Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q27934285)
Watch
English
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
PubMed
PubMed ID
18407841
retrieved
1 December 2016
title
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p
(English)
1 reference
stated in
PubMed
PubMed ID
18407841
retrieved
1 December 2016
main subject
biophysics
0 references
cell biology
0 references
structural biology
0 references
Protein phosphatase regulator SHP1 YBL058W
1 reference
stated in
GOA release 2020-03-11
Dfm1p YDR411C
1 reference
stated in
GOA release 2020-03-11
AAA family ATPase CDC48 YDL126C
1 reference
stated in
GOA release 2020-03-11
Derlin YBR201W
1 reference
stated in
GOA release 2020-03-11
Ubx7p YBR273C
1 reference
stated in
GOA release 2020-03-11
Usa1p YML029W
1 reference
stated in
GOA release 2020-03-11
Ubiquitin ligase complex subunit HRD3 YLR207W
1 reference
stated in
GOA release 2020-03-11
E3 ubiquitin-protein ligase HRD1 YOL013C
1 reference
stated in
GOA release 2020-03-11
Polyubiquitin-binding protein UFD1 YGR048W
1 reference
stated in
GOA release 2020-03-11
author
Tom Rapoport
series ordinal
3
object named as
Tom A Rapoport
0 references
Veit Goder
object named as
Veit Goder
series ordinal
1
0 references
Pedro Carvalho
object named as
Pedro Carvalho
series ordinal
2
0 references
language of work or name
English
0 references
publication date
14 May 2008
0 references
published in
FEBS Letters
1 reference
stated in
PubMed
PubMed ID
18407841
retrieved
1 December 2016
volume
582
0 references
page(s)
1575-80
0 references
issue
11
0 references
cites work
Yeast Derlin Dfm1 interacts with Cdc48 and functions in ER homeostasis
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Ubx2 links the Cdc48 complex to ER-associated protein degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Membrane-bound Ubx2 recruits Cdc48 to ubiquitin ligases and their substrates to ensure efficient ER-associated protein degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Yos9 protein is essential for degradation of misfolded glycoproteins and may function as lectin in ERAD.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Exploration of the topological requirements of ERAD identifies Yos9p as a lectin sensor of misfolded glycoproteins in the ER lumen
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Shp1 and Ubx2 are adaptors of Cdc48 involved in ubiquitin-dependent protein degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
A membrane protein required for dislocation of misfolded proteins from the ER
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
The UBX domain: a widespread ubiquitin-like module
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
A complex of mammalian ufd1 and npl4 links the AAA-ATPase, p97, to ubiquitin and nuclear transport pathways
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
ERAD: the long road to destruction
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
The p47 co-factor regulates the ATPase activity of the membrane fusion protein, p97
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
p47 is a cofactor for p97-mediated membrane fusion
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
20 March 2017
Structural insights into the p97-Ufd1-Npl4 complex.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
29 September 2017
Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2438607
retrieved
29 September 2017
Distinct AAA-ATPase p97 complexes function in discrete steps of nuclear assembly.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.03.056
retrieved
21 January 2018
A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.03.056
retrieved
21 January 2018
The AAA ATPase p97/VCP interacts with its alternative co-factors, Ufd1-Npl4 and p47, through a common bipartite binding mechanism
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.03.056
retrieved
21 January 2018
Cdc48 (p97): a "molecular gearbox" in the ubiquitin pathway?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FJ.FEBSLET.2008.03.056
retrieved
21 January 2018
Identifiers
DOI
10.1016/J.FEBSLET.2008.03.056
0 references
Fatcat ID
release_wpbwxxegrzeorpuzkalvhlslv4
1 reference
stated in
Fatcat
reference URL
https://api.fatcat.wiki/v0/release/wpbwxxegrzeorpuzkalvhlslv4
retrieved
24 November 2022
based on heuristic
mapped directly with Wikidata item
PMCID
2438607
0 references
PubMed ID
18407841
1 reference
stated in
PubMed
PubMed ID
18407841
retrieved
1 December 2016
ResearchGate publication ID
5444525
0 references
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
