(Q27641891)

2

0 references

Hideaki Shimizu

3

0 references

Clinton Nishida

4

0 references

Hiroshi Ogura

5

0 references

Paul R Ortiz de Montellano

6

0 references

Thomas L Poulos

Journal of Biological Chemistry

7

0 references

language of work or name

English

0 references

publication date

7 November 2003

0 references

published in

0 references

volume

278

0 references

issue

45

0 references

page(s)

44886-93

0 references

cites work

Plant antitumor agents. VI. The isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Discodermolide, a cytotoxic marine agent that stabilizes microtubules more potently than taxol

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Activities of the microtubule-stabilizing agents epothilones A and B with purified tubulin and in cells resistant to paclitaxel (Taxol(R)).

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Cloning and heterologous expression of the epothilone gene cluster.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Characterization of Saccharopolyspora erythraea cytochrome P-450 genes and enzymes, including 6-deoxyerythronolide B hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Automated MAD and MIR structure solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Maximum-likelihood density modification

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Efficient anisotropic refinement of macromolecular structures using FFT

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Detection, delineation, measurement and display of cavities in macromolecular structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Raster3D Version 2.0. A program for photorealistic molecular graphics

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Comparison of the dynamics of substrate access channels in three cytochrome P450s reveals different opening mechanisms and a novel functional role for a buried arginine

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Uncoupling of the cytochrome P-450cam monooxygenase reaction by a single mutation, threonine-252 to alanine or valine: possible role of the hydroxy amino acid in oxygen activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Structure of cytochrome P450eryF involved in erythromycin biosynthesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Spin-state changes in cytochrome P-450cam on binding of specific substrates

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Coupling of spin, substrate, and redox equilibriums in cytochrome P450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Substrate recognition and molecular mechanism of fatty acid hydroxylation by cytochrome P450 from Bacillus subtilis. Crystallographic, spectroscopic, and mutational studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Crystal structure of substrate-free Pseudomonas putida cytochrome P-450

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

The structure of the cytochrome p450BM-3 haem domain complexed with the fatty acid substrate, palmitoleic acid

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Crystal structure of hemoprotein domain of P450BM-3, a prototype for microsomal P450's

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Mammalian microsomal cytochrome P450 monooxygenase: structural adaptations for membrane binding and functional diversity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Structure of a substrate complex of mammalian cytochrome P450 2C5 at 2.3 A resolution: evidence for multiple substrate binding modes

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Crystal structure of a thermophilic cytochrome P450 from the archaeon Sulfolobus solfataricus

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Refined structure of alpha beta-tubulin at 3.5 A resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Paclitaxel-resistant human ovarian cancer cells have mutant beta-tubulins that exhibit impaired paclitaxel-driven polymerization

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

A common pharmacophore for epothilone and taxanes: molecular basis for drug resistance conferred by tubulin mutations in human cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

The coral-derived natural products eleutherobin and sarcodictyins A and B: effects on the assembly of purified tubulin with and without microtubule-associated proteins and binding at the polymer taxoid site.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Desoxyepothilone B: an efficacious microtubule-targeted antitumor agent with a promising in vivo profile relative to epothilone B.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

PROCHECK: a program to check the stereochemical quality of protein structures

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Epothilone A and B—Novel 16-Membered Macrolides with Cytotoxic Activity: Isolation, Crystal Structure, and Conformation in Solution

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Eleutherobin, a New Cytotoxin that Mimics Paclitaxel (Taxol) by Stabilizing Microtubules

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Sarcodictyin A and Sarcodictyin B, Novel Diterpenoidic Alcohols Esterified by (E)-N(1)-Methylurocanic Acid. Isolation from the Mediterranean StoloniferSarcodictyon roseum

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

Chemical Biology of Epothilones

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M308115200

21 January 2018

Identifiers

DOI

10.1074/JBC.M308115200

1 reference

Consolidated OpenCitations Corpus – April 2017

4469426

4469426

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

1 reference