(Q27473236)

English

Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus

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scholarly article

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Selection and Characterization of Replicon Variants Dually Resistant to Thumb- and Palm-Binding Nonnucleoside Polymerase Inhibitors of the Hepatitis C Virus (English)

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Hepatitis C virus

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based on heuristic

inferred from title

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based on heuristic

inferred from title

author name string

Sophie Le Pogam

1

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Hyunsoon Kang

2

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Seth F Harris

3

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Vincent Leveque

4

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Anthony M Giannetti

5

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Samir Ali

6

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Wen-Rong Jiang

7

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Sonal Rajyaguru

8

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Gisele Tavares

9

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Connie Oshiro

10

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Than Hendricks

11

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Klaus Klumpp

12

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Julian Symons

13

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Michelle F Browner

14

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Nick Cammack

15

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Isabel Nájera

16

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publication date

June 2006

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Journal of Virology

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80

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12

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6146-54

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Mutations conferring resistance to a hepatitis C virus (HCV) RNA-dependent RNA polymerase inhibitor alone or in combination with an HCV serine protease inhibitor in vitro

1 reference

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21 March 2017

Wide range of quasispecies diversity during primary hepatitis C virus infection

1 reference

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Resistance Profile of a Hepatitis C Virus RNA-Dependent RNA Polymerase Benzothiadiazine Inhibitor

1 reference

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Crystallographic Identification of a Noncompetitive Inhibitor Binding Site on the Hepatitis C Virus NS5B RNA Polymerase Enzyme

1 reference

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1 reference

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Viral and Cellular Determinants of Hepatitis C Virus RNA Replication in Cell Culture

1 reference

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Non-nucleoside analogue inhibitors bind to an allosteric site on HCV NS5B polymerase. Crystal structures and mechanism of inhibition

1 reference

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Crystal structures of active and inactive conformations of a caliciviral RNA-dependent RNA polymerase

1 reference

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Enhancement of hepatitis C virus RNA replication by cell culture-adaptive mutations

1 reference

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Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site

1 reference

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Structure of the RNA-dependent RNA polymerase of poliovirus

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Likelihood-enhanced fast translation functions

1 reference

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Coot: model-building tools for molecular graphics

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Refinement of macromolecular structures by the maximum-likelihood method

1 reference

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The CCP4 suite: programs for protein crystallography

1 reference

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Peginterferon alfa-2a plus ribavirin for chronic hepatitis C virus infection

1 reference

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Peginterferon alfa-2b plus ribavirin compared with interferon alfa-2b plus ribavirin for initial treatment of chronic hepatitis C: a randomised trial

1 reference

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Genetic diversity and evolution of hepatitis C virus--15 years on

1 reference

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Epidemiology of hepatitis C: geographic differences and temporal trends

1 reference

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In vitro selected Con1 subgenomic replicons resistant to 2'-C-methyl-cytidine or to R1479 show lack of cross resistance

1 reference

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Bioinformatics approach to predicting HIV drug resistance

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3-(1,1-dioxo-2H-(1,2,4)-benzothiadiazin-3-yl)-4-hydroxy-2(1H)-quinolinones, potent inhibitors of hepatitis C virus RNA-dependent RNA polymerase

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1 reference

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Binding site characterization and resistance to a class of non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase

1 reference

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Crystal structures of the RNA-dependent RNA polymerase genotype 2a of hepatitis C virus reveal two conformations and suggest mechanisms of inhibition by non-nucleoside inhibitors

1 reference

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Inhibition of native hepatitis C virus replicase by nucleotide and non-nucleoside inhibitors.

1 reference

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Non-nucleoside inhibitors of the HCV polymerase

1 reference

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1 reference

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Characterization of the inhibition of hepatitis C virus RNA replication by nonnucleosides.

1 reference

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Non-nucleoside inhibitors of the hepatitis C virus NS5B polymerase: discovery and preliminary SAR of benzimidazole derivatives

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HIV chemotherapy

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The quasispecies (extremely heterogeneous) nature of viral RNA genome populations: biological relevance--a review

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Interdomain communication in hepatitis C virus polymerase abolished by small molecule inhibitors bound to a novel allosteric site

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Processing of X-ray diffraction data collected in oscillation mode

1 reference

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.02628-05

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