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Activation of the E3 ubiquitin ligase Parkin.
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scholarly article
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
review article
1 reference
stated in
Europe PubMed Central
title
Activation of the E3 ubiquitin ligase Parkin
(English)
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
author
Fabienne C. Fiesel
series ordinal
2
1 reference
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Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
Wolfdieter Springer
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3
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
T.R. Caulfield
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1
object named as
Thomas R Caulfield
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
publication date
1 April 2015
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
published in
Biochemical Society Transactions
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
volume
43
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
issue
2
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
page(s)
269-274
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
cites work
Phosphorylation by PINK1 releases the UBL domain and initializes the conformational opening of the E3 ubiquitin ligase Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
Ubiquitin is phosphorylated by PINK1 to activate parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy
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PubMed Central
reference URL
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21 March 2017
A molecular explanation for the recessive nature of parkin-linked Parkinson’s disease
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PubMed Central
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21 March 2017
Structure and function of Parkin E3 ubiquitin ligase reveals aspects of RING and HECT ligases
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PubMed Central
reference URL
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21 March 2017
Structure of the human Parkin ligase domain in an autoinhibited state
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PubMed Central
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21 March 2017
Structure of parkin reveals mechanisms for ubiquitin ligase activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
Structural basis for autoinhibition and phosphorylation-dependent activation of c-Cbl
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PubMed Central
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21 March 2017
UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
PINK1 is selectively stabilized on impaired mitochondria to activate Parkin
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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21 March 2017
PINK1 phosphorylates ubiquitin to activate Parkin E3 ubiquitin ligase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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7 April 2017
Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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7 April 2017
Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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7 April 2017
PINK1 stabilized by mitochondrial depolarization recruits Parkin to damaged mitochondria and activates latent Parkin for mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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7 April 2017
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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7 April 2017
PINK1 is activated by mitochondrial membrane potential depolarization and stimulates Parkin E3 ligase activity by phosphorylating Serine 65
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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7 April 2017
Quantitative proteomics reveal a feedforward mechanism for mitochondrial PARKIN translocation and ubiquitin chain synthesis.
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
PINK1 triggers autocatalytic activation of Parkin to specify cell fate decisions
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
A specific subset of E2 ubiquitin-conjugating enzymes regulate Parkin activation and mitophagy differently
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
Phosphorylation of Parkin at Serine65 is essential for activation: elaboration of a Miro1 substrate-based assay of Parkin E3 ligase activity
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
Macromolecular juggling by ubiquitylation enzymes
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
Mutations in the intellectual disability gene Ube2a cause neuronal dysfunction and impair parkin-dependent mitophagy
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
The dual functions of the extreme N-terminus of TDP-43 in regulating its biological activity and inclusion formation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
PINK1-mediated phosphorylation of the Parkin ubiquitin-like domain primes mitochondrial translocation of Parkin and regulates mitophagy
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
What genetics tells us about the causes and mechanisms of Parkinson's disease
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
Examinations of tRNA Range of Motion Using Simulations of Cryo-EM Microscopy and X-Ray Data
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
Regulation of PINK1-Parkin-mediated mitophagy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
retrieved
28 September 2017
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
retrieved
28 September 2017
Activation of the E3 ubiquitin ligase Itch through a phosphorylation-induced conformational change
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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28 September 2017
Lysine 63-linked polyubiquitination is dispensable for Parkin-mediated mitophagy
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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2 June 2018
Phosphorylated ubiquitin: a new shade of PINK1 in Parkin activation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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2 June 2018
Parkin-catalyzed ubiquitin-ester transfer is triggered by PINK1-dependent phosphorylation.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
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2 June 2018
Parkin mitochondrial translocation is achieved through a novel catalytic activity coupled mechanism
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
retrieved
2 June 2018
The ubiquitin-conjugating enzymes UBE2N, UBE2L3 and UBE2D2/3 are essential for Parkin-dependent mitophagy.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
retrieved
27 November 2018
Motion of transfer RNA from the A/T state into the A-site using docking and simulations.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4859148
retrieved
27 November 2018
Cbl exposes its RING finger
1 reference
stated in
PubMed
reference URL
https://pubmed.ncbi.nlm.nih.gov/25849928
retrieved
12 December 2020
based on heuristic
inferred from PubMed ID database lookup
Identifiers
DOI
10.1042/BST20140321
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
PMC publication ID
4859148
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
PubMed publication ID
25849928
1 reference
stated in
Europe PubMed Central
PMC publication ID
4859148
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849928%20AND%20SRC:MED&resulttype=core&format=json
retrieved
4 March 2020
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