(Q27335319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

title

Interleukin-1β protects astrocytes against oxidant-induced injury via an NF-κB-dependent upregulation of glutathione synthesis (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

0 references

0 references

0 references

1 reference

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

author name string

Yan He

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Nicole A Jackman

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Trista L Thorn

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

Valarie E Vought

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

language of work or name

English

0 references

publication date

16 April 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

volume

63

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

issue

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

page(s)

1568-1580

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

describes a project that uses

5 March 2020

ImageJ

1 reference

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC4506211/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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21 March 2017

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21 March 2017

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Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

21 March 2017

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A low dose of recombinant interleukin 1 protects granulocytopenic mice from lethal gram-negative infection

21 March 2017

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21 March 2017

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Dual TNFα-induced effects on NRF2 mediated antioxidant defence in astrocyte-rich cultures: role of protein kinase activation

21 March 2017

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21 March 2017

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Glutathione release from cultured brain cells: multidrug resistance protein 1 mediates the release of GSH from rat astroglial cells

21 March 2017

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Ciliary neurotrophic factor activates spinal cord astrocytes, stimulating their production and release of fibroblast growth factor-2, to increase motor neuron survival

21 March 2017

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Identification and characterisation of human xCT that co-expresses, with 4F2 heavy chain, the amino acid transport activity system xc-

21 March 2017

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Immunological and inflammatory functions of the interleukin-1 family

21 March 2017

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Astrocytes are active players in cerebral innate immunity

7 April 2017

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Redox environment of the cell as viewed through the redox state of the glutathione disulfide/glutathione couple

7 April 2017

1 reference

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Interleukin-1β in Central Nervous System Injury and Repair.

7 April 2017

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Interleukin-1 beta enhances endocytosis of glial glutamate transporters in the spinal dorsal horn through activating protein kinase C.

29 September 2017

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Astrocyte functions in the copper homeostasis of the brain.

29 September 2017

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Hypoxia-inducible factor 1 protects hypoxic astrocytes against glutamate toxicity

29 September 2017

1 reference

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Interleukin-1 and stroke: biomarker, harbinger of damage, and therapeutic target

29 September 2017

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The Nrf2-inducible antioxidant defense in astrocytes can be both up- and down-regulated by activated microglia:Involvement of p38 MAPK.

29 September 2017

1 reference

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Regulation of system x(c)(-)activity and expression in astrocytes by interleukin-1β: implications for hypoxic neuronal injury

29 September 2017

1 reference

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Sustained expression of interleukin-1beta in mouse hippocampus impairs spatial memory

29 September 2017

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Determinants of regional and local diversity within the astroglial lineage of the normal central nervous system

29 September 2017

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Inflammatory cytokines IL-1β and TNF-α regulate p75NTR expression in CNS neurons and astrocytes by distinct cell-type-specific signalling mechanisms

29 September 2017

1 reference

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Sustained hippocampal IL-1 beta overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology

29 September 2017

1 reference

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Interleukin-1beta mediates GDNF up-regulation upon dopaminergic injury in ventral midbrain cell cultures

29 September 2017

1 reference

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Inhibition of astroglial nuclear factor kappaB reduces inflammation and improves functional recovery after spinal cord injury

29 September 2017

1 reference

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IL-1-regulated responses in astrocytes: relevance to injury and recovery

29 September 2017

1 reference

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Interleukin-1beta upregulates functional expression of neurokinin-1 receptor (NK-1R) via NF-kappaB in astrocytes

29 September 2017

1 reference

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Pro-regenerative properties of cytokine-activated astrocytes.

29 September 2017

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Glutathione metabolism and its implications for health

29 September 2017

1 reference

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Coordinate Regulation of Glutathione Biosynthesis and Release by Nrf2-Expressing Glia Potently Protects Neurons from Oxidative Stress

29 September 2017

1 reference

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Innate immunity: the missing link in neuroprotection and neurodegeneration?

29 September 2017

1 reference

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Structure, function, and regulation of human cystine/glutamate transporter in retinal pigment epithelial cells

29 September 2017

1 reference

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U373-MG response to interleukin-1beta-induced oxidative stress.

29 September 2017

1 reference

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Glutathione metabolism in brain metabolic interaction between astrocytes and neurons in the defense against reactive oxygen species

29 September 2017

1 reference

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Glutathione, oxidative stress and neurodegeneration

29 September 2017

1 reference

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Metabolism and functions of glutathione in brain.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

NF-kappa B: a crucial transcription factor for glial and neuronal cell function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Long exposure to high glucose concentration impairs the responsive expression of gamma-glutamylcysteine synthetase by interleukin-1beta and tumor necrosis factor-alpha in mouse endothelial cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Role of membrane transport in metabolism and function of glutathione in mammals

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Interleukin 1 pretreatment decreases ischemia/reperfusion injury

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Cholinergic sprouting in the hippocampus: a proposed role for IL-1.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Cyclooxygenase-1 mediates prostaglandin E(2) elevation and contextual memory impairment in a model of sustained hippocampal interleukin-1beta expression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Interleukin-1beta exacerbates hypoxia-induced neuronal damage, but attenuates toxicity produced by simulated ischaemia and excitotoxicity in rat organotypic hippocampal slice cultures

