(Q27652631)

22 June 2017

title

The structure of a transcribing T7 RNA polymerase in transition from initiation to elongation (English)

1 reference

22 June 2017

Kimberly J Durniak

1

1 reference

22 June 2017

Scott Bailey

series ordinal

2

1 reference

22 June 2017

Thomas A Steitz

series ordinal

3

1 reference

22 June 2017

language of work or name

English

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publication date

1 October 2008

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22 June 2017

number of pages

5

1 reference

inferred from page(s)

published in

Science

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22 June 2017

volume

322

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22 June 2017

issue

5901

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22 June 2017

page(s)

553-557

1 reference

The phi29 DNA polymerase:protein-primer structure suggests a model for the initiation to elongation transition

22 June 2017

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structural basis of transcription: an RNA polymerase II-TFIIB cocrystal at 4.5 Angstroms

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structure of a T7 RNA polymerase elongation complex at 2.9 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structural basis for the transition from initiation to elongation transcription in T7 RNA polymerase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structural basis of transcription initiation: RNA polymerase holoenzyme at 4 A resolution

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structure of a transcribing T7 RNA polymerase initiation complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structural basis for initiation of transcription from an RNA polymerase-promoter complex

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structural confirmation of a bent and open model for the initiation complex of T7 RNA polymerase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Transcription initiation in a single-subunit RNA polymerase proceeds through DNA scrunching and rotation of the N-terminal subdomains.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

The transition to an elongation complex by T7 RNA polymerase is a multistep process

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Twisted or shifted? Fluorescence measurements of late intermediates in transcription initiation by T7 RNA polymerase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Probing conformational changes in T7 RNA polymerase during initiation and termination by using engineered disulfide linkages

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

A mutation in T7 RNA polymerase that facilitates promoter clearance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structure and mechanism of the RNA polymerase II transcription machinery

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

The structural basis of the transition from initiation to elongation phases of transcription, as well as translocation and strand separation, by T7 RNA polymerase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

The initiation-elongation transition: lateral mobility of RNA in RNA polymerase II complexes is greatly reduced at +8/+9 and absent by +23.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Bacterial RNA polymerases: the wholo story

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

T7 promoter release mediated by DNA scrunching

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

The specificity loop of T7 RNA polymerase interacts first with the promoter and then with the elongating transcript, suggesting a mechanism for promoter clearance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Studies of contacts between T7 RNA polymerase and its promoter reveal features in common with multisubunit RNA polymerases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Interactions of the RNA polymerase of bacteriophage T7 with its promoter during binding and initiation of transcription

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Processivity in early stages of transcription by T7 RNA polymerase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Functional architecture of T7 RNA polymerase transcription complexes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Enzymatic properties of a proteolytically nicked RNA polymerase of bacteriophage T7.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Scanning mutagenesis reveals roles for helix n of the bacteriophage T7 RNA polymerase thumb subdomain in transcription complex stability, pausing, and termination

19 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1163433

Characterization of halted T7 RNA polymerase elongation complexes reveals multiple factors that contribute to stability

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1163433

A mutant T7 RNA polymerase that is defective in RNA binding and blocked in the early stages of transcription

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1126%2FSCIENCE.1163433

Mapping the location of TFIIB within the RNA polymerase II transcription preinitiation complex: a model for the structure of the PIC.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Structural transitions mediating transcription initiation by T7 RNA polymerase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

T7 RNA polymerase interacts with its promoter from one side of the DNA helix

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2892258

Major conformational changes occur during the transition from an initiation complex to an elongation complex by T7 RNA polymerase

27 November 2018

1 reference

12 December 2020

Topological and conformational analysis of the initiation and elongation complex of t7 RNA polymerase suggests a new twist

1 reference

12 December 2020

Major conformational changes during T7RNAP transcription initiation coincide with, and are required for, promoter release

1 reference

12 December 2020

Sequential release of promoter contacts during transcription initiation to elongation transition

1 reference

12 December 2020

T7 RNA polymerase elongation complex structure and movement

1 reference

12 December 2020

Identifiers

DOI

10.1126/SCIENCE.1163433

1 reference

22 June 2017

0 references

0 references

1 reference