(Q28570115)

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

title

Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by beta-amyloid fibrils (English)

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

Wingless-type MMTV integration site family, member 3A

31 October 2019

main subject

1 reference

GOA release 2020-03-11

1 reference

Giancarlo V De Ferrari

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Juan A Godoy

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

author name string

Chacón MA

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Barría MI

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Garrido JL

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Olivares G

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Reyes AE

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Alvarez A

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Bronfman M

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

Inestrosa NC

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

language of work or name

English

0 references

publication date

1 February 2003

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

volume

8

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

issue

2

2 references

31 January 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

page(s)

195-208

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

The origins of Alzheimer disease: a is for amyloid.

31 October 2019

cites work

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beta-amyloid fibrils induce tau phosphorylation and loss of microtubule binding.

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Tau protein kinase I is essential for amyloid beta-protein-induced neurotoxicity

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Activation of tau protein kinase I/glycogen synthase kinase-3beta by amyloid beta peptide (25-35) enhances phosphorylation of tau in hippocampal neurons.

21 January 2018

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wingless signaling acts through zeste-white 3, the Drosophila homolog of glycogen synthase kinase-3, to regulate engrailed and establish cell fate

21 January 2018

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Wnt signaling to beta-catenin involves two interactive components. Glycogen synthase kinase-3beta inhibition and activation of protein kinase C.

21 January 2018

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The Wnt/Ca2+ pathway: a new vertebrate Wnt signaling pathway takes shape

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The axis-inducing activity, stability, and subcellular distribution of beta-catenin is regulated in Xenopus embryos by glycogen synthase kinase 3

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beta-catenin is a target for the ubiquitin-proteasome pathway

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Evidence supporting WNT2 as an autism susceptibility gene.

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Molecular genetics and animal models in autistic disorder

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Abnormalities of Wnt signalling in schizophrenia--evidence for neurodevelopmental abnormality

21 January 2018

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Increased expression of Wnt-1 in schizophrenic brains

21 January 2018

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Does dysregulation of the Notch and wingless/Wnt pathways underlie the pathogenesis of Alzheimer's disease?

21 January 2018

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Presenilin 1 interaction in the brain with a novel member of the Armadillo family

21 January 2018

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The presenilin 1 protein is a component of a high molecular weight intracellular complex that contains beta-catenin

21 January 2018

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Abrogation of the presenilin 1/beta-catenin interaction and preservation of the heterodimeric presenilin 1 complex following caspase activation

21 January 2018

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Destabilization of beta-catenin by mutations in presenilin-1 potentiates neuronal apoptosis

21 January 2018

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Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of beta-catenin, a component of the presenilin protein complex

21 January 2018

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Inhibitory effect of a presenilin 1 mutation on the Wnt signalling pathway by enhancement of beta-catenin phosphorylation

21 January 2018

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Presenilin 1 associates with glycogen synthase kinase-3beta and its substrate tau

21 January 2018

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A molecular mechanism for the effect of lithium on development

21 January 2018

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Lithium inhibits glycogen synthase kinase-3 activity and mimics wingless signalling in intact cells

21 January 2018

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Protein kinase C is differentially stimulated by Wnt and Frizzled homologs in a G-protein-dependent manner

21 January 2018

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Rat hippocampal neurons in dispersed cell culture

21 January 2018

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Toxic effects of acetylcholinesterase on neuronal and glial-like cells in vitro

21 January 2018

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Differential regulation of glycogen synthase kinase 3beta by insulin and Wnt signaling

21 January 2018

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Developments of a water-maze procedure for studying spatial learning in the rat

21 January 2018

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Inactivation of glycogen synthase kinase-3 beta by phosphorylation: new kinase connections in insulin and growth-factor signalling

21 January 2018

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Roles of Wnt proteins in neural development and maintenance

21 January 2018

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A novel mammalian wnt gene, WNT8B, shows brain-restricted expression in early development, with sharply delimited expression boundaries in the developing forebrain

21 January 2018

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Delayed behavioral effects following intrahippocampal injection of aggregated A beta (1-42).

21 January 2018

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Amyloid-beta injection in rat amygdala alters tau protein but not mRNA expression.

