(Q27652700)

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Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors † ‡

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scholarly article

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Different Thermodynamic Binding Mechanisms and Peptide Fine Specificities Associated with a Panel of Structurally Similar High-Affinity T Cell Receptors † ‡ (English)

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Lindsay L Jones

object named as

Lindsay L Jones

1

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Alexander J. Bankovich

object named as

Alexander J Bankovich

3

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author name string

Leremy A Colf

2

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Jennifer D Stone

4

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Yi-Gui Gao

5

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Choi Mui Chan

6

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Raven H Huang

7

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K Christopher Garcia

8

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David M Kranz

9

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publication date

25 November 2008

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47

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47

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12398-408

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Distinct CDR3 conformations in TCRs determine the level of cross-reactivity for diverse antigens, but not the docking orientation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

The structural dynamics and energetics of an immunodominant T cell receptor are programmed by its Vbeta domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

How a single T cell receptor recognizes both self and foreign MHC

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

How much can a T-cell antigen receptor adapt to structurally distinct antigenic peptides?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

A T cell receptor flattens a bulged antigenic peptide presented by a major histocompatibility complex class I molecule

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

Evidence that structural rearrangements and/or flexibility during TCR binding can contribute to T cell activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

CDR3 loop flexibility contributes to the degeneracy of TCR recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

Structural basis of plasticity in T cell receptor recognition of a self peptide-MHC antigen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

Coot: model-building tools for molecular graphics

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

PHENIX: building new software for automated crystallographic structure determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

20 March 2017

How TCRs bind MHCs, peptides, and coreceptors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

7 April 2017

Conformational changes and flexibility in T-cell receptor recognition of peptide-MHC complexes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Kinetic evidence for a ligand-binding-induced conformational transition in the T cell receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Interface-disrupting amino acids establish specificity between T cell receptors and complexes of major histocompatibility complex and peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Engineering and characterization of a stabilized alpha1/alpha2 module of the class I major histocompatibility complex product Ld.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Disparate thermodynamics governing T cell receptor-MHC-I interactions implicate extrinsic factors in guiding MHC restriction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Directed evolution of human T cell receptor CDR2 residues by phage display dramatically enhances affinity for cognate peptide-MHC without increasing apparent cross-reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

How the T cell receptor sees antigen--a structural view

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

High-affinity, peptide-specific T cell receptors can be generated by mutations in CDR1, CDR2 or CDR3.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

T cell cross-reactivity and conformational changes during TCR engagement

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

TCRs with high affinity for foreign pMHC show self-reactivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

CD8(-) T cell transfectants that express a high affinity T cell receptor exhibit enhanced peptide-dependent activation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Kinetics and thermodynamics of T cell receptor- autoantigen interactions in murine experimental autoimmune encephalomyelitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Differences in antigen recognition and cytolytic activity of CD8(+) and CD8(-) T cells that express the same antigen-specific receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

In vitro evolution of a T cell receptor with high affinity for peptide/MHC.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Critical role for CD8 in T cell receptor binding and activation by peptide/major histocompatibility complex multimers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Thermodynamics of T cell receptor binding to peptide-MHC: evidence for a general mechanism of molecular scanning

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Alphabeta T cell receptor interactions with syngeneic and allogeneic ligands: affinity measurements and crystallization

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

High-affinity reactions between antigen-specific T-cell receptors and peptides associated with allogeneic and syngeneic major histocompatibility complex class I proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

Immunoprecipitation of cell surface structures of cloned cytotoxic T lymphocytes by clone-specific antisera

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

29 September 2017

High-level bacterial secretion of single-chain alphabeta T-cell receptors.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

27 November 2018

Unraveling a hotspot for TCR recognition on HLA-A2: evidence against the existence of peptide-independent TCR binding determinants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

27 November 2018

The CDR3 regions of an immunodominant T cell receptor dictate the 'energetic landscape' of peptide-MHC recognition

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

27 November 2018

Efficient T cell activation requires an optimal dwell-time of interaction between the TCR and the pMHC complex

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

27 November 2018

Directed evolution of a stable scaffold for T-cell receptor engineering.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2680728

27 November 2018

TCR binding to peptide-MHC stabilizes a flexible recognition interface

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Quantitative analysis of the contribution of TCR/pepMHC affinity and CD8 to T cell activation

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Distinct molecular mechanisms account for the specificity of two different T-cell receptors

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Two different T cell receptors use different thermodynamic strategies to recognize the same peptide/MHC ligand

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Processing of X-ray diffraction data collected in oscillation mode

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kinetics and affinity of reactions between an antigen-specific T cell receptor and peptide-MHC complexes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of CD8 in staphylococcal enterotoxin B-mediated lysis by cytotoxic T lymphocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A residue in the center of peptide QL9 affects binding to both Ld and the T cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Alanine scanning mutagenesis of an alphabeta T cell receptor: mapping the energy of antigen recognition

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A very high level of crossreactivity is an essential feature of the T-cell receptor

1 reference

https://pubmed.ncbi.nlm.nih.gov/18973345

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1021/BI801349G

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