(Q81324672)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881516%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

title

System x(c)- activity and astrocytes are necessary for interleukin-1 beta-mediated hypoxic neuronal injury (English)

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7 January 2020

1 reference

1

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7 January 2020

Sandra J. Hewett

5

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7 January 2020

author name string

Jun Li

2

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7 January 2020

Doug Lobner

3

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7 January 2020

Louise D McCullough

4

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7 January 2020

publication date

1 September 2007

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7 January 2020

published in

Journal of Neuroscience

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7 January 2020

volume

27

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7 January 2020

issue

38

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7 January 2020

page(s)

10094-10105

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Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins

7 January 2020

cites work

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12 December 2020

Tripartite synapses: glia, the unacknowledged partner

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12 December 2020

Expression and localization of p80 and p68 interleukin-1 receptor proteins in the brain of adult mice

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12 December 2020

The interleukin-1 type I receptor is expressed in human hypothalamus.

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12 December 2020

Glioma cells release excitotoxic concentrations of glutamate.

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12 December 2020

Attenuation of temporary focal cerebral ischemic injury in the mouse following transfection with interleukin-1 receptor antagonist

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12 December 2020

Mice deficient in interleukin-1 converting enzyme are resistant to neonatal hypoxic-ischemic brain damage

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12 December 2020

Is CREB a key to neuronal survival?

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12 December 2020

Cyclooxygenase-2 contributes to N-methyl-D-aspartate-mediated neuronal cell death in primary cortical cell culture

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12 December 2020

Cortical cell death induced by IL-1 is mediated via actions in the hypothalamus of the rat

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12 December 2020

A microtiter trypan blue absorbance assay for the quantitative determination of excitotoxic neuronal injury in cell culture.

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12 December 2020

Activation of microglia by secreted amyloid precursor protein evokes release of glutamate by cystine exchange and attenuates synaptic function.

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12 December 2020

Cytokines regulate expression of the type 1 interleukin-1 receptor in rat hippocampal neurons and glia

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12 December 2020

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12 December 2020

Dibutyryl-cAMP (dbcAMP) up-regulates astrocytic chloride-dependent L-[3H]glutamate transport and expression of both system xc(-) subunits

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12 December 2020

Role of IL-1alpha and IL-1beta in ischemic brain damage.

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12 December 2020

Oxidative glutamate toxicity can be a component of the excitotoxicity cascade.

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12 December 2020

SIN-1-induced cytotoxicity in mixed cortical cell culture: peroxynitrite-dependent and -independent induction of excitotoxic cell death.

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12 December 2020

Interleukin-1 influences ischemic brain damage in the mouse independently of the interleukin-1 type I receptor.

1 reference

12 December 2020

The novel and systemically active metabotropic glutamate 1 (mGlu1) receptor antagonist 3-MATIDA reduces post-ischemic neuronal death

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12 December 2020

Knockout mice: simple solutions to the problems of genetic background and flanking genes

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12 December 2020

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12 December 2020

The origin and neuronal function of in vivo nonsynaptic glutamate.

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12 December 2020

Expression of interleukin-1 receptors and their role in interleukin-1 actions in murine microglial cells

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12 December 2020

Suppression of oxidative neuronal damage after transient middle cerebral artery occlusion in mice lacking interleukin-1.

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12 December 2020

Interleukin-1β protects neurons via the interleukin-1 (IL-1) receptor-mediated Akt pathway and by IL-1 receptor-independent decrease of transmembrane currents in vivo

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12 December 2020

Interleukin 1beta modulates rat subfornical organ neurons as a result of activation of a non-selective cationic conductance

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12 December 2020

Delayed administration of interleukin-1 receptor antagonist protects against transient cerebral ischaemia in the rat.

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12 December 2020

Glutamate uptake disguises neurotoxic potency of glutamate agonists in cerebral cortex in dissociated cell culture

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12 December 2020

Interleukin-1 receptor antagonist inhibits ischaemic and excitotoxic neuronal damage in the rat

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12 December 2020

Activation of stimulatory heterotrimeric G proteins increases glutathione and protects neuronal cells against oxidative stress

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12 December 2020

Type I interleukin-1 receptors in the mouse brain-endocrine-immune axis labelled with [125I]recombinant human interleukin-1 receptor antagonist.