21 January 2018

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Protective effects of idebenone and alpha-tocopherol on beta-amyloid-(1-42)-induced learning and memory deficits in rats: implication of oxidative stress in beta-amyloid-induced neurotoxicity in vivo

21 January 2018

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A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease

21 January 2018

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A beta peptide vaccination prevents memory loss in an animal model of Alzheimer's disease

21 January 2018

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Alzheimer's disease-like phosphorylation of the microtubule-associated protein tau by glycogen synthase kinase-3 in transfected mammalian cells.

21 January 2018

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Sequential phosphorylation of Tau by glycogen synthase kinase-3beta and protein kinase A at Thr212 and Ser214 generates the Alzheimer-specific epitope of antibody AT100 and requires a paired-helical-filament-like conformation

21 January 2018

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Distribution of active glycogen synthase kinase 3beta (GSK-3beta) in brains staged for Alzheimer disease neurofibrillary changes

21 January 2018

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Lithium protects cultured neurons against beta-amyloid-induced neurodegeneration

21 January 2018

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beta-amyloid peptide-induced death of PC 12 cells and cerebellar granule cell neurons is inhibited by long-term lithium treatment

21 January 2018

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Neuroprotective effects of chronic lithium on focal cerebral ischemia in rats

21 January 2018

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Lithium inhibits Alzheimer's disease-like tau protein phosphorylation in neurons.

21 January 2018

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Lithium reduces tau phosphorylation by inhibition of glycogen synthase kinase-3.

21 January 2018

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Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations.

21 January 2018

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Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants.

21 January 2018

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Long term lithium treatment suppresses p53 and Bax expression but increases Bcl-2 expression. A prominent role in neuroprotection against excitotoxicity

21 January 2018

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Decreased nuclear beta-catenin, tau hyperphosphorylation and neurodegeneration in GSK-3beta conditional transgenic mice

21 January 2018

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Assessment of protein kinase C isozymes by two-site enzyme immunoassay in human brains and changes in Alzheimer's disease

21 January 2018

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Cytosol protein kinase C downregulation in fibroblasts from Alzheimer's disease patients.

21 January 2018

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Reduced protein kinase C immunoreactivity and altered protein phosphorylation in Alzheimer's disease fibroblasts.

21 January 2018

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Inhibition of beta-amyloid production by activation of protein kinase C.

21 January 2018

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Alzheimer's-specific effects of soluble beta-amyloid on protein kinase C-alpha and -gamma degradation in human fibroblasts

21 January 2018

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Protein kinase C iota protects neural cells against apoptosis induced by amyloid beta-peptide.

21 January 2018

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Effects of amyloid peptides on cell viability and expression of neuropeptides in cultured rat dorsal root ganglion neurons: a role for free radicals and protein kinase C.

21 January 2018

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Cloning and characterization of a secreted frizzled-related protein that is expressed by the retinal pigment epithelium

21 January 2018

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Chromosome localization of the human oncogene INT1 to 12q13 by in situ hybridization

21 January 2018

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A novel human Wnt gene, WNT10B, maps to 12q13 and is expressed in human breast carcinomas

21 January 2018

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Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12.

21 January 2018

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Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity.

21 January 2018

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Isolation and characterization of LRP6, a novel member of the low density lipoprotein receptor gene family

21 January 2018

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21 January 2018

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Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics

21 January 2018

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cGMP mobilizes intracellular Ca2+ in sea urchin eggs by stimulating cyclic ADP-ribose synthesis

21 January 2018

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Wnt signaling function in Alzheimer's disease

21 January 2018

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7 January 2021

GSK3 beta forms a tetrameric complex with endogenous PS1-CTF/NTF and beta-catenin. Effects of the D257/D385A and FAD-linked mutations

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7 January 2021

The pathogenic L392V mutation of presenilin 1 decreases the affinity to glycogen synthase kinase-3 beta

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7 January 2021

Stable complexes involving acetylcholinesterase and amyloid-beta peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer's fibrils.

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7 January 2021

Anti-proliferative effect of two novel palmitoyl-carnitine analogs, selective inhibitors of protein kinase C conventional isoenzymes

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7 January 2021

Glycogen synthase kinase-3 beta phosphorylates tau protein at multiple sites in intact cells

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7 January 2021

Enhancement of hippocampal neurogenesis by lithium

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7 January 2021

Decreased levels of protein kinase C in Alzheimer brain

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7 January 2021

Evidence for genetic linkage of Alzheimer's disease to chromosome 10q

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7 January 2021

Identifiers

DOI

10.1038/SJ.MP.4001208

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12610652%20AND%20SRC:MED&resulttype=core&format=json

31 October 2019

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017