Home
Random
Nearby
Log in
Settings
Donate
About Wikidata
Disclaimers
Search
(Q34991803)
Watch
English
Structure, binding, and antagonists in the IL-4/IL-13 receptor system.
scientific article
In more languages
edit
Statements
instance of
scholarly article
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
review article
1 reference
stated in
Europe PubMed Central
title
Structure, binding, and antagonists in the IL-4/IL-13 receptor system
(English)
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
author
Albert Duschl
series ordinal
4
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
author name string
Thomas D Mueller
series ordinal
1
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Jin-Li Zhang
series ordinal
2
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Walter Sebald
series ordinal
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
language of work or name
English
0 references
publication date
1 November 2002
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
number of pages
14
1 reference
based on heuristic
inferred from page(s)
published in
Biochimica et Biophysica Acta
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
volume
1592
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
issue
3
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
page(s)
237-250
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
cites work
Pollution and the immune response: atopic diseases--are we too dirty or too clean?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Reply to rook
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The causes of the increasing prevalence of allergy: is atopy a microbial deprivation disorder?
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular basis of allergic diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The TH1/TH2 paradigm in allergy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The IL-4 receptor: signaling mechanisms and biologic functions
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular regulation of human IgE synthesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular mechanisms of immunoglobulin E regulation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
T-cell subsets (Th1 versus Th2).
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Murine eotaxin-2: a constitutive eosinophil chemokine induced by allergen challenge and IL-4 overexpression
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
STAT6 mediates eotaxin-1 expression in IL-4 or TNF-alpha-induced fibroblasts
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-4 enhances proliferation and mediator release in mature human mast cells
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Basophilic differentiation of the human leukemia cell line KU812 upon treatment with interleukin-4.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The role of IL-13 and its receptor in allergy and inflammatory responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-13 in allergy: home at last
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-13: central mediator of allergic asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Pulmonary expression of interleukin-13 causes inflammation, mucus hypersecretion, subepithelial fibrosis, physiologic abnormalities, and eotaxin production
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Genetic variants of IL-13 signalling and human asthma and atopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-13 overexpression predisposes to anaphylaxis following antigen sensitization
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Requirement for IL-13 independently of IL-4 in experimental asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Therapeutic effect of IL-13 immunoneutralization during chronic experimental fungal asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-13 is a new human lymphokine regulating inflammatory and immune responses
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interleukin-2 receptor gamma chain: its role in the multiple cytokine receptor complexes and T cell development in XSCID
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cutting edge: the common gamma-chain is an indispensable subunit of the IL-21 receptor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor gamma chain: a functional component of the interleukin-4 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor gamma chain mutation results in X-linked severe combined immunodeficiency in humans
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of a specific interleukin (IL)-13 binding protein structurally related to the IL-5 receptor alpha chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Differences between IL-4R alpha-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-13, IL-4Ralpha, and Stat6 are required for the expulsion of the gastrointestinal nematode parasite Nippostrongylus brasiliensis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional aspects of the interaction between growth hormone and its receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Binding in the growth hormone receptor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Selective development of T helper (Th)2 cells induced by continuous administration of low dose soluble proteins to normal and beta(2)-microglobulin-deficient BALB/c mice
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Prevention of the development of immediate hypersensitivity and airway hyperresponsiveness following in vivo treatment with soluble IL-4 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Design of human interleukin-4 antagonists inhibiting interleukin-4-dependent and interleukin-13-dependent responses in T-cells and B-cells with high efficiency
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homodimerization of interleukin-4 receptor alpha chain can induce intracellular signaling
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-4-specific signal transduction events are driven by homotypic interactions of the interleukin-4 receptor alpha subunit.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
In vivo biological effects of recombinant soluble interleukin-4 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Soluble interleukin-4 receptor (sIL-4R) in allergic diseases
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Enhancement of human IL-4 activity by soluble IL-4 receptors in vitro
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-4 receptor in moderate atopic asthma. A phase I/II randomized, placebo-controlled trial.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficacy of soluble IL-4 receptor for the treatment of adults with asthma
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Two distinct functional sites of human interleukin 4 are identified by variants impaired in either receptor binding or receptor activation.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antagonistic mutant of interleukin-4 fails to recruit gamma c into the receptor complex. Characterization by specific crosslinking
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A murine interleukin-4 antagonistic mutant protein completely inhibits interleukin-4-induced cell proliferation, differentiation, and signal transduction
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A murine IL-4 receptor antagonist that inhibits IL-4- and IL-13-induced responses prevents antigen-induced airway eosinophilia and airway hyperresponsiveness
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The Interleukin-4-Receptor: From Recognition Mechanism to Pharmacological Target Structure
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural comparisons among the short-chain helical cytokines
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three-dimensional solution structure of human interleukin-4 by multidimensional heteronuclear magnetic resonance spectroscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human interleukin 4. The solution structure of a four-helix bundle protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of human recombinant interleukin-4 at 2.25 A resolution
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Aspects of receptor binding and signalling of interleukin-4 investigated by site-directed mutagenesis and NMR spectroscopy
