(Q27293933)

Cryptophycin 1 (English)

(3S,6R,10S,13Z,16S)-10-[(3-chloro-4-methoxyphenyl)methyl]-6-methyl-3-(2-methylpropyl)-16-[(1R)-1-[(2R,3R)-3-phenyloxiran-2-yl]ethyl]-1,4-dioxa-8,11-diazacyclohexadec-13-ene-2,5,9,12-tetrone

14 October 2016

stereoisomer of

2 references

based on heuristic

inferred from InChIKey

2 references

inferred from InChIKey

2 references

inferred from InChIKey

1 reference

1 reference

1 reference

C₃₅H₄₃ClN₂O₈

1 reference

Cryptophycin 1 (English)

14 October 2016

canonical SMILES

CC1CNC(=O)C(NC(=O)C=CCC(OC(=O)C(OC1=O)CC(C)C)C(C)C2C(O2)C3=CC=CC=C3)CC4=CC(=C(C=C4)OC)Cl

1 reference

Cryptophycin 1 (English)

14 October 2016

isomeric SMILES

C[C@@H]1CNC(=O)[C@H](NC(=O)/C=C/C[C@H](OC(=O)[C@@H](OC1=O)CC(C)C)[C@H](C)[C@@H]2[C@H](O2)C3=CC=CC=C3)CC4=CC(=C(C=C4)OC)Cl

1 reference

Structure determination, conformational analysis, chemical stability studies, and antitumor evaluation of the cryptophycins. Isolation of 18 new analogs from Nostoc sp. strain GSV 224

Cryptophycin 1 (English)

14 October 2016

5 references

Induction of apoptosis by cryptophycin 1, a new antimicrotubule agent

Structure determination, conformational analysis, chemical stability studies, and antitumor evaluation of the cryptophycins. Isolation of 18 new analogs from Nostoc sp. strain GSV 224

Isolation and Structure Determination of Cryptophycins 38, 326, and 327 from the Terrestrial CyanobacteriumNostocsp. GSV 224†

Three new cryptophycins from Nostoc sp. GSV 224

subject has role

tubulin modulators

1 reference

15 March 2018

1 reference

15 March 2018

1 reference

MeSH descriptor ID

C088419

InChI=1S/C35H43ClN2O8/c1-20(2)16-29-35(42)44-27(22(4)31-32(46-31)24-10-7-6-8-11-24)12-9-13-30(39)38-26(33(40)37-19-21(3)34(41)45-29)18-23-14-15-28(43-5)25(36)17-23/h6-11,13-15,17,20-22,26-27,29,31-32H,12,16,18-19H2,1-5H3,(H,37,40)(H,38,39)/b13-9+/t21-,22+,26-,27+,29+,31-,32-/m1/s1

15 March 2018

Identifiers

InChI

1 reference

Cryptophycin 1 (English)

14 October 2016

1 reference

Global Substance Registration System

Cryptophycin 1 (English)

14 October 2016

1 reference

UNII

XO974V2M5T

cryptophycin 1 (English)

14 October 2016

1 reference

cryptophycin-1 (English)

14 October 2016

2 references

Cryptophycin 1 (English)

matched by identifier from

14 October 2016

1 reference

matched by identifier from

CRYPTOPHYCIN A (English)

14 October 2016

1 reference

1 reference

MeSH descriptor ID

C088419

1 reference

Global Substance Registration System

14 March 2018

2 references

UNII

XO974V2M5T

cryptophycin 1 (English)

matched by identifier from

14 October 2016

inferred by common MeSH mappings on source and on Wikidata

UMLS CUI

C0257217

1 reference

based on heuristic

UMLS 2023