(Q27938831)

1 December 2016

title

Der1 promotes movement of misfolded proteins through the endoplasmic reticulum membrane (English)

1 reference

Ubiquitin ligase complex subunit HRD3 YLR207W

1 December 2016

main subject

endoplasmic reticulum

0 references

1 reference

Yos9p YDR057W

1 reference

E3 ubiquitin-protein ligase HRD1 YOL013C

1 reference

Derlin YBR201W

1 reference

author

Ernst Jarosch

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

author name string

Martin Mehnert

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

Thomas Sommer

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

language of work or name

English

0 references

publication date

January 2014

0 references

2 references

1 December 2016

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

volume

16

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

9 June 2020

page(s)

77-86

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

The ubiquitylation machinery of the endoplasmic reticulum

9 June 2020

cites work

1 reference

Cleaning up: ER-associated degradation to the rescue

21 January 2018

1 reference

Loss of HRD1-mediated protein degradation causes amyloid precursor protein accumulation and amyloid-beta generation

21 January 2018

1 reference

An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid beta-protein

21 January 2018

1 reference

Huntingtin interacts with the cue domain of gp78 and inhibits gp78 binding to ubiquitin and p97/VCP.

21 January 2018

1 reference

CFTR: folding, misfolding and correcting the ΔF508 conformational defect.

21 January 2018

1 reference

ERAD ubiquitin ligases: multifunctional tools for protein quality control and waste disposal in the endoplasmic reticulum

21 January 2018

1 reference

Der3p/Hrd1p is required for endoplasmic reticulum-associated degradation of misfolded lumenal and integral membrane proteins

21 January 2018

1 reference

Hrd1p/Der3p is a membrane-anchored ubiquitin ligase required for ER-associated degradation.

21 January 2018

1 reference

Yos9p detects and targets misfolded glycoproteins for ER-associated degradation

21 January 2018

1 reference

The Hrd1p ligase complex forms a linchpin between ER-lumenal substrate selection and Cdc48p recruitment

21 January 2018

1 reference

A complex of Yos9p and the HRD ligase integrates endoplasmic reticulum quality control into the degradation machinery.

21 January 2018

1 reference

Usa1 functions as a scaffold of the HRD-ubiquitin ligase.

21 January 2018

1 reference

A luminal surveillance complex that selects misfolded glycoproteins for ER-associated degradation

21 January 2018

1 reference

Der1p, a protein required for degradation of malfolded soluble proteins of the endoplasmic reticulum: topology and Der1-like proteins

21 January 2018

1 reference

Use of modular substrates demonstrates mechanistic diversity and reveals differences in chaperone requirement of ERAD.

21 January 2018

1 reference

Misfolded proteins are sorted by a sequential checkpoint mechanism of ER quality control

21 January 2018

1 reference

Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p

21 January 2018

1 reference

Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation

21 January 2018

1 reference

Ubiquitination is required for the retro-translocation of a short-lived luminal endoplasmic reticulum glycoprotein to the cytosol for degradation by the proteasome

21 January 2018

1 reference

The role of multiubiquitination in dislocation and degradation of the alpha subunit of the T cell antigen receptor

21 January 2018

1 reference

Protein dislocation from the ER requires polyubiquitination and the AAA-ATPase Cdc48.

21 January 2018

1 reference

Finding the will and the way of ERAD substrate retrotranslocation

21 January 2018

1 reference

Protein dislocation from the ER.

21 January 2018

1 reference

Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins

21 January 2018

1 reference

The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p

21 January 2018

1 reference

A regulatory link between ER-associated protein degradation and the unfolded-protein response

21 January 2018

1 reference

Functional and genomic analyses reveal an essential coordination between the unfolded protein response and ER-associated degradation

21 January 2018

1 reference

Recognition of an ERAD-L substrate analyzed by site-specific in vivo photocrosslinking

21 January 2018

1 reference

Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum

21 January 2018

1 reference

Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein

21 January 2018

1 reference

An expanded eukaryotic genetic code

21 January 2018

1 reference

An improved system for the generation and analysis of mutant proteins containing unnatural amino acids in Saccharomyces cerevisiae.

21 January 2018

1 reference

Molecular chaperones in the yeast endoplasmic reticulum maintain the solubility of proteins for retrotranslocation and degradation

21 January 2018

1 reference

Protein translocation across the eukaryotic endoplasmic reticulum and bacterial plasma membranes

21 January 2018

1 reference

A membrane protein required for dislocation of misfolded proteins from the ER

21 January 2018

1 reference

Derlin-1 promotes the efficient degradation of the cystic fibrosis transmembrane conductance regulator (CFTR) and CFTR folding mutants

21 January 2018

1 reference

Recruitment of the p97 ATPase and ubiquitin ligases to the site of retrotranslocation at the endoplasmic reticulum membrane

21 January 2018

1 reference

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane

21 January 2018

1 reference

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation

21 January 2018

1 reference

Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.

21 January 2018

1 reference

A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol

21 January 2018

1 reference

Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

21 January 2018

1 reference

Cdc48: a power machine in protein degradation

21 January 2018

1 reference

Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase

21 January 2018

1 reference

Epitope tagging of yeast genes using a PCR-based strategy: more tags and improved practical routines

21 January 2018

1 reference

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

21 January 2018

1 reference

Role of Cue1p in ubiquitination and degradation at the ER surface

21 January 2018

1 reference

Sec61p-independent degradation of the tail-anchored ER membrane protein Ubc6p

21 January 2018

1 reference

Der1, a novel protein specifically required for endoplasmic reticulum degradation in yeast

21 January 2018

1 reference

12 December 2020

Degradation of subunits of the Sec61p complex, an integral component of the ER membrane, by the ubiquitin-proteasome pathway.

1 reference

12 December 2020

Cystic fibrosis: premature degradation of mutant proteins as a molecular disease mechanism

1 reference

12 December 2020

Additional modules for versatile and economical PCR-based gene deletion and modification in Saccharomyces cerevisiae

1 reference

12 December 2020

Identifiers

DOI

10.1038/NCB2882

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:24292014%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 June 2020

1024073539

0 references

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017