(Q27636942)

5

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author name string

Miryam Asuncion

1

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John N Barlow

3

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David Gani

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

8 March 2002

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published in

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volume

277

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issue

10

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page(s)

8306-11

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cites work

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21 January 2018

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A functionally diverse enzyme superfamily that abstracts the alpha protons of carboxylic acids

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Cloning, sequencing, and expression in Escherichia coli of the Clostridium tetanomorphum gene encoding beta-methylaspartase and characterization of the recombinant protein

21 January 2018

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Crystal structure of histidine ammonia-lyase revealing a novel polypeptide modification as the catalytic electrophile

21 January 2018

1 reference

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Insights into enzyme evolution revealed by the structure of methylaspartate ammonia lyase

21 January 2018

1 reference

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Overexpression, purification, crystallization and data collection of 3-methylaspartase from Clostridium tetanomorphum

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Preparation of selenomethionyl proteins for phase determination

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The use of SnB to determine an anomalous scattering substructure

21 January 2018

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Structure determination of selenomethionyl S-adenosylhomocysteine hydrolase using data at a single wavelength

21 January 2018

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The CCP4 suite: programs for protein crystallography

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Automated protein model building combined with iterative structure refinement

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Improved methods for building protein models in electron density maps and the location of errors in these models

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Refinement of macromolecular structures by the maximum-likelihood method

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Basic local alignment search tool

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Protein structure comparison by alignment of distance matrices

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A carboxylate oxygen of the substrate bridges the magnesium ions at the active site of enolase: structure of the yeast enzyme complexed with the equilibrium mixture of 2-phosphoglycerate and phosphoenolpyruvate at 1.8 A resolution

21 January 2018

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Evolution of an enzyme active site: the structure of a new crystal form of muconate lactonizing enzyme compared with mandelate racemase and enolase

21 January 2018

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Evolution of enzymatic activities in the enolase superfamily: identification of the general acid catalyst in the active site of D-glucarate dehydratase from Escherichia coli

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Evolution of enzymatic activity in the enolase superfamily: structure of o-succinylbenzoate synthase from Escherichia coli in complex with Mg2+ and o-succinylbenzoate

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Role of metal ions in catalysis by enolase: an ordered kinetic mechanism for a single substrate enzyme

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Purification and characterization of beta-methylaspartase from Fusobacterium varium

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Mechanism of C-3 hydrogen exchange and the elimination of ammonia in the 3-methylaspartate ammonia-lyase reaction

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Mechanistically diverse enzyme superfamilies: the importance of chemistry in the evolution of catalysis

21 January 2018

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Mechanism of 3-methylaspartase probed using deuterium and solvent isotope effects and active-site directed reagents: identification of an essential cysteine residue

21 January 2018

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The 3-methylaspartase reaction probed using 2H- and 15N-isotope effects for three substrates: a flip from a concerted to a carbocationic amino-enzyme elimination mechanism upon changing the C-3 stereochemistry in the substrate from R to S

21 January 2018

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