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Induction of COX-2 and PGE(2) biosynthesis by IL-1beta is mediated by PKC and mitogen-activated protein kinases in murine astrocytes

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Interleukin-1 promotes expression and phosphorylation of neurofilament and tau proteins in vivo

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Synthesis of the antioxidant glutathione in neurons: supply by astrocytes of CysGly as precursor for neuronal glutathione

2 June 2018

1 reference

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Involvement of cytokines in normal CNS development and neurological diseases: recent progress and perspectives

2 June 2018

1 reference

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Astrocyte-mediated enhancement of neuronal survival is abolished by glutathione deficiency

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

In vivo and in vitro evidence supporting a role for the inflammatory cytokine interleukin-1 as a driving force in Alzheimer pathogenesis

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Intrastriatal implantation of interleukin-1. Reduction of parkinsonism in rats by enhancing neuronal sprouting from residual dopaminergic neurons in the ventral tegmental area of the midbrain

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Blood-brain barrier restriction of peptides and the low uptake of enkephalins

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat.

2 June 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Progressive neurodegeneration and motor disabilities induced by chronic expression of IL-1beta in the substantia nigra.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Interleukin-1beta potentiates neuronal injury in a variety of injury models involving energy deprivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Regulation of nerve growth factor mRNA by interleukin-1 in rat hippocampal astrocytes is mediated by NFkappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Co-culture of neurones with glutathione deficient astrocytes leads to increased neuronal susceptibility to nitric oxide and increased glutamate-cysteine ligase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Characterization of an improved procedure for the removal of microglia from confluent monolayers of primary astrocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Interleukin-1 beta is required for the early evolution of reactive astrogliosis following CNS lesion.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Quantitative imaging of glutathione in hippocampal neurons and glia in culture using monochlorobimane

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Extracellular and intracellular glutathione protects astrocytes from Zn2+-induced cell death

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Increased expression of glutathione by estradiol, tumor necrosis factor-alpha, and interleukin 1-beta in endometrial stromal cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Endogenous glutathione and catalase protect cultured rat astrocytes from the iron-mediated toxicity of hydrogen peroxide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Comparison of the LDH and MTT assays for quantifying cell death: validity for neuronal apoptosis?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

The effects of glutathione and vitamin E on iron toxicity in isolated rat hepatocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

The multidrug resistance protein 1 (Mrp1), but not Mrp5, mediates export of glutathione and glutathione disulfide from brain astrocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Attenuation of murine collagen-induced arthritis by a novel, potent, selective small molecule inhibitor of IkappaB Kinase 2, TPCA-1 (2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide), occurs via reduction of proinflammatory cytokin

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Cytokine-mediated induction of ceramide production is redox-sensitive. Implications to proinflammatory cytokine-mediated apoptosis in demyelinating diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Two-photon imaging of glutathione levels in intact brain indicates enhanced redox buffering in developing neurons and cells at the cerebrospinal fluid and blood-brain interface

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

IL-1beta enhances the antibacterial activity of astrocytes by activation of NF-kappaB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FGLIA.22828

Changes in intracellular calcium and glutathione in astrocytes as the primary mechanism of amyloid neurotoxicity.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

The relationship between intracellular free iron and cell injury in cultured neurons, astrocytes, and oligodendrocytes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Inflammatory cytokines IL-1 alpha, IL-1 beta, IL-6, and TNF-alpha impart neuroprotection to an excitotoxin through distinct pathways

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4506211

Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis

27 November 2018

1 reference

12 December 2020

Activation of astrocyte intracellular signaling pathways by interleukin-1 in rat primary striatal cultures

1 reference

12 December 2020

Generation of primary astrocyte cultures devoid of contaminating microglia

1 reference

12 December 2020

Glutathione efflux from cultured astrocytes

1 reference

12 December 2020

Glutathione is present in high concentrations in cultured astrocytes but not in cultured neurons

1 reference

12 December 2020

The gamma-glutamyl transpeptidase inhibitor acivicin preserves glutathione released by astroglial cells in culture

1 reference

12 December 2020

System x(c)- activity and astrocytes are necessary for interleukin-1 beta-mediated hypoxic neuronal injury

1 reference

12 December 2020

Rapid clearance of tertiary butyl hydroperoxide by cultured astroglial cells via oxidation of glutathione

1 reference

12 December 2020

IL-1beta promotes neurite outgrowth by deactivating RhoA via p38 MAPK pathway

1 reference

12 December 2020

Glutathione turnover in cultured astrocytes: studies with [15N]glutamate

1 reference

12 December 2020

Maintenance of neuronal glutathione by glial cells

1 reference

12 December 2020

Enhanced hematopoietic recovery in irradiated mice pretreated with interleukin-1 (IL-1)

1 reference

12 December 2020

Astrocytes provide cysteine to neurons by releasing glutathione

1 reference

12 December 2020

Identifiers

DOI

10.1002/GLIA.22828

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json

5 March 2020

PubMed publication ID

25880604

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25880604%20AND%20SRC:MED&resulttype=core&format=json