(Q27619526)

1

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A Lang

2

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A Karcher

3

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K Sichler

4

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E Kopetzki

5

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R Huber

7

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W Bode

8

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R A Engh

The coagulation cascade: initiation, maintenance, and regulation

9

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publication date

15 August 1999

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published in

Structure

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volume

7

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issue

8

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page(s)

989-96

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cites work

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The molecular basis of blood coagulation

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Mapping the active sites of bovine thrombin, factor IXa, factor Xa, factor XIa, factor XIIa, plasma kallikrein, and trypsin with amino acid and peptide thioesters: development of new sensitive substrates

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7 January 2021

Reactivity of bovine blood coagulation factor IXa beta, factor Xa beta, and factor XIa toward fluorogenic peptides containing the activation site sequences of bovine factor IX and factor X.

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7 January 2021

Active-site mapping of bovine and human blood coagulation serine proteases using synthetic peptide 4-nitroanilide and thio ester substrates

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7 January 2021

A comparison of human prothrombin, factor IX (Christmas factor), factor X (Stuart factor), and protein S

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7 January 2021

Mechanism of activation of bovine factor X (Stuart factor) by intrinsic and extrinsic pathways

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Factor Xa-factor Va complex assembles in two dimensions with unexpectedly high affinity: an experimental and theoretical approach

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28 Assay of coagulation proteases using peptide chromogenic and fluorogenic substrates

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Dramatic enhancement of the catalytic activity of coagulation factor IXa by alcohols

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X-ray structure of clotting factor IXa: active site and module structure related to Xase activity and hemophilia B

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7 January 2021

Structure of human des(1-45) factor Xa at 2.2 A resolution

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X-ray structure of active site-inhibited clotting factor Xa. Implications for drug design and substrate recognition

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7 January 2021

Converting blood coagulation factor IXa into factor Xa: dramatic increase in amidolytic activity identifies important active site determinants

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7 January 2021

Refined 2 A X-ray crystal structure of porcine pancreatic kallikrein A, a specific trypsin-like serine proteinase. Crystallization, structure determination, crystallographic refinement, structure and its comparison with bovine trypsin

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7 January 2021

Refined 2.5 A X-ray crystal structure of the complex formed by porcine kallikrein A and the bovine pancreatic trypsin inhibitor. Crystallization, Patterson search, structure determination, refinement, structure and comparison with its [...]

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7 January 2021

The 2.3 A crystal structure of the catalytic domain of recombinant two-chain human tissue-type plasminogen activator

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7 January 2021

Lysine 156 promotes the anomalous proenzyme activity of tPA: X-ray crystal structure of single-chain human tPA.

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Blood coagulation factor IX residues Glu78 and Arg94 provide a link between both epidermal growth factor-like domains that is crucial in the interaction with factor VIII light chain

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Antibody-probed conformational transitions in the protease domain of human factor IX upon calcium binding and zymogen activation: putative high-affinity Ca(2+)-binding site in the protease domain

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7 January 2021

Interaction of factor IXa with factor VIIIa. Effects of protease domain Ca2+ binding site, proteolysis in the autolysis loop, phospholipid, and factor X

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7 January 2021

Comparative modeling methods: application to the family of the mammalian serine proteases

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7 January 2021

Role of residue 99 at the S2 subsite of factor Xa and activated protein C in enzyme specificity

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7 January 2021

PROCHECK: a program to check the stereochemical quality of protein structures

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7 January 2021

New enzyme lineages by subdomain shuffling

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7 January 2021

The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor

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The ternary microplasmin-staphylokinase-microplasmin complex is a proteinase-cofactor-substrate complex in action

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7 January 2021

Crystal structure of the catalytic domain of human plasmin complexed with streptokinase

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7 January 2021

The CCP4 suite: programs for protein crystallography

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7 January 2021

AMoRe: an automated package for molecular replacement

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7 January 2021