(Q27642975)

2

0 references

Dario Alessi

object named as

Dario R Alessi

4

0 references

Christine C Milburn

1

object named as

Christine C Milburn

0 references

author name string

Daan M F van Aalten

Nature Structural & Molecular Biology

5

0 references

publication date

February 2004

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published in

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volume

11

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issue

2

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page(s)

193-200

0 references

cites work

LKB1, a protein kinase regulating cell proliferation and polarity

1 reference

A serine/threonine kinase gene defective in Peutz-Jeghers syndrome

21 January 2018

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Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase

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Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice

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Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

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Role of Lkb1, the causative gene of Peutz-Jegher's syndrome, in embryogenesis and polyposis

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Growth suppression by Lkb1 is mediated by a G(1) cell cycle arrest

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The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death

21 January 2018

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Growth arrest by the LKB1 tumor suppressor: induction of p21(WAF1/CIP1).

21 January 2018

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A role for Drosophila LKB1 in anterior-posterior axis formation and epithelial polarity

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LKB1 (XEEK1) regulates Wnt signalling in vertebrate development

21 January 2018

1 reference

Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1

21 January 2018

1 reference

Activation of the tumour suppressor kinase LKB1 by the STE20-like pseudokinase STRAD

21 January 2018

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MO25alpha/beta interact with STRADalpha/beta enhancing their ability to bind, activate and localize LKB1 in the cytoplasm

21 January 2018

1 reference

Complexes between the LKB1 tumor suppressor, STRAD alpha/beta and MO25 alpha/beta are upstream kinases in the AMP-activated protein kinase cascade

21 January 2018

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LKB1 is the upstream kinase in the AMP-activated protein kinase cascade

21 January 2018

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Automated protein model building combined with iterative structure refinement

21 January 2018

1 reference

Molecular cloning of a novel mRNA sequence expressed in cleavage stage mouse embryos

21 January 2018

1 reference

Molecular characterization of the Drosophila Mo25 gene, which is conserved among Drosophila, mouse, and yeast

21 January 2018

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Calmodulin structure refined at 1.7 A resolution

21 January 2018

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Protein structure comparison by alignment of distance matrices

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Autoinhibition by an internal nuclear localization signal revealed by the crystal structure of mammalian importin alpha

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Structural view of the Ran-Importin beta interaction at 2.3 A resolution

21 January 2018

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Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin alpha

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Structure of Pumilio reveals similarity between RNA and peptide binding motifs

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Crystal structure of a Pumilio homology domain

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Modular recognition of RNA by a human pumilio-homology domain

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Topological characteristics of helical repeat proteins

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Protein repeats: structures, functions, and evolution

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Crystallization and characterization of Pumilo: a novel RNA binding protein.

21 January 2018

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GLFG and FxFG nucleoporins bind to overlapping sites on importin-beta

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Molecular basis for the recognition of a nonclassical nuclear localization signal by importin beta

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Crystallographic analysis of the specific yet versatile recognition of distinct nuclear localization signals by karyopherin alpha

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Crystal structure of a beta-catenin/Tcf complex

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The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

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ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

21 January 2018

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The high resolution crystal structure of recombinant Crithidia fasciculata tryparedoxin-I

21 January 2018

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Processing of X-ray diffraction data collected in oscillation mode

21 January 2018

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Automated MAD and MIR structure solution

21 January 2018

1 reference

Improved methods for building protein models in electron density maps and the location of errors in these models

21 January 2018

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Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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AMoRe: an automated package for molecular replacement

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Refinement of macromolecular structures by the maximum-likelihood method

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Use of TLS parameters to model anisotropic displacements in macromolecular refinement

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Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons

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The armadillo family of structural proteins.

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1 reference