(Q27553152)

http://www.ebi.ac.uk/interpro/protein/Q05787

membrane protein

1 reference

based on heuristic

inferred from GOA cell component → membrane

Endoplasmic Reticular Retrotranslocon

1 reference

Transporter Classification Database ID

3.A.16.1.2

retrieved

2 October 2019

based on heuristic

hierarchical database ID heuristic

found in taxon

Saccharomyces cerevisiae S288c

1 reference

25 May 2022

1 reference

25 May 2022

ubiquitin-protein transferase activity

1 reference

14 February 2019

In vivo action of the HRD ubiquitin ligase complex: mechanisms of endoplasmic reticulum quality control and sterol regulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

9 references

14 February 2019

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

Sec61p is part of the endoplasmic reticulum-associated degradation machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

Proteome survey reveals modularity of the yeast cell machinery

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

14 February 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

luminal surveillance complex

IPI

cell component

1 reference

14 February 2019

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

Hrd1p ubiquitin ligase ERAD-M complex

1 reference

14 February 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

integral component of membrane

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

1 reference

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

Hrd1p ubiquitin ligase ERAD-L complex

IEA

1 reference

14 February 2019

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q05787&geneProductId=UniProtKB:Q05787

endoplasmic reticulum

1 reference

7 November 2018

ubiquitin-dependent ERAD pathway

IEA

biological process

1 reference

14 February 2019

An HRD/DER-independent ER quality control mechanism involves Rsp5p-dependent ubiquitination and ER-Golgi transport

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

retrograde protein transport, ER to cytosol

1 reference

14 February 2019

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

IMP

protein ubiquitination

1 reference

14 February 2019

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q05787

IEA

Identifiers

1 reference

20 March 2022

1 reference

25 May 2022

1 reference