(Q27301311)

English

Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice

scientific article

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scholarly article

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Is L-methionine a trigger factor for Alzheimer's-like neurodegeneration?: Changes in Aβ oligomers, tau phosphorylation, synaptic proteins, Wnt signaling and behavioral impairment in wild-type mice (English)

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Alzheimer's disease

1 reference

based on heuristic

inferred from title

phosphorylation

1 reference

based on heuristic

inferred from title

neurodegeneration

1 reference

based on heuristic

inferred from title

author name string

Cheril Tapia-Rojas

1

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Carolina B Lindsay

2

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Carla Montecinos-Oliva

3

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Macarena S Arrazola

4

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Rocio M Retamales

5

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Daniel Bunout

6

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Sandra Hirsch

7

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Nibaldo C Inestrosa

8

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

language of work or name

0 references

publication date

21 November 2015

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Molecular Neurodegeneration

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

10

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

1

0 references

62

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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21 March 2017

Methionine residues as endogenous antioxidants in proteins

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21 March 2017

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

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21 March 2017

Endoplasmic reticulum stress-inducible protein, Herp, enhances presenilin-mediated generation of amyloid beta-protein

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21 March 2017

Loss of synaptic but not cytoskeletal proteins in the cerebellum of chronic schizophrenics

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21 March 2017

The sulfur-containing amino acids: an overview

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21 March 2017

Induction of Dickkopf-1, a negative modulator of the Wnt pathway, is associated with neuronal degeneration in Alzheimer's brain

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21 March 2017

Phosphorylation of tau at both Thr 231 and Ser 262 is required for maximal inhibition of its binding to microtubules

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21 March 2017

Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation

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21 March 2017

Role of the Wnt receptor Frizzled-1 in presynaptic differentiation and function

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21 March 2017

STI571 prevents apoptosis, tau phosphorylation and behavioural impairments induced by Alzheimer's beta-amyloid deposits

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21 March 2017

Inhibition of the canonical Wnt signaling pathway by apolipoprotein E4 in PC12 cells

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21 March 2017

A specific amyloid-beta protein assembly in the brain impairs memory

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21 March 2017

Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils

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21 March 2017

Decreased dendritic spine density on prefrontal cortical pyramidal neurons in schizophrenia

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7 April 2017

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

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10 May 2017

Deficiency in LRP6-mediated Wnt signaling contributes to synaptic abnormalities and amyloid pathology in Alzheimer's disease.

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28 September 2017

Wnt signalling in neuronal differentiation and development.

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28 September 2017

Wnt signaling in the nervous system and in Alzheimer's disease.

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28 September 2017

Lifetime requirement of the methionine cycle for neuronal development and maintenance

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28 September 2017

The impact of dietary methionine restriction on biomarkers of metabolic health

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28 September 2017

Plasma homocysteine, Alzheimer and cerebrovascular pathology: a population-based autopsy study

1 reference

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28 September 2017

WNT signaling in neuronal maturation and synaptogenesis

1 reference

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28 September 2017

Nutritional essentiality of sulfur in health and disease.

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28 September 2017

Aberrant protein s-nitrosylation in neurodegenerative diseases

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28 September 2017

Brain amyloid-β oligomers in ageing and Alzheimer's disease

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28 September 2017

Tetrahydrohyperforin decreases cholinergic markers associated with amyloid-β plaques, 4-hydroxynonenal formation, and caspase-3 activation in AβPP/PS1 mice.

1 reference

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28 September 2017

New genes and new insights from old genes: update on Alzheimer disease

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28 September 2017

A reliable way to detect endogenous murine β-amyloid

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28 September 2017

Hippocampal proNGF signaling pathways and β-amyloid levels in mild cognitive impairment and Alzheimer disease

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28 September 2017

Neurotoxicity of amyloid β-protein: synaptic and network dysfunction

1 reference

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28 September 2017

Three decades of Wnts: a personal perspective on how a scientific field developed

1 reference

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28 September 2017

Wnt transmembrane signaling and long-term spatial memory

1 reference

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28 September 2017

Genome-wide identification of new Wnt/beta-catenin target genes in the human genome using CART method

