(Q27618496)

1

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T Zor

2

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D Vogt

3

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W Kabsch

4

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Z Selinger

5

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A Wittinghofer

6

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K Scheffzek

Proceedings of the National Academy of Sciences of the United States of America

7

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language of work or name

English

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publication date

8 June 1999

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published in

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volume

96

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page(s)

7065-70

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issue

12

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cites work

The Ras-RasGAP complex: structural basis for GTPase activation and its loss in oncogenic Ras mutants

1 reference

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The role of the metal ion in the p21ras catalysed GTP-hydrolysis: Mn2+ versus Mg2+

20 March 2017

1 reference

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Three-dimensional structures and properties of a transforming and a nontransforming glycine-12 mutant of p21H-ras

20 March 2017

1 reference

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X-ray crystal structure analysis of the catalytic domain of the oncogene product p21H-ras complexed with caged GTP and mant dGppNHp

20 March 2017

1 reference

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Analysis of RAS oncogene mutations in human lymphoid malignancies

20 March 2017

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A cytoplasmic protein stimulates normal N-ras p21 GTPase, but does not affect oncogenic mutants

20 March 2017

1 reference

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Three-dimensional structures of H-ras p21 mutants: molecular basis for their inability to function as signal switch molecules

20 March 2017

1 reference

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Refined crystal structure of the triphosphate conformation of H-ras p21 at 1.35 A resolution: implications for the mechanism of GTP hydrolysis

20 March 2017

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

20 March 2017

1 reference

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The GTPase superfamily: conserved structure and molecular mechanism

20 March 2017

1 reference

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Lessons from hereditary colorectal cancer

20 March 2017

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Proteins regulating Ras and its relatives

20 March 2017

1 reference

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The GTPase superfamily: a conserved switch for diverse cell functions

20 March 2017

1 reference

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Confirmation of the arginine-finger hypothesis for the GAP-stimulated GTP-hydrolysis reaction of Ras

20 March 2017

1 reference

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ras oncogenes in human cancer: a review

20 March 2017

1 reference

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Mutant ras epitopes as targets for cancer vaccines

7 April 2017

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Tumor cell instability, diversification, and progression to the metastatic phenotype: from oncogene to oncofetal expression

29 September 2017

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Amino-acid substitutions at codon 13 of the N-ras oncogene in human acute myeloid leukaemia

29 September 2017

1 reference

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Mutational and kinetic analyses of the GTPase-activating protein (GAP)-p21 interaction: the C-terminal domain of GAP is not sufficient for full activity

29 September 2017

1 reference

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X-ray crystal structures of transforming p21 ras mutants suggest a transition-state stabilization mechanism for GTP hydrolysis

29 September 2017

1 reference

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The interaction of Ras with GTPase-activating proteins

29 September 2017

1 reference

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Linear free energy relationships in the intrinsic and GTPase activating protein-stimulated guanosine 5'-triphosphate hydrolysis of p21ras.

2 June 2018

1 reference

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Biochemical and biological consequences of changing the specificity of p21ras from guanosine to xanthosine nucleotides.

2 June 2018

1 reference

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Kinetics of interaction between normal and proline 12 Ras and the GTPase-activating proteins, p120-GAP and neurofibromin. The significance of the intrinsic GTPase rate in determining the transforming ability of ras.

2 June 2018

1 reference

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Biological properties of human c-Ha-ras1 genes mutated at codon 12.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=22057

Biological and biochemical properties of human rasH genes mutated at codon 61.

2 June 2018

1 reference

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Expression of p21 proteins in Escherichia coli and stereochemistry of the nucleotide-binding site

2 June 2018

1 reference

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Substrate-assisted catalysis as a mechanism for GTP hydrolysis of p21ras and other GTP-binding proteins.

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.12.7065

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.12.7065

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.12.7065

Crystallization and preliminary X-ray analysis of the human c-H-ras-oncogene product p21 complexed with GTP analogues

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.12.7065

Time-resolved X-ray crystallographic study of the conformational change in Ha-Ras p21 protein on GTP hydrolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.96.12.7065

GTP analogue hydrolysis by the Gs protein: implication for the role of catalytic glutamine in the GTPase reaction

21 January 2018

1 reference

12 December 2020

Kinetics of interaction of nucleotides with nucleotide-free H-ras p21

1 reference

12 December 2020

Substrate and Product Structural Requirements for Binding of Nucleotides to H-ras p21: The Mechanism of Discrimination between Guanosine and Adenosine Nucleotides

1 reference

12 December 2020

Formation of a Transition-State Analog of the Ras GTPase Reaction by Ras GDP, Tetrafluoroaluminate, and GTPase-Activating Proteins

1 reference

12 December 2020

Rescue of a mutant G-protein by substrate-assisted catalysis

1 reference

12 December 2020