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12 December 2020

Inhibition of non‐vesicular glutamate release by group III metabotropic glutamate receptors in the nucleus accumbens

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12 December 2020

Neuroprotective function of the PGE2 EP2 receptor in cerebral ischemia.

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12 December 2020

Cell type-specific interleukin-1beta signaling in the CNS.

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12 December 2020

Enhanced release of synaptic glutamate underlies the potentiation of oxygen-glucose deprivation-induced neuronal injury after induction of NOS-2.

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12 December 2020

Transcriptional control of cystine/glutamate transporter gene by amino acid deprivation

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12 December 2020

Interleukin-1 and the interleukin-1 type 1 receptor are essential for the progressive neurodegeneration that ensues subsequent to a mild hypoxic/ischemic injury.

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12 December 2020

Interleukin-1beta potentiates neuronal injury in a variety of injury models involving energy deprivation

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12 December 2020

Changes in secondary glutamate release underlie the developmental regulation of excitotoxic neuronal cell death.

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12 December 2020

Inhibition of cystine uptake disrupts the growth of primary brain tumors

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12 December 2020

A randomised phase II study of interleukin-1 receptor antagonist in acute stroke patients

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12 December 2020

Gene regulation by IL-1beta independent of IL-1R1 in the mouse brain.

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12 December 2020

Distribution of the cystine/glutamate antiporter system xc- in the brain, kidney, and duodenum

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12 December 2020

System Xc- and apolipoprotein E expressed by microglia have opposite effects on the neurotoxicity of amyloid-beta peptide 1-40.

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12 December 2020

The tripartite synapse: roles for gliotransmission in health and disease

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12 December 2020

Induction of interleukin-1 beta mRNA in rat brain after transient forebrain ischemia.

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12 December 2020

Selective dysfunction of hippocampal CA1 astrocytes contributes to delayed neuronal damage after transient forebrain ischemia

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12 December 2020

Oxygen radical mechanisms of brain injury following ischemia and reperfusion

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12 December 2020

Phylogenetic studies on the synaptic vesicle glutamate transport system.

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12 December 2020

Immature cortical neurons are uniquely sensitive to glutamate toxicity by inhibition of cystine uptake

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12 December 2020

Role of amino acid transport and countertransport in nutrition and metabolism

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12 December 2020

Reversible middle cerebral artery occlusion without craniectomy in rats

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12 December 2020

Quantitative determination of glutamate mediated cortical neuronal injury in cell culture by lactate dehydrogenase efflux assay

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12 December 2020

N-methyl-D-aspartate receptors mediate hypoxic neuronal injury in cortical culture

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12 December 2020

Visualization and characterization of interleukin 1 receptors in brain

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12 December 2020

Oxygen free radical involvement in ischemia and reperfusion injury to brain

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12 December 2020

Characterization of L-glutamate uptake into and release from astrocytes and neurons cultured from different brain regions

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12 December 2020

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12 December 2020

Elevation of the Extracellular Concentrations of Glutamate and Aspartate in Rat Hippocampus During Transient Cerebral Ischemia Monitored by Intracerebral Microdialysis

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12 December 2020

Expression of type I interleukin-1 receptor mRNA and its regulation in cultured astrocytes.

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12 December 2020

Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion.

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12 December 2020

Localization of interleukin 1 type I receptor mRNA in rat brain.

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12 December 2020

Interferon-gamma and interleukin-1 beta induce nitric oxide formation from primary mouse astrocytes

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12 December 2020

Glutamate transporters in glial plasma membranes: highly differentiated localizations revealed by quantitative ultrastructural immunocytochemistry

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12 December 2020

Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats

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12 December 2020

Interleukin-1 receptor antagonist inhibits neuronal damage caused by fluid percussion injury in the rat.

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12 December 2020

Attenuation of stroke size in rats using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist in brain

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12 December 2020

An in situ hybridization study on interleukin-1β mRNA induced by transient forebrain ischemia in the rat brain

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12 December 2020

The interleukin-1 receptor antagonist (rhIL-1ra) protects against cerebral infarction in a rat model of hypoxia-ischemia

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12 December 2020

Vitamin E, ascorbate, glutathione, glutathione disulfide, and enzymes of glutathione metabolism in cultures of chick astrocytes and neurons: evidence that astrocytes play an important role in antioxidative processes in the brain

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12 December 2020

Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1.

