(Q27329427)

26 June 2017

Clonal dynamics following p53 loss of heterozygosity in Kras-driven cancers (English)

1 reference

26 June 2017

1 reference

Mandar Deepak Muzumdar

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Tuomas Tammela

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Carman Man-Chung Li

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

8

Tyler Jacks

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

author name string

Kimberly Judith Dorans

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Katherine Minjee Chung

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Rebecca Robbins

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

Vasilena Gocheva

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

language of work or name

English

0 references

publication date

2 September 2016

1 reference

26 June 2017

Nature Communications

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

volume

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

page(s)

12685

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

13 June 2020

copyright license

start time

2 September 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

0 references

describes a project that uses

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC5025814/fullTextXML

inferred from PubMed Central ID database lookup

cites work

Cancer genome landscapes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Genome remodelling in a basal-like breast cancer metastasis and xenograft

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Toward understanding and exploiting tumor heterogeneity

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma

21 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Structural and molecular interrogation of intact biological systems

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

EMT and dissemination precede pancreatic tumor formation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Tumor spectrum analysis in p53-mutant mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Reactivation of multipotency by oncogenic PIK3CA induces breast tumour heterogeneity.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

STAT3 regulated ARF expression suppresses prostate cancer metastasis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Intratumoral Heterogeneity: From Diversity Comes Resistance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

A next-generation dual-recombinase system for time- and host-specific targeting of pancreatic cancer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Supporting conditional mouse mutagenesis with a comprehensive cre characterization resource

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Lineage tracing reveals Lgr5+ stem cell activity in mouse intestinal adenomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Mosaic analysis with double markers reveals tumor cell of origin in glioma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Stage-specific sensitivity to p53 restoration during lung cancer progression.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Selective activation of p53-mediated tumour suppression in high-grade tumours

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Tissue-specific p19Arf regulation dictates the response to oncogenic K-ras

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Stage-specific Arf tumor suppression in Notch1-induced T-cell acute lymphoblastic leukemia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Conditional mouse lung cancer models using adenoviral or lentiviral delivery of Cre recombinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

The inherent instability of mutant p53 is alleviated by Mdm2 or p16INK4a loss

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Modeling sporadic loss of heterozygosity in mice by using mosaic analysis with double markers (MADM)

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Genetics and biology of pancreatic ductal adenocarcinoma.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Mosaic analysis with double markers in mice.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Progression model for pancreatic cancer.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Induction of ARF tumor suppressor gene expression and cell cycle arrest by transcription factor DMP1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Defining the mode of tumour growth by clonal analysis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5025814

Selective requirement of PI3K/PDK1 signaling for Kras oncogene-driven pancreatic cell plasticity and cancer

2 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS12685

AP-1 dimers regulate transcription of the p14/p19ARF tumor suppressor gene.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCOMMS12685

The differential effects of mutant p53 alleles on advanced murine lung cancer

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27585860

12 December 2020

inferred from PubMed ID database lookup

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27585860

12 December 2020

inferred from PubMed ID database lookup

p53 alterations in atypical alveolar hyperplasia of the human lung

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27585860

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NCOMMS12685

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

13 June 2020

ADS bibcode

2016NatCo...712685M

0 references

1003540054

0 references

Fatcat ID

release_aieo5d4uw5epxg56ur7lkg7gzy

0 references

OpenCitations bibliographic resource ID

3704978

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2 references

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

3704978

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27585860%20AND%20SRC:MED&resulttype=core&format=json

13 June 2020

1 reference