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Cleaning up: ER-associated degradation to the rescue
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instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
review article
1 reference
stated in
Europe PubMed Central
title
Cleaning up: ER-associated degradation to the rescue
(English)
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
author name string
Jeffrey L Brodsky
series ordinal
1
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
language of work or name
English
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publication date
1 December 2012
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
published in
Cell
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stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
volume
151
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
issue
6
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
page(s)
1163-1167
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stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
cites work
Aberrant substrate engagement of the ER translocon triggers degradation by the Hrd1 ubiquitin ligase.
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PubMed Central
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retrieved
30 September 2017
The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology
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PubMed Central
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retrieved
30 September 2017
Requirements for Efficient Correction of ΔF508 CFTR Revealed by Analyses of Evolved Sequences
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
CFTR: folding, misfolding and correcting the ΔF508 conformational defect.
1 reference
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PubMed Central
reference URL
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retrieved
30 September 2017
Protein quality control in the ER: balancing the ubiquitin checkbook
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
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30 September 2017
Correction of the F508del-CFTR protein processing defect in vitro by the investigational drug VX-809.
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PubMed Central
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30 September 2017
Bypass of glycan-dependent glycoprotein delivery to ERAD by up-regulated EDEM1.
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30 September 2017
Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum
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PubMed Central
reference URL
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30 September 2017
Cdc48: a power machine in protein degradation
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PubMed Central
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30 September 2017
A ubiquitin ligase-associated chaperone holdase maintains polypeptides in soluble states for proteasome degradation
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PubMed Central
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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
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30 September 2017
Protein folding and modification in the mammalian endoplasmic reticulum.
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PubMed Central
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30 September 2017
Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5
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PubMed Central
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30 September 2017
Retrotranslocation of a misfolded luminal ER protein by the ubiquitin-ligase Hrd1p
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PubMed Central
reference URL
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30 September 2017
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis.
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PubMed Central
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30 September 2017
Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from endoplasmic reticulum membranes into the cytosol through a subcellular compartment resembling lipid droplets
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
ERAD substrate recognition in budding yeast
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Usa1 functions as a scaffold of the HRD-ubiquitin ligase.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
N-glycan structures: recognition and processing in the ER.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Sec61p is part of the endoplasmic reticulum-associated degradation machinery
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Misfolded membrane proteins are specifically recognized by the transmembrane domain of the Hrd1p ubiquitin ligase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Dissecting the ER-associated degradation of a misfolded polytopic membrane protein
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
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30 September 2017
The biological and chemical basis for tissue-selective amyloid disease
1 reference
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PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
30 September 2017
Correction of both NBD1 energetics and domain interface is required to restore ΔF508 CFTR folding and function
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
28 June 2018
Characterization of an ERAD pathway for nonglycosylated BiP substrates, which require Herp
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
28 June 2018
Role of the SEL1L:LC3-I complex as an ERAD tuning receptor in the mammalian ER.
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
21 September 2018
Protein unfolding is not a prerequisite for endoplasmic reticulum-to-cytosol dislocation
1 reference
stated in
PubMed Central
reference URL
https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3521611
retrieved
21 September 2018
Identifiers
DOI
10.1016/J.CELL.2012.11.012
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
PMCID
3521611
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
PubMed ID
23217703
1 reference
stated in
Europe PubMed Central
PMCID
3521611
retrieved
14 August 2017
ResearchGate publication ID
233875823
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