(Q27638009)

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Structural insights into group II intron catalysis and branch-site selection

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title

Structural insights into group II intron catalysis and branch-site selection (English)

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author

Jennifer Doudna

series ordinal

2

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author name string

Lan Zhang

series ordinal

1

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language of work or name

English

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publication date

15 March 2002

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published in

Science

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volume

295

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issue

5562

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page(s)

2084-8

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cites work

Branch nucleophile selection in pre-mRNA splicing: evidence for the bulged duplex model

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Building a kinetic framework for group II intron ribozyme activity: quantitation of interdomain binding and reaction rate

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Crystal structure of a group I ribozyme domain: principles of RNA packing

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

A compensatory base change in human U2 snRNA can suppress a branch site mutation

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

A tertiary interaction that links active-site domains to the 5' splice site of a group II intron

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Metal-ion coordination by U6 small nuclear RNA contributes to catalysis in the spliceosome.

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

A general module for RNA crystallization

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Ribozymes: a distinct class of metalloenzymes

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Catalytic site components common to both splicing steps of a group II intron

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Catalytic role of 2'-hydroxyl groups within a group II intron active site

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Metal ion binding sites in a group II intron core

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Photocrosslinking of 4-thio uracil-containing RNAs supports a side-by-side arrangement of domains 5 and 6 of a group II intron

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Determination of macromolecular structures from anomalous diffraction of synchrotron radiation

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

A self-splicing RNA excises an intron lariat

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

2.8 A crystal structure of the malachite green aptamer

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

More than one way to splice an RNA: branching without a bulge and splicing without branching in group II introns.

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

A magnesium ion core at the heart of a ribozyme domain

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Defining functional groups, core structural features and inter-domain tertiary contacts essential for group II intron self-splicing: a NAIM analysis

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Recognition of the TACTAAC box during mRNA splicing in yeast involves base pairing to the U2-like snRNA.

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Mammalian pre-mRNA branch site selection by U2 snRNP involves base pairing.

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9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Catalytically critical nucleotide in domain 5 of a group II intron

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Structure and activities of group II introns

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Differential chemical probing of a group II self-splicing intron identifies bases involved in tertiary interactions and supports an alternative secondary structure model of domain V

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Metal ion catalysis during group II intron self-splicing: parallels with the spliceosome

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Crystal structure of a model branchpoint-U2 snRNA duplex containing bulged adenosines

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Position and orientation of the globular domain of linker histone H5 on the nucleosome.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Frequent use of the same tertiary motif by self-folding RNAs

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Control of branch-site choice by a group II intron

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Two competing pathways for self-splicing by group II introns: a quantitative analysis of in vitro reaction rates and products

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

The architectural organization and mechanistic function of group II intron structural elements

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

The question remains: is the spliceosome a ribozyme?

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Metal ion coordination by the AGC triad in domain 5 contributes to group II intron catalysis

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

Ribozyme catalysis from the major groove of group II intron domain 5.

1 reference

9 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1126/SCIENCE.1069268

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DOI

10.1126/SCIENCE.1069268

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ResearchGate publication ID

11503055

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(Q27638009)

Structural insights into group II intron catalysis and branch-site selection

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