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human interleukin-4 and variant R88Q: phasing X-ray diffraction data by molecular replacement using X-ray and nuclear magnetic resonance models
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Global and local determinants for the kinetics of interleukin-4/interleukin-4 receptor alpha chain interaction. A biosensor study employing recombinant interleukin-4-binding protein
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The interleukin-4 site-2 epitope determining binding of the common receptor gamma chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of the interleukin-4/receptor alpha chain complex reveals a mosaic binding interface
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Receptor binding properties of four-helix-bundle growth factors deduced from electrostatic analysis.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural design and molecular evolution of a cytokine receptor superfamily
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of an extracellular gp130 cytokine receptor signaling complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystal structure of a cytokine-binding region of gp130.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Efficiency of signalling through cytokine receptors depends critically on receptor orientation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional mimicry of a protein hormone by a peptide agonist: the EPO receptor complex at 2.8 A
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Crystallographic evidence for preformed dimers of erythropoietin receptor before ligand activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The signal transducer gp130: Solution structure of the carboxy-terminal domain of the cytokine receptor homology region
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Ligand binding characteristics of the carboxyl-terminal domain of the cytokine receptor homologous region of the granulocyte colony-stimulating factor receptor.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
The high-affinity interaction of human IL-4 and the receptor alpha chain is constituted by two independent binding clusters
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
High-resolution epitope mapping of hGH-receptor interactions by alanine-scanning mutagenesis
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Comparison of a structural and a functional epitope
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Human growth hormone and extracellular domain of its receptor: crystal structure of the complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structural and functional epitopes in the growth hormone receptor complex.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A mixed-charge pair in human interleukin 4 dominates high-affinity interaction with the receptor alpha chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Structure of interleukin 4 mutant E9A suggests polar steering in receptor-complex formation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Interleukin-2 receptor gamma chain: a functional component of the interleukin-7 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
cDNA cloning and characterization of the human interleukin 13 receptor alpha chain
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning and characterization of a binding subunit of the interleukin 13 receptor that is also a component of the interleukin 4 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A novel 4-kb interleukin-13 receptor alpha mRNA expressed in human B, T, and endothelial cells encoding an alternate type-II interleukin-4/interleukin-13 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Cloning of the human IL-13R alpha1 chain and reconstitution with the IL4R alpha of a functional IL-4/IL-13 receptor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Functional epitope of common gamma chain for interleukin-4 binding
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL-4 receptor complexes containing or lacking the gamma C chain are inhibited by an overlapping set of antagonistic IL-4 mutant proteins.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An immune cell-selective interleukin 4 agonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Site-directed mutagenesis reveals the importance of disulfide bridges and aromatic residues for structure and proliferative activity of human Interleukin-4
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Antagonist design through forced electrostatic mismatch
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular modeling-guided mutagenesis of the extracellular part of gp130 leads to the identification of contact sites in the interleukin-6 (IL-6).IL-6 receptor.gp130 complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three residues in the common beta chain of the human GM-CSF, IL-3 and IL-5 receptors are essential for GM-CSF and IL-5 but not IL-3 high affinity binding and interact with Glu21 of GM-CSF
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Molecular determinants of the granulocyte-macrophage colony-stimulating factor receptor complex assembly
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Homology modeling study of the human interleukin-7 receptor complex
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Three loops of the common gamma chain ectodomain required for the binding of interleukin-2 and interleukin-7
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
IL2RGbase: a database of gamma c-chain defects causing human X-SCID
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Both interleukin 4 and interleukin 13 induce tyrosine phosphorylation of the 140-kDa subunit of the interleukin 4 receptor
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An interleukin 4 (IL-4) mutant protein inhibits both IL-4 or IL-13-induced human immunoglobulin G4 (IgG4) and IgE synthesis and B cell proliferation: support for a common component shared by IL-4 and IL-13 receptors
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Inhibition of human IgE synthesis in vitro and in SCID-hu mice by an interleukin-4 receptor antagonist
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A single tyrosine residue in the membrane-proximal domain of the granulocyte-macrophage colony-stimulating factor, interleukin (IL)-3, and IL-5 receptor common beta-chain is necessary and sufficient for high affinity binding and signaling by all thr
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Affinity maturation of human growth hormone by monovalent phage display
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Monovalent phage display of human interleukin (hIL)-6: selection of superbinder variants from a complex molecular repertoire in the hIL-6 D-helix.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Engineering human interleukin-6 to obtain variants with strongly enhanced bioactivity.
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
A T-cell-selective interleukin 2 mutein exhibits potent antitumor activity and is well tolerated in vivo
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Q57902397
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
An antagonist peptide-EPO receptor complex suggests that receptor dimerization is not sufficient for activation
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Shared and unique determinants of the erythropoietin (EPO) receptor are important for binding EPO and EPO mimetic peptide
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Raster3D: photorealistic molecular graphics
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons
1 reference
stated in
Crossref
reference URL
https://api.crossref.org/works/10.1016%2FS0167-4889%2802%2900318-X
retrieved
7 January 2021
based on heuristic
inferred from DOI database lookup
Identifiers
DOI
10.1016/S0167-4889(02)00318-X
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
PubMed ID
12421669
1 reference
stated in
Europe PubMed Central
PubMed ID
12421669
reference URL
https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12421669%20AND%20SRC:MED&resulttype=core&format=json
retrieved
14 December 2019
Sitelinks
Wikipedia
(0 entries)
edit
Wikibooks
(0 entries)
edit
Wikinews
(0 entries)
edit
Wikiquote
(0 entries)
edit
Wikisource
(0 entries)
edit
Wikiversity
(0 entries)
edit
Wikivoyage
(0 entries)
edit
Wiktionary
(0 entries)
edit
Multilingual sites
(0 entries)
edit
