(Q27642730)

English

Crystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activity

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scholarly article

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Crystal structure of human tryptophanyl-tRNA synthetase catalytic fragment: insights into substrate recognition, tRNA binding, and angiogenesis activity (English)

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crystal structure

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1 reference

based on heuristic

inferred from title

8

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author name string

Yadong Yu

1

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Yunqing Liu

2

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Ning Shen

3

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Xiang Xu

4

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Feng Xu

5

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Jie Jia

6

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Youxin Jin

7

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Jianping Ding

9

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language of work or name

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publication date

27 February 2004

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Journal of Biological Chemistry

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279

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9

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8378-88

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Aminoacyl tRNA synthetases: general scheme of structure-function relationships in the polypeptides and recognition of transfer RNAs

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Partition of tRNA synthetases into two classes based on mutually exclusive sets of sequence motifs

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Cognition, mechanism, and evolutionary relationships in aminoacyl-tRNA synthetases

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Presence and abundance of CENP-B box sequences in great ape subsets of primate-specific alpha-satellite DNA.

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Sequence similarities among the family of aminoacyl-tRNA synthetases.

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Intron positions delineate the evolutionary path of a pervasively appended peptide in five human aminoacyl-tRNA synthetases

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Transcriptional regulation of the interferon-gamma-inducible tryptophanyl-tRNA synthetase includes alternative splicing

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Alternative processing of the tryptophanyl-tRNA synthetase mRNA from interferon-treated human cells

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Species-specific differences in the operational RNA code for aminoacylation of tRNA(Trp)

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A human aminoacyl-tRNA synthetase as a regulator of angiogenesis

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A fragment of human TrpRS as a potent antagonist of ocular angiogenesis

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Human tyrosyl-tRNA synthetase shares amino acid sequence homology with a putative cytokine

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Two distinct cytokines released from a human aminoacyl-tRNA synthetase

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Crystal structure of a human aminoacyl-tRNA synthetase cytokine

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Tryptophanyl-tRNA synthetase crystal structure reveals an unexpected homology to tyrosyl-tRNA synthetase.

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Interconversion of ATP binding and conformational free energies by tryptophanyl-tRNA synthetase: structures of ATP bound to open and closed, pre-transition-state conformations

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High-level expression and single-step purification of human tryptophanyl-tRNA synthetase

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Processing of X-ray diffraction data collected in oscillation mode

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Solvent content of protein crystals

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Automated MAD and MIR structure solution

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Maximum-likelihood density modification using pattern recognition of structural motifs

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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Incorporation of prior phase information strengthens maximum-likelihood structure refinement

1 reference

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Evidence for dispensable sequences inserted into a nucleotide fold.

1 reference

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Sequence determination and modeling of structural motifs for the smallest monomeric aminoacyl-tRNA synthetase

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A dispensable peptide from Acidithiobacillus ferrooxidans tryptophanyl-tRNA synthetase affects tRNA binding.

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Structure of E. coli glutaminyl-tRNA synthetase complexed with tRNA(Gln) and ATP at 2.8 A resolution

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Genetic code in evolution: switching species-specific aminoacylation with a peptide transplant

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A cytochrome c mutant with high electron transfer and antioxidant activities but devoid of apoptogenic effect

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Enzyme structure with two catalytic sites for double-sieve selection of substrate

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Insights into editing from an ile-tRNA synthetase structure with tRNAile and mupirocin

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A conserved threonine within Escherichia coli leucyl-tRNA synthetase prevents hydrolytic editing of leucyl-tRNALeu

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Reconstruction by site-directed mutagenesis of the transition state for the activation of tyrosine by the tyrosyl-tRNA synthetase: a mobile loop envelopes the transition state in an induced-fit mechanism

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Ancient adaptation of the active site of tryptophanyl-tRNA synthetase for tryptophan binding

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Class I tyrosyl-tRNA synthetase has a class II mode of cognate tRNA recognition

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Identity determinants ofE.colitryptophan tRNA

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Induction of angiogenesis by a fragment of human tyrosyl-tRNA synthetase

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Bone marrow-derived stem cells target retinal astrocytes and can promote or inhibit retinal angiogenesis

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Cytokines: coordinators of immune and inflammatory responses

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Molecular mechanisms of cytokine receptor activation

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Structure, binding, and antagonists in the IL-4/IL-13 receptor system.

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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Dictionary of protein secondary structure: pattern recognition of hydrogen-bonded and geometrical features

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ESPript: analysis of multiple sequence alignments in PostScript

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Specific sequence homology and three-dimensional structure of an aminoacyl transfer RNA synthetase

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Identifiers

10.1074/JBC.M311284200

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