(Q27311229)

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An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging

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An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging (English)

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bioluminescence

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1 reference

based on heuristic

inferred from title

acute myeloid leukemia

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based on heuristic

inferred from title

1

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Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

8

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Klaus H Metzeler

15

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Irmela Jeremias

17

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Wolfgang Hiddemann

12

object named as

Wolfgang Hiddemann

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Nadine Sandhöfer

3

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Nadine Sandhöfer

1 reference

Europe PubMed Central

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7 June 2020

author name string

Maja Rothenberg

2

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Michela Carlet

4

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Cornelia Finkenzeller

5

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Christina Krupka

6

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Europe PubMed Central

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7 June 2020

Michaela Grunert

7

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Europe PubMed Central

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7 June 2020

Selim Corbacioglu

9

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Maya C André

11

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Stephanie Schneider

13

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Marion Subklewe

14

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

Karsten Spiekermann

16

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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publication date

2015

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7 June 2020

10

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

3

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

e0120925

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

copyright license

Creative Commons Attribution 4.0 International

20 March 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

Concise review: Leukemia stem cells in personalized medicine

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

VarScan 2: somatic mutation and copy number alteration discovery in cancer by exome sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

Fast and accurate short read alignment with Burrows-Wheeler transform

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

Development of functional human blood and immune systems in NOD/SCID/IL2 receptor {gamma} chain(null) mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

Prognostic relevance of integrated genetic profiling in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

A cell initiating human acute myeloid leukaemia after transplantation into SCID mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

21 March 2017

Clonal evolution in relapsed acute myeloid leukaemia revealed by whole-genome sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

7 April 2017

Pindel: a pattern growth approach to detect break points of large deletions and medium sized insertions from paired-end short reads

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

7 April 2017

Functional heterogeneity of genetically defined subclones in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

MYB down-regulation enhances sensitivity of U937 myeloid leukemia cells to the histone deacetylase inhibitor LBH589 in vitro and in vivo.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Crenolanib is active against models of drug-resistant FLT3-ITD-positive acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Transcription factor RUNX1 promotes survival of acute myeloid leukemia cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

In vivo expansion of co-transplanted T cells impacts on tumor re-initiating activity of human acute myeloid leukemia in NSG mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

AML cells are differentially sensitive to chemotherapy treatment in a human xenograft model.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Bioluminescence imaging of leukemia cell lines in vitro and in mouse xenografts: effects of monoclonal and polyclonal cell populations on intensity and kinetics of photon emission

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

In vivo imaging enables high resolution preclinical trials on patients' leukemia cells growing in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Multiplexed mAbs: a new strategy in preclinical time-domain imaging of acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Minimal residual disease in acute myeloid leukemia: coming of age.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

A clinically relevant population of leukemic CD34(+)CD38(-) cells in acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Detection of low prevalence somatic mutations in solid tumors with ultra-deep targeted sequencing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Noninvasive bioluminescent imaging of primary patient acute lymphoblastic leukemia: a strategy for preclinical modeling.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

BCL6 enables Ph+ acute lymphoblastic leukaemia cells to survive BCR-ABL1 kinase inhibition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Human acute myelogenous leukemia stem cells are rare and heterogeneous when assayed in NOD/SCID/IL2Rγc-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

AML xenograft efficiency is significantly improved in NOD/SCID-IL2RG mice constitutively expressing human SCF, GM-CSF and IL-3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Induction of cell cycle entry eliminates human leukemia stem cells in a mouse model of AML.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Insertional transformation of hematopoietic cells by self-inactivating lentiviral and gammaretroviral vectors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

CD47 is an adverse prognostic factor and therapeutic antibody target on human acute myeloid leukemia stem cells.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

A robust xenotransplantation model for acute myeloid leukemia

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Stem cell concepts renew cancer research

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Chemosensitization of acute myeloid leukemia (AML) following mobilization by the CXCR4 antagonist AMD3100.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Comparative proteomic phenotyping of cell lines and primary cells to assess preservation of cell type-specific functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Visualizing fewer than 10 mouse T cells with an enhanced firefly luciferase in immunocompetent mouse models of cancer

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Human acute leukemia cells injected in NOD/LtSz-scid/IL-2Rgamma null mice generate a faster and more efficient disease compared to other NOD/scid-related strains.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Biology of normal and acute myeloid leukemia stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Acute myeloid leukemia stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Human lymphoid and myeloid cell development in NOD/LtSz-scid IL2R gamma null mice engrafted with mobilized human hemopoietic stem cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Rapid and quantitative assessment of cancer treatment response using in vivo bioluminescence imaging

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Noninvasive assessment of tumor cell proliferation in animal models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Visualizing the kinetics of tumor-cell clearance in living animals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Development of human tumor cell line panels for use in disease-oriented drug screening

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

28 September 2017

Lentiviral marking of patient-derived acute lymphoblastic leukaemic cells allows in vivo tracking of disease progression.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

31 May 2018

AML engraftment in the NOD/SCID assay reflects the outcome of AML: implications for our understanding of the heterogeneity of AML.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

31 May 2018

The severe combined immunodeficient (SCID) mouse as a model for human myeloid leukemias

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

31 May 2018

Propagation of human blastic myeloid leukemias in the SCID mouse

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4368518

31 May 2018

CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell-engaging antibody AMG 330.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Acute myeloid leukemia originates from a hierarchy of leukemic stem cell classes that differ in self-renewal capacity

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Chemotherapy-resistant human AML stem cells home to and engraft within the bone-marrow endosteal region.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Engraftment of low numbers of pediatric acute lymphoid and myeloid leukemias into NOD/SCID/IL2Rcγnull mice reflects individual leukemogenecity and highly correlates with clinical outcome

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Dynamic tracking of human hematopoietic stem cell engraftment using in vivo bioluminescence imaging

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Leukemia-initiating cells of patient-derived acute lymphoblastic leukemia xenografts are sensitive toward TRAIL.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Stem cell gene expression programs influence clinical outcome in human leukemia.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Acute myeloid leukemia (AML)-reactive cytotoxic T lymphocyte clones rapidly expanded from CD8(+) CD62L((high)+) T cells of healthy donors prevent AML engraftment in NOD/SCID IL2Rgamma(null) mice.

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Stable and reproducible engraftment of primary adult and pediatric acute myeloid leukemia in NSG mice

1 reference

https://api.crossref.org/works/10.1371%2FJOURNAL.PONE.0120925

21 January 2018

Anti-CD38 antibody-mediated clearance of human repopulating cells masks the heterogeneity of leukemia-initiating cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/25793878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Human AML cells in NOD/SCID mice: engraftment potential and gene expression

1 reference

https://pubmed.ncbi.nlm.nih.gov/25793878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of variables determining the engraftment potential of human acute myeloid leukemia in the immunodeficient NOD/SCID human chimera model

1 reference

https://pubmed.ncbi.nlm.nih.gov/25793878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexistence of LMPP-like and GMP-like Leukemia Stem Cells in Acute Myeloid Leukemia

1 reference

https://pubmed.ncbi.nlm.nih.gov/25793878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Bioluminescent evaluation of the therapeutic effects of total body irradiation in a murine hematological malignancy model

1 reference

https://pubmed.ncbi.nlm.nih.gov/25793878

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1371/JOURNAL.PONE.0120925

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

2015PLoSO..1020925V

0 references

release_jlkan3sxkzbv3klkdpgvocafn4

0 references

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25793878%20AND%20SRC:MED&resulttype=core&format=json

7 June 2020

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