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28 September 2017

Red and processed meat consumption and risk of incident coronary heart disease, stroke, and diabetes mellitus: a systematic review and meta-analysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

L-methionine decreases dendritic spine density in mouse frontal cortex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

The role of Wnt signaling in neuroprotection

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Emerging roles of Wnts in the adult nervous system

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Diet-induced hyperhomocysteinemia increases amyloid-beta formation and deposition in a mouse model of Alzheimer's disease

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

The Role of Methionine Oxidation/Reduction in the Regulation of Immune Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Protein S-nitrosylation in health and disease: a current perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Calcium/calmodulin-dependent protein kinase type IV is a target gene of the Wnt/beta-catenin signaling pathway.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Chemical pathology of homocysteine. IV. Excitotoxicity, oxidative stress, endothelial dysfunction, and inflammation.

1 reference

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28 September 2017

Meat consumption and the risk of type 2 diabetes: a systematic review and meta-analysis of cohort studies.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Molecular mechanisms of homocysteine toxicity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

From trans-methylation to cytosine methylation: evolution of the methylation hypothesis of schizophrenia

1 reference

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28 September 2017

Ameliorative role of Atorvastatin and Pitavastatin in L-Methionine induced vascular dementia in rats

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28 September 2017

Wnt-7a modulates the synaptic vesicle cycle and synaptic transmission in hippocampal neurons.

1 reference

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28 September 2017

Dietary methionine effects on plasma homocysteine and HDL metabolism in mice

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28 September 2017

Hyperhomocysteinemia, inflammation and autoimmunity

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28 September 2017

Common genetic variation within the low-density lipoprotein receptor-related protein 6 and late-onset Alzheimer's disease

1 reference

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28 September 2017

Synaptotoxicity in Alzheimer's disease: the Wnt signaling pathway as a molecular target

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation.

1 reference

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28 September 2017

Toxicity of methionine in humans

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28 September 2017

The effects of sulfur amino acid intake on immune function in humans

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28 September 2017

Methionine oxidation and aging

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28 September 2017

Control of muscle protein kinetics by acid-base balance

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28 September 2017

Acetylcholinesterase-Abeta complexes are more toxic than Abeta fibrils in rat hippocampus: effect on rat beta-amyloid aggregation, laminin expression, reactive astrocytosis, and neuronal cell loss

1 reference

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28 September 2017

Homocysteine and oxidative stress

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

The atherogenic effect of excess methionine intake

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28 September 2017

Oxidation of Methionine Residues of Proteins: Biological Consequences

1 reference

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28 September 2017

S-adenosyl-L-methionine for treatment of depression, osteoarthritis, and liver disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

S-nitrosylation in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

The methionine-homocysteine cycle and its effects on cognitive diseases

1 reference

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28 September 2017

Role of S-adenosyl-L-methionine in the treatment of depression: a review of the evidence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 September 2017

Cyclic oxidation and reduction of protein methionine residues is an important antioxidant mechanism

1 reference

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28 September 2017

Episodic-like memory in animals: psychological criteria, neural mechanisms and the value of episodic-like tasks to investigate animal models of neurodegenerative disease

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28 September 2017

Methionine residues may protect proteins from critical oxidative damage.

1 reference

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28 September 2017

Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

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28 September 2017

Neurotoxicity associated with dual actions of homocysteine at the N-methyl-D-aspartate receptor

1 reference

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28 September 2017

A Conspectus of Research on Amino Acid Requirements of Man

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28 September 2017

Amino acid requirements in adult man.

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28 September 2017

Transmethylation Hypothesis of Schizophrenia: Methionine and Nicotinic Acid

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28 September 2017

Tetrahydrohyperforin prevents cognitive deficit, Aβ deposition, tau phosphorylation and synaptotoxicity in the APPswe/PSEN1ΔE9 model of Alzheimer's disease: a possible effect on APP processing.