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12 December 2020

Induction of interleukin-1 beta mRNA after focal cerebral ischaemia in the rat.

1 reference

12 December 2020

Dipyridamole increases oxygen-glucose deprivation-induced injury in cortical cell culture

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12 December 2020

Interleukin-1 beta mRNA expression in ischemic rat cortex

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12 December 2020

Interleukin 1 signaling occurs exclusively via the type I receptor

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12 December 2020

Interleukin-1 receptor antagonist

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12 December 2020

Effect of brain edema on infarct volume in a focal cerebral ischemia model in rats

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12 December 2020

Progression from ischemic injury to infarct following middle cerebral artery occlusion in the rat.

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12 December 2020

Interleukin-1 binding sites on astrocytes

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12 December 2020

Mitochondrial generation of reactive oxygen species after brain ischemia in the rat.

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12 December 2020

Very delayed infarction after mild focal cerebral ischemia: a role for apoptosis?

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12 December 2020

Peripheral administration of Interleukin-1 Receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat.

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12 December 2020

Early increases in TNF-alpha, IL-6 and IL-1 beta levels following transient cerebral ischemia in gerbil brain.

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12 December 2020

Potentiation of oxygen-glucose deprivation-induced neuronal death after induction of iNOS.

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12 December 2020

Neuroprotective effects of human recombinant interleukin-1 receptor antagonist in focal cerebral ischaemia in the rat.

1 reference

12 December 2020

Knockout of glutamate transporters reveals a major role for astroglial transport in excitotoxicity and clearance of glutamate

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12 December 2020

Overexpression of interleukin-1 receptor antagonist in the mouse brain reduces ischemic brain injury

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12 December 2020

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) decreases glutamate uptake in cultured astrocytes

1 reference

12 December 2020

Expression of a dominant negative mutant of interleukin-1 beta converting enzyme in transgenic mice prevents neuronal cell death induced by trophic factor withdrawal and ischemic brain injury

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12 December 2020

Attenuation of transient focal cerebral ischemic injury in transgenic mice expressing a mutant ICE inhibitory protein.

1 reference

12 December 2020

Enlargement of human cerebral ischemic lesion volumes measured by diffusion-weighted magnetic resonance imaging.

1 reference

12 December 2020

Evidence against a permissive role of the metabotropic glutamate receptor 1 in acute excitotoxicity.

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12 December 2020

Glutamate transport and metabolism in astrocytes.

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12 December 2020

Phenotypic and functional characterization of mice that lack the type I receptor for IL-1

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12 December 2020

Global forebrain ischemia results in differential cellular expression of interleukin-1beta (IL-1beta) and its receptor at mRNA and protein level.

1 reference

12 December 2020

Delayed reduction of ischemic brain injury and neurological deficits in mice lacking the inducible nitric oxide synthase gene.

1 reference

12 December 2020

Antioxidant defense of the brain: a role for astrocytes

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12 December 2020

Characterization of multiple cysteine and cystine transporters in rat alveolar type II cells

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12 December 2020

Utilization of cysteine and cysteine precursors for the synthesis of glutathione in astroglial cultures: preference for cystine.

1 reference

12 December 2020

Reduced ischemic brain injury in interleukin-1 beta converting enzyme-deficient mice.

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12 December 2020

Cerebral vessels express interleukin 1beta after focal cerebral ischemia.

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12 December 2020

Middle cerebral artery occlusion in the rat causes a biphasic production of immunoreactive interleukin-1beta in the cerebral cortex

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12 December 2020

Exacerbation of ischemic brain damage by localized striatal injection of interleukin-1beta in the rat.

1 reference

12 December 2020

Attenuation of ischemic inflammatory response in mouse brain using an adenoviral vector to induce overexpression of interleukin-1 receptor antagonist

1 reference

12 December 2020

Interleukin-1beta and the interleukin-1 receptor antagonist act in the striatum to modify excitotoxic brain damage in the rat.

1 reference

12 December 2020

Time course of lesion development in patients with acute stroke: serial diffusion- and hemodynamic-weighted magnetic resonance imaging

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12 December 2020

The progression and topographic distribution of interleukin-1beta expression after permanent middle cerebral artery occlusion in the rat.

1 reference

12 December 2020

10.1523/JNEUROSCI.2459-07.2007

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881516%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17881516%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

PubMed publication ID

17881516

1 reference