(Q27618604)

1

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L Jankova

2

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M Coles

3

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D Jardine

4

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J S Whittaker

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A R Gould

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A Meister

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G C King

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B C Mabbutt

Human alpha 1-proteinase inhibitor. Crystal structure analysis of two crystal modifications, molecular model and preliminary analysis of the implications for function

9

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language of work or name

1 reference

15 January 1999

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published in

Structure

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volume

7

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issue

1

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page(s)

43-54

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cites work

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Crystal structure of ovalbumin as a model for the reactive centre of serpins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Crystal structure of an uncleaved serpin reveals the conformation of an inhibitory reactive loop

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Crystal structure of uncleaved ovalbumin at 1.95 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Crystal structure of cleaved equine leucocyte elastase inhibitor determined at 1.95 A resolution

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

The ovalbumin family of serpin proteins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Inhibitory conformation of the reactive loop of alpha 1-antitrypsin

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Protein inhibitors of proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Natural protein proteinase inhibitors and their interaction with proteinases

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

A 1H NMR probe for mobility in the reactive center loops of serpins: spin-echo studies of native and modified forms of ovalbumin and alpha 1-proteinase inhibitor

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Conformation of the reactive site loop of alpha 1-proteinase inhibitor probed by limited proteolysis

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Probing serpin reactive-loop conformations by proteolytic cleavage

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Implications of the three-dimensional structure of alpha 1-antitrypsin for structure and function of serpins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Amino acid substitution Glu→Lys in α1-antitrypsin PiZ

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

What do dysfunctional serpins tell us about molecular mobility and disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

The intact and cleaved human antithrombin III complex as a model for serpin-proteinase interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

An analysis of side chain interactions and pair correlations within antiparallel beta-sheets: the differences between backbone hydrogen-bonded and non-hydrogen-bonded residue pairs.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Guidelines for protein design: the energetics of beta sheet side chain interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Biological implications of a 3 A structure of dimeric antithrombin

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Inhibitory mechanism of serpins. Mobility of the C-terminal region of the reactive-site loop

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

The inhibition mechanism of serpins. Evidence that the mobile reactive center loop is cleaved in the native protease-inhibitor complex.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Serpin-protease complexes are trapped as stable acyl-enzyme intermediates

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Role of the catalytic serine in the interactions of serine proteinases with protein inhibitors of the serpin family. Contribution of a covalent interaction to the binding energy of serpin-proteinase complexes.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Modeling of serpin-protease complexes: antithrombin-thrombin, alpha 1-antitrypsin (358Met-->Arg)-thrombin, alpha 1-antitrypsin (358Met-->Arg)-trypsin, and antitrypsin-elastase

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

The contribution of the conserved hinge region residues of alpha1-antitrypsin to its reaction with elastase

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Inhibitory activity and conformational transition of alpha1-proteinase inhibitor variants

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Expression of alpha 1-proteinase inhibitor in Escherichia coli: effects of single amino acid substitutions in the active site loop on aggregate formation.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Structural transition of alpha 1-antitrypsin by a peptide sequentially similar to beta-strand s4A.

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Evidence for the extent of insertion of the active site loop of intact alpha 1 proteinase inhibitor in beta-sheet A

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Immunological Detection of Conformational Neoepitopes Associated with the Serpin Activity of Plasminogen Activator Inhibitor Type-2

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Interfering with the inhibitory mechanism of serpins: crystal structure of a complex formed between cleaved plasminogen activator inhibitor type 1 and a reactive-centre loop peptide

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Structural insights into serpin-protease complexes reveal the inhibitory mechanism of serpins

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Major proteinase movement upon stable serpin-proteinase complex formation

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

The structural puzzle of how serpin serine proteinase inhibitors work

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Structural basis for serpin inhibitor activity

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Distortion of the active site of chymotrypsin complexed with a serpin

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

The CCP4 suite: programs for protein crystallography

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Refinement of macromolecular structures by the maximum-likelihood method

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Database of homology-derived protein structures and the structural meaning of sequence alignment

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

Selection of representative protein data sets

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021

SETOR: hardware-lighted three-dimensional solid model representations of macromolecules

1 reference

https://api.crossref.org/works/10.1016%2FS0969-2126%2899%2980008-2

7 January 2021