(Q30497640)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

0 references

13

1 reference

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9 February 2020

Carlo Vascotto

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Chiara D'Ambrosio

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Andrea Scaloni

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

J. Pablo Radicella

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

5

Milena Romanello

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

author name string

Damiano Fantini

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Luigi Vitagliano

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Carlo Pedone

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Mattia Poletto

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Laura Cesaratto

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Franco Quadrifoglio

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

Daniela Marasco

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

language of work or name

English

0 references

publication date

10 August 2010

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

published in

Nucleic Acids Research

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

volume

38

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

issue

22

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

page(s)

8239-8256

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution-NonCommercial 2.5 Generic

9 February 2020

copyright license

start time

4 October 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

cites work

SIRT1 deacetylates APE1 and regulates cellular base excision repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Intrusion of a DNA repair protein in the RNome world: is this the beginning of a new era?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Ubiquitination of mammalian AP endonuclease (APE1) regulated by the p53-MDM2 signaling pathway

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Genome-wide analysis and proteomic studies reveal APE1/Ref-1 multifunctional role in mammalian cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Structural insights into the interaction between the Cripto CFC domain and the ALK4 receptor.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

The many functions of APE1/Ref-1: not only a DNA repair enzyme

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Characterization of abasic endonuclease activity of human Ape1 on alternative substrates, as well as effects of ATP and sequence context on AP site incision

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Recent developments in the MAFFT multiple sequence alignment program

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

APE1/Ref-1 regulates PTEN expression mediated by Egr-1

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Cockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediates

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

MEGA4: Molecular Evolutionary Genetics Analysis (MEGA) Software Version 4.0

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Human base excision repair complex is physically associated to DNA replication and cell cycle regulatory proteins

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Cooperative activity of Ref-1/APE and ERp57 in reductive activation of transcription factors.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Nucleotide sequence and DNA secondary structure, as well as replication protein A, modulate the single-stranded abasic endonuclease activity of APE1.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

DNA damage disrupts the p14ARF-B23(nucleophosmin) interaction and triggers a transient subnuclear redistribution of p14ARF.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Hyperphosphorylation of JNK-interacting protein 1, a protein associated with Alzheimer disease.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Analysis of nuclear transport signals in the human apurinic/apyrimidinic endonuclease (APE1/Ref1).

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Two essential but distinct functions of the mammalian abasic endonuclease

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

The intracellular localization of APE1/Ref-1: more than a passive phenomenon?

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

A vital role for Ape1/Ref1 protein in repairing spontaneous DNA damage in human cells.

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Human AP endonuclease (APE1) demonstrates endonucleolytic activity against AP sites in single-stranded DNA

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Role of acetylated human AP-endonuclease (APE1/Ref-1) in regulation of the parathyroid hormone gene

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Disruption of the nucleolus mediates stabilization of p53 in response to DNA damage and other stresses

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Redox factor-1 contributes to the regulation of progression from G0/G1 to S by PDGF in vascular smooth muscle cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Cleaving the oxidative repair protein Ape1 enhances cell death mediated by granzyme A

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Nucleophosmin regulates the stability and transcriptional activity of p53

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Human AP-endonuclease 1 and hnRNP-L interact with a nCaRE-like repressor element in the AP-endonuclease 1 promoter

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

XRCC1 coordinates the initial and late stages of DNA abasic site repair through protein-protein interactions

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Mitochondrial localization of APE/Ref-1 in thyroid cells

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Intrinsically unstructured proteins: re-assessing the protein structure-function paradigm

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Dynamics of the interaction of human apurinic endonuclease (Ape1) with its substrate and product

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

The interaction between Ku antigen and REF1 protein mediates negative gene regulation by extracellular calcium

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

The redox and DNA-repair activities of Ref-1 are encoded by nonoverlapping domains

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

The neighbor-joining method: a new method for reconstructing phylogenetic trees

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Basic local alignment search tool

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Solid phase peptide synthesis utilizing 9-fluorenylmethoxycarbonyl amino acids

20 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3001066

Domain mapping of human apurinic/apyrimidinic endonuclease. Structural and functional evidence for a disordered amino terminus and a tight globular carboxyl domain.

20 June 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Drosophila Rrp1 domain structure as defined by limited proteolysis and biophysical analyses.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Drosophila DNA polymerase zeta interacts with recombination repair protein 1, the Drosophila homologue of human abasic endonuclease 1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Granzyme K degrades the redox/DNA repair enzyme Ape1 to trigger oxidative stress of target cells leading to cytotoxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Intracellular trafficking and regulation of mammalian AP-endonuclease 1 (APE1), an essential DNA repair protein.

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Ape1 abasic endonuclease activity is regulated by magnesium and potassium concentrations and is robust on alternative DNA structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Probing conformational changes in Ape1 during the progression of base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1093%2FNAR%2FGKQ691

Immobilization of proteins to a carboxymethyldextran-modified gold surface for biospecific interaction analysis in surface plasmon resonance sensors

21 January 2018

1 reference

12 December 2020

Preparation of the very acid‐sensitive Fmoc‐Lys(Mtt)‐OH Application in the synthesis of side‐chain to side‐chain cyclic peptides and oligolysine cores suitable for the solid‐phase assembly of MAPs and TASPs

1 reference

12 December 2020

Deletion analysis of human AP-endonuclease: minimum sequence required for the endonuclease activity

1 reference

12 December 2020

Effect of aging on intracellular distribution of abasic (AP) endonuclease 1 in the mouse liver

1 reference

12 December 2020

Identifiers

DOI

10.1093/NAR/GKQ691

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20699270%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

1 reference