(Q27639192)

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Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues

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Determinants of the inhibition of a Taiwan habu venom metalloproteinase by its endogenous inhibitors revealed by X-ray crystallography and synthetic inhibitor analogues (English)

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X-ray crystallography

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Andrew H.-J. Wang

4

object named as

Andrew H-J Wang

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3

object named as

Tzu-Ping Ko

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author name string

Kai-Fa Huang

1

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Shyh-Horng Chiou

2

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language of work or name

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publication date

June 2002

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269

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12

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3047-56

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Snake venom metalloproteinases: their role in the pathogenesis of local tissue damage

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Sequence of a cDNA clone encoding the zinc metalloproteinase hemorrhagic toxin e from Crotalus atrox: evidence for signal, zymogen, and disintegrin-like structures

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Citrate inhibition of snake venom proteases.

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Isolation from opossum serum of a metalloproteinase inhibitor homologous to human .alpha.1B-glycoprotein

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Structural and functional analyses of DM43, a snake venom metalloproteinase inhibitor from Didelphis marsupialis serum

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BJ46a, a snake venom metalloproteinase inhibitor. Isolation, characterization, cloning and insights into its mechanism of action.

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The metzincins--topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a superfamily of zinc-peptidases

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Structural features of a superfamily of zinc-endopeptidases: the metzincins

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ADAMs in fertilization and development

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KUZ, a conserved metalloprotease-disintegrin protein with two roles in Drosophila neurogenesis

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Purification and cloning of aggrecanase-1: a member of the ADAMTS family of proteins

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Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme

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A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells

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Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha

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Processing of pro-tumor necrosis factor-alpha by venom metalloproteinases: a hypothesis explaining local tissue damage following snake bite

1 reference

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2 angstrom X-ray structure of adamalysin II complexed with a peptide phosphonate inhibitor adopting a retro-binding mode

1 reference

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Structures of adamalysin II with peptidic inhibitors. Implications for the design of tumor necrosis factor alpha convertase inhibitors

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Design, synthesis, and structure-activity relationships of macrocyclic hydroxamic acids that inhibit tumor necrosis factor alpha release in vitro and in vivo.

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Design and therapeutic application of matrix metalloproteinase inhibitors

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The determination of enzyme inhibitor constants

1 reference

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Processing of X-ray diffraction data collected in oscillation mode

1 reference

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Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

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PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

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X-ray structures of human neutrophil collagenase complexed with peptide hydroxamate and peptide thiol inhibitors. Implications for substrate binding and rational drug design

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Structural interaction of natural and synthetic inhibitors with the venom metalloproteinase, atrolysin C (form d)

1 reference

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The 1.8-A crystal structure of a matrix metalloproteinase 8-barbiturate inhibitor complex reveals a previously unobserved mechanism for collagenase substrate recognition

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Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding

1 reference

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The interpretation of protein structures: Total volume, group volume distributions and packing density

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Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro.

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Accurate bond and angle parameters for X-ray protein structure refinement

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Hemorrhagic Toxins from Snake Venoms

1 reference

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Activation of snake venom metalloproteinases by a cysteine switch-like mechanism

1 reference

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The isolation and amino acid sequences of new pyroglutamylpeptides from snake venoms

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Inhibition of metalloproteinases in Bothrops asper venom by endogenous peptides

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Primary structure of the antihemorrhagic factor in serum of the Japanese Habu: a snake venom metalloproteinase inhibitor with a double-headed cystatin domain

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Isolation and characterization of a novel proteinase inhibitor from the snake serum of Taiwan habu (Trimeresurus mucrosquamatus)

1 reference

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The metzincin-superfamily of zinc-peptidases.

1 reference

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Inhibition of adamalysin II and MMPs by phosphonate analogues of snake venom peptides

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New alpha-substituted succinate-based hydroxamic acids as TNFalpha convertase inhibitors

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Characterization of three endogenous peptide inhibitors for multiple metalloproteinases with fibrinogenolytic activity from the venom of Taiwan habu (Trimeresurus mucrosquamatus)

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Identifiers

10.1046/J.1432-1033.2002.02982.X

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