(Q39129437)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Carlo Vascotto

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Lisa Lirussi

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Daniela Damiani

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

Gianluca Tell

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

author name string

M Poletto

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

D Fabbro

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

G Damante

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

B Demple

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

E Colombo

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

language of work or name

English

0 references

publication date

8 July 2013

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

volume

33

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23831574%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

page(s)

2876-2887

1 reference

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https://scigraph.springernature.com/pub.10.1038/onc.2013.251

4 March 2020

exact match

0 references

cites work

Nucleophosmin and its complex network: a possible therapeutic target in hematological diseases.

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Nucleophosmin regulates the stability and transcriptional activity of p53

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Clinical relevance of mutations and gene-expression changes in adult acute myeloid leukemia with normal cytogenetics: are we ready for a prognostically prioritized molecular classification?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Myeloid leukemia-associated nucleophosmin mutants perturb p53-dependent and independent activities of the Arf tumor suppressor protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Delocalization and destabilization of the Arf tumor suppressor by the leukemia-associated NPM mutant

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Nucleophosmin and its AML-associated mutant regulate c-Myc turnover through Fbw7 gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Increase sensitivity to chemotherapeutical agents and cytoplasmatic interaction between NPM leukemic mutant and NF-kappaB in AML carrying NPM1 mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Nucleophosmin interacts with HEXIM1 and regulates RNA polymerase II transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

A ribosomal protein L23-nucleophosmin circuit coordinates Mizl function with cell growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Acute myeloid leukemia carrying cytoplasmic/mutated nucleophosmin (NPMc+ AML): biologic and clinical features

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Acute myeloid leukemia with mutated nucleophosmin (NPM1): is it a distinct entity?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Small molecule inhibitors of DNA repair nuclease activities of APE1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Thioredoxin-dependent redox regulation of p53-mediated p21 activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Roles of thioredoxin reductase 1 and APE/Ref-1 in the control of basal p53 stability and activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

HIF-1alpha, STAT3, CBP/p300 and Ref-1/APE are components of a transcriptional complex that regulates Src-dependent hypoxia-induced expression of VEGF in pancreatic and prostate carcinomas.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Role of the unstructured N-terminal domain of the hAPE1 (human apurinic/apyrimidinic endonuclease 1) in the modulation of its interaction with nucleic acids and NPM1 (nucleophosmin).

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Nucleophosmin is required for DNA integrity and p19Arf protein stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Nucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Role of APE1 in differentiated neuroblastoma SH-SY5Y cells in response to oxidative stress: use of APE1 small molecule inhibitors to delineate APE1 functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

DNA damage by bromate: mechanism and consequences

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Bleomycins: towards better therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Distinct roles of Ape1 protein in the repair of DNA damage induced by ionizing radiation or bleomycin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Synthesis, biological evaluation, and structure-activity relationships of a novel class of apurinic/apyrimidinic endonuclease 1 inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Proximity ligation assays: a recent addition to the proteomics toolbox

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Cytoplasmic nucleophosmin in acute myelogenous leukemia with a normal karyotype

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Cell line OCI/AML3 bears exon-12 NPM gene mutation-A and cytoplasmic expression of nucleophosmin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Human apurinic/apyrimidinic endonuclease (Ape1) and its N-terminal truncated form (AN34) are involved in DNA fragmentation during apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Functional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Redox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Two essential but distinct functions of the mammalian abasic endonuclease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Long patch base excision repair in mammalian mitochondrial genomes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Age- and tissue-specific changes in mitochondrial and nuclear DNA base excision repair activity in mice: Susceptibility of skeletal muscles to oxidative injury

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Mitochondrial localization of APE/Ref-1 in thyroid cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Bioinformatic processing to identify single nucleotide polymorphism that potentially affect Ape1 function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Ref-1/Ape is critical for formation of the hypoxia-inducible transcriptional complex on the hypoxic response element of the rat pulmonary artery endothelial cell VEGF gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

BRCA2 and nucleophosmin coregulate centrosome amplification and form a complex with the Rho effector kinase ROCK2

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251

Redox factor-1/APE suppresses oxidative stress by inhibiting the rac1 GTPase

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FONC.2013.251