(Q27548232)

English

Polyubiquitin-binding protein UFD1 YGR048W

fungal protein found in Saccharomyces cerevisiae S288c

UFD1
YGR048W
polyubiquitin-binding protein UFD1

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Statements

1 reference

25 May 2022

1 reference

19 January 2017

Ubiquitin fusion degradation protein Ufd1-like

1 reference

stated in

InterPro Release 71.0

reference URL

http://www.ebi.ac.uk/interpro/protein/P53044

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

polyubiquitin modification-dependent protein binding

1 reference

9 May 2019

Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

1 reference

9 May 2019

Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

12 references

9 May 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

An in vivo map of the yeast protein interactome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

A comprehensive two-hybrid analysis to explore the yeast protein interactome

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

Functional organization of the yeast proteome by systematic analysis of protein complexes

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

Role of Cdc48/p97 as a SUMO-targeted segregase curbing Rad51-Rad52 interaction

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

Proteome survey reveals modularity of the yeast cell machinery

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

A comprehensive analysis of protein-protein interactions in Saccharomyces cerevisiae

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

Key steps in ERAD of luminal ER proteins reconstituted with purified components

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

The Cdc48 ATPase modulates the interaction between two proteolytic factors Ufd2 and Rad23.

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

9 May 2019

A stress-responsive system for mitochondrial protein degradation

GOA

curator

IntAct protein interaction database

reference URL

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

1 reference

9 May 2019

A ribosome-bound quality control complex triggers degradation of nascent peptides and signals translation stress

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

1 reference

10 September 2018

Mobilization of processed, membrane-tethered SPT23 transcription factor by CDC48(UFD1/NPL4), a ubiquitin-selective chaperone

http://www.ebi.ac.uk/QuickGO/annotations?protein=P53044&geneProductId=UniProtKB:P53044

1 reference

9 May 2019

One library to make them all: streamlining the creation of yeast libraries via a SWAp-Tag strategy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

HDA

biological process

ubiquitin-dependent ERAD pathway

1 reference

9 May 2019

HRD4/NPL4 is required for the proteasomal processing of ubiquitinated ER proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

nonfunctional rRNA decay

1 reference

9 May 2019

40S subunit dissociation and proteasome-dependent RNA degradation in nonfunctional 25S rRNA decay

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

ubiquitin-dependent protein catabolic process

1 reference

9 May 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IEA

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

9 May 2019

The Cdc48-Ufd1-Npl4 complex is central in ubiquitin-proteasome triggered catabolite degradation of fructose-1,6-bisphosphatase

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

negative regulation of telomerase activity

1 reference

9 May 2019

Proteomics of yeast telomerase identified Cdc48-Npl4-Ufd1 and Ufd4 as regulators of Est1 and telomere length

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

cytoplasm protein quality control by the ubiquitin-proteasome system

1 reference

9 May 2019

Degradation of a cytosolic protein requires endoplasmic reticulum-associated degradation machinery.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

ribosome-associated ubiquitin-dependent protein catabolic process

1 reference

9 May 2019

Cdc48/p97 promotes degradation of aberrant nascent polypeptides bound to the ribosome

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

protein localization to vacuole

1 reference

9 May 2019

Cdc48 and ubiquilins confer selective anterograde protein sorting and entry into the multivesicular body in yeast.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

mitochondria-associated ubiquitin-dependent protein catabolic process

1 reference

9 May 2019

Doa1 targets ubiquitinated substrates for mitochondria-associated degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:P53044

determination method

IMP

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

Saccharomyces Genome Database ID

1 reference

20 March 2022

(Q27548232)

Polyubiquitin-binding protein UFD1 YGR048W

Statements

Identifiers

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