(Q27653739)

English

Combined X-ray and NMR Analysis of the Stability of the Cyclotide Cystine Knot Fold That Underpins Its Insecticidal Activity and Potential Use as a Drug Scaffold

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scholarly article

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Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19211551%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold (English)

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21 January 2020

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molecular knots

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21 January 2020

Jennifer L. Martin

3

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21 January 2020

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21 January 2020

K. Johan Rosengren

9

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21 January 2020

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21 January 2020

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Per Claeson

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21 January 2020

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Shu-Hong Hu

2

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21 January 2020

Tove Sjögren

4

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21 January 2020

Janos Hajdu

5

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21 January 2020

Lars Bohlin

6

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21 January 2020

Jun Tang

10

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21 January 2020

Ning-Hua Tan

11

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21 January 2020

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10 February 2009

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21 January 2020

Journal of Biological Chemistry

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21 January 2020

284

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21 January 2020

16

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21 January 2020

10672-10683

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19211551%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

Divalent cation coordination and mode of membrane interaction in cyclotides: NMR spatial structure of ternary complex Kalata B7/Mn2+/DPC micelle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

A continent of plant defense peptide diversity: cyclotides in Australian Hybanthus (Violaceae)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Statistically significant dependence of the Xaa-Pro peptide bond conformation on secondary structure and amino acid sequence

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Solution structure of the cyclotide palicourein: implications for the development of a pharmaceutical framework

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Twists, knots, and rings in proteins. Structural definition of the cyclotide framework

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Refined structure and metal binding site of the kalata B1 peptide

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Spatial structure of zervamicin IIB bound to DPC micelles: implications for voltage-gating

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Biosynthesis and insecticidal properties of plant cyclotides: the cyclic knotted proteins from Oldenlandia affinis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Membrane binding motif of the P-type cardiotoxin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Plant cyclotides: A unique family of cyclic and knotted proteins that defines the cyclic cystine knot structural motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Solution structure by NMR of circulin A: a macrocyclic knotted peptide having anti-HIV activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

PROMOTIF--a program to identify and analyze structural motifs in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Elucidation of the primary and three-dimensional structure of the uterotonic polypeptide kalata B1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Likelihood-enhanced fast rotation functions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Pushing the boundaries of molecular replacement with maximum likelihood

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Torsion angle dynamics for NMR structure calculation with the new program DYANA

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

MOLMOL: a program for display and analysis of macromolecular structures

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Satisfying hydrogen bonding potential in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Solvent content of protein crystals

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Improved methods for building protein models in electron density maps and the location of errors in these models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

The cyclotides: novel macrocyclic peptides as scaffolds in drug design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Chemistry. Seamless proteins tie up their loose ends

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Anti-HIV cyclotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Discovery, structure and biological activities of the cyclotides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

20 March 2017

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

7 April 2017

Conformation of Polypeptides and Proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

7 April 2017

Alanine scanning mutagenesis of the prototypic cyclotide reveals a cluster of residues essential for bioactivity.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Plant cyclotides disrupt epithelial cells in the midgut of lepidopteran larvae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

The chemistry and biology of cyclotides.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

NMR as a tool for elucidating the structures of circular and knotted proteins.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

A novel suite of cyclotides from Viola odorata: sequence variation and the implications for structure, function and stability.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Conformation and mode of membrane interaction in cyclotides. Spatial structure of kalata B1 bound to a dodecylphosphocholine micelle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

The cyclotide family of circular miniproteins: nature's combinatorial peptide template.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Key role of glutamic acid for the cytotoxic activity of the cyclotide cycloviolacin O2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Tissue-specific expression of head-to-tail cyclized miniproteins in Violaceae and structure determination of the root cyclotide Viola hederacea root cyclotide1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Cytotoxic cyclotides from Viola tricolor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

A comparison of the self-association behavior of the plant cyclotides kalata B1 and kalata B2 via analytical ultracentrifugation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Disulfide mapping of the cyclotide kalata B1. Chemical proof of the cystic cystine knot motif.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Cyclotides: a novel type of cytotoxic agents

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Circular proteins--no end in sight

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

The cystine knot motif in toxins and implications for drug design.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Influence of non-bonded parameters on the quality of NMR structures: a new force field for NMR structure calculation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

An unusual structural motif of antimicrobial peptides containing end-to-end macrocycle and cystine-knot disulfides

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Seven novel macrocyclic polypeptides from Viola arvensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Cyclopsychotride A, a biologically active, 31-residue cyclic peptide isolated from Psychotria longipes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

29 September 2017

Kalata B8, a novel antiviral circular protein, exhibits conformational flexibility in the cystine knot motif

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

2 June 2018

Oxytocic principles of Oldenlandia affinis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

2 June 2018

Isolation, solution structure, and insecticidal activity of kalata B2, a circular protein with a twist: do Möbius strips exist in nature?

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

Thermal, chemical, and enzymatic stability of the cyclotide kalata B1: the importance of the cyclic cystine knot.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

Structural characterization of an unusually stable cyclic peptide, kalata B2 from Oldenlandia affinis.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

On the size of the active site in proteases. I. Papain

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

PROCHECK: a program to check the stereochemical quality of protein structures

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

Processing of a 22 kDa precursor protein to produce the circular protein tricyclon A.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

Isolation and characterization of novel cyclotides from Viola hederaceae: solution structure and anti-HIV activity of vhl-1, a leaf-specific expressed cyclotide.

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

Primary and 3-D modelled structures of two cyclotides from Viola odorata

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M900021200

21 January 2018

Distribution and evolution of circular miniproteins in flowering plants

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2667754

27 November 2018

Studies on the membrane interactions of the cyclotides kalata B1 and kalata B6 on model membrane systems by surface plasmon resonance

1 reference

https://pubmed.ncbi.nlm.nih.gov/19211551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The role of the cyclic peptide backbone in the anti-HIV activity of the cyclotide kalata B1

1 reference

https://pubmed.ncbi.nlm.nih.gov/19211551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Amide proton temperature coefficients as hydrogen bond indicators in proteins

1 reference

https://pubmed.ncbi.nlm.nih.gov/19211551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

[The effect of surface active agents on Mycobacterium tuberculosis; tween 80]

1 reference

https://pubmed.ncbi.nlm.nih.gov/19211551

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1074/JBC.M900021200

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19211551%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19211551%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19211551%20AND%20SRC:MED&resulttype=core&format=json

21 January 2020

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