clavuligerus NT4 using solid-state fermentation.
stated in
Effect of water activity on production of beta-lactam antibiotics by Streptomyces clavuligerus in submerged culture
stated in
Incorporation of Labeled Precursors into A16886B, a Novel β-Lactam Antibiotic Produced by Streptomyces clavuligerus
stated in
5S clavam biosynthesis is controlled by an atypical two-component regulatory system in Streptomyces clavuligerus
stated in
Possible involvement of the lysine epsilon-aminotransferase gene (lat) in the expression of the genes encoding ACV synthetase (pcbAB) and isopenicillin N synthase (pcbC) in Streptomyces clavuligerus.
stated in
Characterization of DNA-binding sequences for CcaR in the cephamycin-clavulanic acid supercluster of Streptomyces clavuligerus
stated in
Enhancing effect of lysine combined with other compounds on cephamycin C production in Streptomyces clavuligerus
stated in
Cloning, characterization and heterologous expression of the aspartokinase and aspartate semialdehyde dehydrogenase genes of cephamycin C-producer Streptomyces clavuligerus
stated in
Simultaneous analysis of spatio-temporal gene expression for cephamycin biosynthesis in Streptomyces clavuligerus
stated in
Transcriptional mapping of the genes encoding the early enzymes of the cephamycin biosynthetic pathway of Streptomyces clavuligerus
stated in
Heterologous expression of Streptomyces clavuligerus ATCC 27064 cephamycin C gene cluster.
stated in
Enzymes catalyzing the early steps of clavulanic acid biosynthesis are encoded by two sets of paralogous genes in Streptomyces clavuligerus

Identifiers

Reaxys registry number
5406186
1 reference
stated in
ChEBI
ChEBI ID
3543
language of work or name
English
title
cephamycin C (English)
retrieved
5 October 2016
KEGG ID
C06566
1 reference
stated in
ChEBI
ChEBI ID
3543
language of work or name
English
title
cephamycin C (English)
retrieved
5 October 2016
 
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