(Q34367294)

1 August 2017

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title

BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis (English)

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1 August 2017

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Kaina B

1

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1 August 2017

Ochs K

2

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1 August 2017

Grösch S

3

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1 August 2017

Fritz G

4

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1 August 2017

Lips J

5

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1 August 2017

Tomicic M

6

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1 August 2017

Dunkern T

7

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1 August 2017

Christmann M

8

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1 August 2017

publication date

1 January 2001

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Progress in Molecular Biology and Translational Science

1 August 2017

published in

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1 August 2017

volume

68

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1 August 2017

page(s)

41-54

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Exposure of humans to endogenous N-nitroso compounds: implications in cancer etiology

1 August 2017

cites work

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Apoptosis by death factor

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Contribution of O6-alkylguanine and N-alkylpurines to the formation of sister chromatid exchanges, chromosomal aberrations, and gene mutations: new insights gained from studies of genetically engineered mammalian cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

DNA repair and chromosomal stability in the alkylating agent-hypersensitive Chinese hamster cell line 27-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Transgenic systems in studies on genotoxicity of alkylating agents: critical lesions, thresholds and defense mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

On the quantitative relationship between O6-methylguanine residues in genomic DNA and production of sister-chromatid exchanges, mutations and lethal events in a Mer- human tumor cell line

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

DNA damage tolerance, mismatch repair and genome instability

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

O6-alkylguanine DNA lesions trigger apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Alkylation-induced apoptosis of embryonic stem cells in which the gene for DNA-repair, methyltransferase, had been disrupted by gene targeting.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

A role for mismatch repair in production of chromosome aberrations by methylating agents in human cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Overexpression of human DNA repair protein N-methylpurine-DNA glycosylase results in the increased removal of N-methylpurines in DNA without a concomitant increase in resistance to alkylating agents in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Heterogeneous repair of N-methylpurines at the nucleotide level in normal human cells

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Alkylpurine-DNA-N-glycosylase knockout mice show increased susceptibility to induction of mutations by methyl methanesulfonate

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Expression of yeast but not human apurinic/apyrimidinic endonuclease renders Chinese hamster cells more resistant to DNA damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

A role for the human DNA repair enzyme HAP1 in cellular protection against DNA damaging agents and hypoxic stress

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Mammalian base excision repair and DNA polymerase beta

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Requirement of mammalian DNA polymerase-beta in base-excision repair.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Induction of the alkyltransferase (MGMT) gene by DNA damaging agents and the glucocorticoid dexamethasone and comparison with the response of base excision repair genes.

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

p53 is involved in regulation of the DNA repair gene O6-methylguanine-DNA methyltransferase (MGMT) by DNA damaging agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Isolation and analysis of inducibility of the rat N-methylpurine-DNA glycosylase promoter

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Induction of beta-polymerase mRNA by DNA-damaging agents in Chinese hamster ovary cells

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Identification of redox/repair protein Ref-1 as a potent activator of p53

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Negative regulation of the major human AP-endonuclease, a multifunctional protein

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Deletion analysis of human AP-endonuclease: minimum sequence required for the endonuclease activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Site-directed mutagenesis of the human DNA repair enzyme HAP1: identification of residues important for AP endonuclease and RNase H activity

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Identification of residues in the human DNA repair enzyme HAP1 (Ref-1) that are essential for redox regulation of Jun DNA binding

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Phosphorylation of the DNA repair protein APE/REF-1 by CKII affects redox regulation of AP-1

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Transcriptional activation of apurinic/apyrimidinic endonuclease (Ape, Ref-1) by oxidative stress requires CREB

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Second pathway for completion of human DNA base excision-repair: reconstitution with purified proteins and requirement for DNase IV (FEN1).

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Critical steps in alkylation-induced aberration formation

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https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

Repair of DNA containing O6-alkylguanine

1 reference

https://api.crossref.org/works/10.1016%2FS0079-6603%2801%2968088-7

7 January 2021

10.1016/S0079-6603(01)68088-7

Identifiers

DOI

1 reference

1 August 2017

1 reference