(Q54032799)

23 May 2018

title

Protein kinase C iota protects neural cells against apoptosis induced by amyloid beta-peptide. (English)

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23 May 2018

5

Mattson MP

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23 May 2018

author name string

Xie J

1

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23 May 2018

Guo Q

2

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23 May 2018

Zhu H

3

1 reference

23 May 2018

Wooten MW

4

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23 May 2018

publication date

1 October 2000

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23 May 2018

published in

Molecular Brain Research

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23 May 2018

volume

82

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23 May 2018

issue

1-2

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23 May 2018

page(s)

107-113

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23 May 2018

Tumor necrosis factors alpha and beta protect neurons against amyloid beta-peptide toxicity: evidence for involvement of a kappa B-binding factor and attenuation of peroxide and Ca2+ accumulation.

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The product of par-4, a gene induced during apoptosis, interacts selectively with the atypical isoforms of protein kinase C

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Ras, protein kinase C zeta, and I kappa B kinases 1 and 2 are downstream effectors of CD44 during the activation of NF-kappa B by hyaluronic acid fragments in T-24 carcinoma cells

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beta-Amyloid polypeptide increases calcium-uptake in PC12 cells: a possible mechanism for its cellular toxicity in Alzheimer's disease.

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Secreted forms of beta-amyloid precursor protein protect hippocampal neurons against amyloid beta-peptide-induced oxidative injury.

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Estrogens attenuate and corticosterone exacerbates excitotoxicity, oxidative injury, and amyloid beta-peptide toxicity in hippocampal neurons

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Alzheimer's presenilin mutation sensitizes neural cells to apoptosis induced by trophic factor withdrawal and amyloid beta-peptide: involvement of calcium and oxyradicals.

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Secreted beta-amyloid precursor protein counteracts the proapoptotic action of mutant presenilin-1 by activation of NF-kappaB and stabilization of calcium homeostasis

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Increased vulnerability of hippocampal neurons from presenilin-1 mutant knock-in mice to amyloid beta-peptide toxicity: central roles of superoxide production and caspase activation.

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Amyloid beta-peptide impairs ion-motive ATPase activities: evidence for a role in loss of neuronal Ca2+ homeostasis and cell death.

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Differential involvement of protein kinase C isozymes in Alzheimer's disease

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Caspase dependent DNA fragmentation might be associated with excitotoxicity in Alzheimer disease

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Ca2+-dependent and Ca2+-independent protein kinase C changes in the brain of patients with Alzheimer's disease

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7 January 2021

beta-Amyloid peptides destabilize calcium homeostasis and render human cortical neurons vulnerable to excitotoxicity

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Cellular actions of beta-amyloid precursor protein and its soluble and fibrillogenic derivatives

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Activation of NF-kappaB protects hippocampal neurons against oxidative stress-induced apoptosis: evidence for induction of manganese superoxide dismutase and suppression of peroxynitrite production and protein tyrosine nitration.

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Apoptosis in neurodegenerative disorders

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Protein kinase C-zeta activity but not level is decreased in Alzheimer's disease microvessels.

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7 January 2021

Atypical protein kinase C iota protects human leukemia cells against drug-induced apoptosis

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7 January 2021

Caspases: killer proteases

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7 January 2021

Cell death during development of the nervous system

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7 January 2021

Interaction of protein kinase C zeta with ZIP, a novel protein kinase C-binding protein

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7 January 2021

The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling

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7 January 2021

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7 January 2021

Immunohistochemical evidence for apoptosis in Alzheimer's disease.

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7 January 2021

The protein kinase C family for neuronal signaling

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7 January 2021

GADD45 is induced in Alzheimer's disease, and protects against apoptosis in vitro

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7 January 2021

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7 January 2021

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7 January 2021

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7 January 2021

Overexpression of atypical PKC in PC12 cells enhances NGF-responsiveness and survival through an NF-kappaB dependent pathway

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7 January 2021

Mapping of atypical protein kinase C within the nerve growth factor signaling cascade: relationship to differentiation and survival of PC12 cells

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7 January 2021

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Identifiers

DOI

1 reference

23 May 2018

PubMed ID

11042363

1 reference

23 May 2018