(Q27650089)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344977%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

title

NFkappaB selectivity of estrogen receptor ligands revealed by comparative crystallographic analyses (English)

1 reference

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4 January 2020

0 references

1 reference

3

1 reference

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4 January 2020

Sanjeev Kumar Sharma

5

1 reference

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4 January 2020

Hai-Bing Zhou

9

1 reference

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4 January 2020

Benita Katzenellenbogen

11

object named as

Benita S Katzenellenbogen

1 reference

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4 January 2020

14

Geoffrey L Greene

1 reference

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4 January 2020

author name string

Kendall W Nettles

1

1 reference

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4 January 2020

John B Bruning

2

1 reference

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4 January 2020

Jason Nowak

4

1 reference

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4 January 2020

Johnnie B Hahm

6

1 reference

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4 January 2020

Kristen Kulp

7

1 reference

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4 January 2020

Richard B Hochberg

8

1 reference

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4 January 2020

John A Katzenellenbogen

10

1 reference

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4 January 2020

Younchang Kim

12

1 reference

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4 January 2020

Andrzej Joachmiak

13

1 reference

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4 January 2020

publication date

16 March 2008

1 reference

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4 January 2020

published in

Nature Chemical Biology

1 reference

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4 January 2020

volume

4

1 reference

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4 January 2020

issue

4

1 reference

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4 January 2020

page(s)

241-247

1 reference

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Partial agonists activate PPARgamma using a helix 12 independent mechanism

4 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

CBP Is a dosage-dependent regulator of nuclear factor-kappaB suppression by the estrogen receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Elemental isomerism: a boron-nitrogen surrogate for a carbon-carbon double bond increases the chemical diversity of estrogen receptor ligands

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Structural plasticity in the oestrogen receptor ligand-binding domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Structural insights into the mode of action of a pure antiestrogen

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Structure and specificity of nuclear receptor-coactivator interactions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

A new vector for high-throughput, ligation-independent cloning encoding a tobacco etch virus protease cleavage site

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Structure-guided optimization of estrogen receptor binding affinity and antagonist potency of pyrazolopyrimidines with basic side chains.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Hormone-PAMAM dendrimer conjugates: polymer dynamics and tether structure affect ligand access to receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Identification of ligands with bicyclic scaffolds provides insights into mechanisms of estrogen receptor subtype selectivity.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

PhIP carcinogenicity in breast cancer: computational and experimental evidence for competitive interactions with human estrogen receptor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Synthesis and evaluation of estrogen receptor ligands with bridged oxabicyclic cores containing a diarylethylene motif: estrogen antagonists of unusual structure

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

A fully dissociated compound of plant origin for inflammatory gene repression

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Isocoumarins as estrogen receptor beta selective ligands: Isomers of isoflavone phytoestrogens and their metabolites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Nonpolar and short side chain groups at C-11beta of estradiol result in antiestrogens.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Indazole estrogens: highly selective ligands for the estrogen receptor beta.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Identification of pathway-selective estrogen receptor ligands that inhibit NF-kappaB transcriptional activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Synthesis and activity of substituted 4-(indazol-3-yl)phenols as pathway-selective estrogen receptor ligands useful in the treatment of rheumatoid arthritis.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

The flip side: Identifying small molecule regulators of nuclear receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Mutations of tyrosine 537 in the human estrogen receptor-alpha selectively alter the receptor's affinity for estradiol and the kinetics of the interaction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Ligand-independent activation of the estrogen receptors alpha and beta by mutations of a conserved tyrosine can be abolished by antiestrogens.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Identification of amino acids in the hormone binding domain of the human estrogen receptor important in estrogen binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Function of estrogen receptor tyrosine 537 in hormone binding, DNA binding, and transactivation.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Altered ligand binding properties and enhanced stability of a constitutively active estrogen receptor: evidence that an open pocket conformation is required for ligand interaction.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Constitutively active human estrogen receptors containing amino acid substitutions for tyrosine 537 in the receptor protein.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Bridged bicyclic cores containing a 1,1-diarylethylene motif are high-affinity subtype-selective ligands for the estrogen receptor

19 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Mechanistic aspects of estrogen receptor activation probed with constitutively active estrogen receptors: correlations with DNA and coregulator interactions and receptor conformational changes.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2659626

Ligand-induced stabilization of PPARgamma monitored by NMR spectroscopy: implications for nuclear receptor activation

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18344977

12 December 2020

inferred from PubMed ID database lookup

Mechanistic Aspects of Estrogen Receptor Activation Probed with Constitutively Active Estrogen Receptors: Correlations with DNA and Coregulator Interactions and Receptor Conformational Changes

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.76

7 January 2021

inferred from DOI database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.76

7 January 2021

inferred from DOI database lookup

The CCP4 suite: programs for protein crystallography

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.76

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1038/NCHEMBIO.76

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344977%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

4 January 2020

1025380413

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18344977%20AND%20SRC:MED&resulttype=core&format=json

4 January 2020

PubMed publication ID

18344977

2 references