1 reference

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31 May 2018

Hyperhomocysteinemia increases beta-amyloid by enhancing expression of gamma-secretase and phosphorylation of amyloid precursor protein in rat brain

1 reference

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31 May 2018

The role of Wnt signaling in neuronal dysfunction in Alzheimer's Disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

31 May 2018

Effect of S-adenosyl-L-methionine on impairment of working memory induced in rats by cerebral ischemia and scopolamine.

1 reference

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31 May 2018

Bioavailability and lack of toxicity of S-adenosyl-L-methionine (SAMe) in humans

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21 January 2018

Long-term methionine exposure induces memory impairment on inhibitory avoidance task and alters acetylcholinesterase activity and expression in zebrafish (Danio rerio).

1 reference

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21 January 2018

Hyperhomocysteinemia induced by methionine dietary nutritional overload modulates acetylcholinesterase activity in the rat brain.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Homocysteine induces tau phosphorylation by inactivating protein phosphatase 2A in rat hippocampus

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Homocysteine activates calcium-mediated cell signaling mechanisms targeting the cytoskeleton in rat hippocampus

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Induction of Alzheimer's-like changes in brain of mice expressing mutant APP fed excess methionine.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Prenatal hyperhomocysteinemia as a model of oxidative stress of the brain

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1DeltaE9 mouse model of Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Canonical Wnt signaling is necessary for object recognition memory consolidation

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

In vivo activation of Wnt signaling pathway enhances cognitive function of adult mice and reverses cognitive deficits in an Alzheimer's disease model.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

The effect of increased concentrations of homocysteine on the concentration of (E)-4-hydroxy-2-nonenal in the plasma and cerebrospinal fluid of patients with Alzheimer's disease.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Relation between plasma homocysteine and Alzheimer's disease

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Homocysteine induces oxidative stress by uncoupling of NO synthase activity through reduction of tetrahydrobiopterin.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Multiple aspects of homocysteine neurotoxicity: glutamate excitotoxicity, kinase hyperactivation and DNA damage

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-beta deposition in mice

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Hyperhomocysteinemic Alzheimer's mouse model of amyloidosis shows increased brain amyloid beta peptide levels

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Homocysteine potentiates beta-amyloid neurotoxicity: role of oxidative stress

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Wnt-3a overcomes beta-amyloid toxicity in rat hippocampal neurons.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

The secreted Wnt antagonist Dickkopf-1 is required for amyloid β-mediated synaptic loss.

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Activity-dependent synaptic Wnt release regulates hippocampal long term potentiation

1 reference

https://api.crossref.org/works/10.1186%2FS13024-015-0057-0

21 January 2018

Alzheimer's disease treated patients showed different patterns for oxidative stress and inflammation markers.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 November 2018

Peroxisome proliferators reduce spatial memory impairment, synaptic failure, and neurodegeneration in brains of a double transgenic mice model of Alzheimer's disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 November 2018

Homocysteine as a predictor of cognitive decline in Alzheimer's disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 November 2018

Elevation in S-Adenosylhomocysteine and DNA Hypomethylation: Potential Epigenetic Mechanism for Homocysteine-Related Pathology

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4654847

28 November 2018

Wnt signaling function in Alzheimer's disease

1 reference

https://pubmed.ncbi.nlm.nih.gov/26590557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Blood S-adenosyl-L-methionine levels in psychiatric disorders

1 reference

https://pubmed.ncbi.nlm.nih.gov/26590557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Abnormalities of one-carbon metabolism in psychiatric disorders: study of methionine adenosyltransferase kinetics and lipid composition of erythrocyte membranes

1 reference

https://pubmed.ncbi.nlm.nih.gov/26590557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Screening of toxicity biomarkers for methionine excess in rats

1 reference

https://pubmed.ncbi.nlm.nih.gov/26590557

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1186/S13024-015-0057-0

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

Dimensions Publication ID

0 references

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PMC publication ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

PubMed publication ID

1 reference

Europe PubMed Central

PubMed publication ID

26 June 2017

ResearchGate publication ID

0 references

Sitelinks

Wikipedia(0 entries)

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Wikinews(0 entries)

Wikiquote(0 entries)

Wikisource(0 entries)

Wikiversity(0 entries)

Wikivoyage(0 entries)

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