(Q27930621)

1 December 2016

title

Sec61p is part of the endoplasmic reticulum-associated degradation machinery (English)

1 reference

Translocon subunit SEC61 YLR378C

1 December 2016

main subject

endoplasmic reticulum

0 references

1 reference

AAA family ATPase CDC48 YDL126C

1 reference

Ubiquitin ligase complex subunit HRD3 YLR207W

1 reference

E3 ubiquitin-protein ligase HRD1 YOL013C

1 reference

Carboxypeptidase C PRC1 YMR297W

1 reference

author name string

Dieter H Wolf

series ordinal

2

0 references

Antje Schäfer

series ordinal

1

0 references

language of work or name

English

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publication date

7 October 2009

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1 reference

describes a project that uses

1 December 2016

volume

28

0 references

issue

19

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page(s)

2874-84

0 references

ImageJ

1 reference

Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2760108/fullTextXML

inferred from PubMed Central ID database lookup

cites work

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One step at a time: endoplasmic reticulum-associated degradation

20 March 2017

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Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

20 March 2017

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A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

20 March 2017

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The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

20 March 2017

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Yos9p detects and targets misfolded glycoproteins for ER-associated degradation

20 March 2017

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Distinct machinery is required in Saccharomyces cerevisiae for the endoplasmic reticulum-associated degradation of a multispanning membrane protein and a soluble luminal protein

20 March 2017

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A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

20 March 2017

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A membrane protein required for dislocation of misfolded proteins from the ER

20 March 2017

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A genomic screen identifies Dsk2p and Rad23p as essential components of ER-associated degradation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

20 March 2017

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Coordination of N-glycosylation and protein translocation across the endoplasmic reticulum membrane by Sss1 protein.

20 March 2017

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Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

20 March 2017

1 reference

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AAA-ATPase p97/Cdc48p, a cytosolic chaperone required for endoplasmic reticulum-associated protein degradation

20 March 2017

1 reference

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The AAA ATPase Cdc48/p97 and its partners transport proteins from the ER into the cytosol

20 March 2017

1 reference

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Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

20 March 2017

1 reference

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Membrane topology and function of Der3/Hrd1p as a ubiquitin-protein ligase (E3) involved in endoplasmic reticulum degradation

20 March 2017

1 reference

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BiP acts as a molecular ratchet during posttranslational transport of prepro-alpha factor across the ER membrane

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Sec61p serves multiple roles in secretory precursor binding and translocation into the endoplasmic reticulum membrane

20 March 2017

1 reference

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Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Sec61p mediates export of a misfolded secretory protein from the endoplasmic reticulum to the cytosol for degradation

20 March 2017

1 reference

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Sec61-mediated transfer of a membrane protein from the endoplasmic reticulum to the proteasome for destruction

20 March 2017

1 reference

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ER degradation of a misfolded luminal protein by the cytosolic ubiquitin-proteasome pathway

20 March 2017

1 reference

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Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Early stages in the yeast secretory pathway are required for transport of carboxypeptidase Y to the vacuole

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

ERAD: the long road to destruction

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Protein folding and misfolding

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Mutant analysis links the translocon and BiP to retrograde protein transport for ER degradation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Cotranslocational degradation protects the stressed endoplasmic reticulum from protein overload

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Sec61p is required for ERAD-L: genetic dissection of the translocation and ERAD-L functions of Sec61P using novel derivatives of CPY.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Protein translocation by the Sec61/SecY channel

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Endoplasmic reticulum-associated degradation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

For whom the bell tolls: protein quality control of the endoplasmic reticulum and the ubiquitin-proteasome connection

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

ER-golgi traffic is a prerequisite for efficient ER degradation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Complexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Role of the ubiquitin-selective CDC48(UFD1/NPL4 )chaperone (segregase) in ERAD of OLE1 and other substrates

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Traffic jam: a compendium of human diseases that affect intracellular transport processes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Surfing the Sec61 channel: bidirectional protein translocation across the ER membrane.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Retrograde protein translocation: ERADication of secretory proteins in health and disease

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Endoplasmic reticulum degradation of a mutated ATP-binding cassette transporter Pdr5 proceeds in a concerted action of Sec61 and the proteasome.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Signal sequences specify the targeting route to the endoplasmic reticulum membrane

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

A nascent secretory protein may traverse the ribosome/endoplasmic reticulum translocase complex as an extended chain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Protein transport across the endoplasmic reticulum membrane

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2760108

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.231

Ubiquitin ligase Hul5 is required for fragment-specific substrate degradation in endoplasmic reticulum-associated degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.231

Co-translational interactions of apoprotein B with the ribosome and translocon during lipoprotein assembly or targeting to the proteasome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.231

Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.231

Identification of SEC12, SED4, Truncated SEC16, and EKS1/HRD3 as Multicopy Suppressors of ts Mutants of Sari GTPase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOJ.2009.231

Re-entering the translocon from the lumenal side of the endoplasmic reticulum. Studies on mutated carboxypeptidase yscY species

21 January 2018

1 reference

12 December 2020

Characterization of the proteasome interaction with the Sec61 channel in the endoplasmic reticulum

1 reference

12 December 2020

Genetic interactions of Hrd3p and Der3p/Hrd1p with Sec61p suggest a retro-translocation complex mediating protein transport for ER degradation

1 reference

12 December 2020

Synthesis and processing of in vitro and in vivo precursors of the vacuolar yeast enzyme carboxypeptidase Y

1 reference

12 December 2020

Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease

1 reference

12 December 2020

Identifiers

DOI

10.1038/EMBOJ.2009.231

0 references

PMC publication ID

2760108

0 references

1 reference