(Q27651416)

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Structure of theBrachydanio rerioPolo-like kinase 1 (Plk1) catalytic domain in complex with an extended inhibitor targeting the adaptive pocket of the enzyme

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Structure of theBrachydanio rerioPolo-like kinase 1 (Plk1) catalytic domain in complex with an extended inhibitor targeting the adaptive pocket of the enzyme (English)

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structural biology

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condensed matter physics

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Raymond V Fucini

2

object named as

Raymond V Fucini

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Michael J Romanowski

8

object named as

Michael J Romanowski

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3

object named as

Emily J Hanan

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author name string

Robert A Elling

1

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Kenneth J Barr

4

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Jiang Zhu

5

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Kumar Paulvannan

6

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Wenjin Yang

7

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publication date

1 August 2008

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Acta Crystallographica Section F: Structural Biology Communications

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64

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Pt 8

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686-91

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Structures of the wild-type and activated catalytic domains of Brachydanio rerio Polo-like kinase 1 (Plk1): changes in the active-site conformation and interactions with ligands

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20 March 2017

Structure of wild-type Plk-1 kinase domain in complex with a selective DARPin

1 reference

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20 March 2017

Selectivity-determining residues in Plk1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2494981

20 March 2017

Structure of the catalytic domain of human polo-like kinase 1

1 reference

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20 March 2017

Molecular and structural basis of polo-like kinase 1 substrate recognition: Implications in centrosomal localization

1 reference

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20 March 2017

The crystal structure of the human polo-like kinase-1 polo box domain and its phospho-peptide complex

1 reference

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20 March 2017

The molecular basis for phosphodependent substrate targeting and regulation of Plks by the Polo-box domain

1 reference

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20 March 2017

Efficient anisotropic refinement of macromolecular structures using FFT

1 reference

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20 March 2017

SFCHECK: a unified set of procedures for evaluating the quality of macromolecular structure-factor data and their agreement with the atomic model

1 reference

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20 March 2017

Improved methods for building protein models in electron density maps and the location of errors in these models

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20 March 2017

Model preparation in MOLREP and examples of model improvement using X-ray data

1 reference

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29 September 2017

Molecular recognition of protein kinase binding pockets for design of potent and selective kinase inhibitors

1 reference

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29 September 2017

Normal cells, but not cancer cells, survive severe Plk1 depletion

1 reference

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29 September 2017

Getting in and out of mitosis with Polo-like kinase-1.

1 reference

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29 September 2017

Polo-like kinases and oncogenesis

1 reference

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29 September 2017

Mouse Aurora A: expression in Escherichia coli and purification.

1 reference

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27 November 2018

Allosteric inhibition of PTP1B activity by selective modification of a non-active site cysteine residue

1 reference

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27 November 2018

Identifiers

10.1107/S1744309108019623

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release_hynp5af6nrgjxoiaq6bgwny7rq

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