(Q27654785)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

title

The crystal structure of cobra venom factor, a cofactor for C3- and C5-convertase CVFBb (English)

1 reference

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26 January 2020

0 references

0 references

0 references

1

1 reference

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26 January 2020

author name string

Karthe Ponnuraj

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

Yuanyuan Xu

3

1 reference

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26 January 2020

Kevin Macon

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

John E Volanakis

5

1 reference

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26 January 2020

Sthanam V L Narayana

6

1 reference

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26 January 2020

publication date

1 April 2009

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26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

volume

17

1 reference

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26 January 2020

issue

4

1 reference

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26 January 2020

page(s)

611-619

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

Structure of and influence of a tick complement inhibitor on human complement component 5

26 January 2020

cites work

1 reference

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Structural basis for conserved complement factor-like function in the antimalarial protein TEP1.

20 March 2017

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Intrinsically unstructured proteins and their functions

20 March 2017

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Structure-guided identification of C3d residues essential for its binding to complement receptor 2 (CD21)

20 March 2017

1 reference

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Structural basis of collagen recognition by integrin alpha2beta1

20 March 2017

1 reference

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Crystal structure of the receptor-binding domain of alpha 2-macroglobulin

20 March 2017

1 reference

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Human complement C3b inactivator: isolation, characterization, and demonstration of an absolute requirement for the serum protein beta1H for cleavage of C3b and C4b in solution

20 March 2017

1 reference

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Likelihood-enhanced fast translation functions

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Likelihood-enhanced fast rotation functions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Pushing the boundaries of molecular replacement with maximum likelihood

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Structure of C3b reveals conformational changes that underlie complement activity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Structure of C3b in complex with CRIg gives insights into regulation of complement activation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

The structure of bovine complement component 3 reveals the basis for thioester function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Structures of complement component C3 provide insights into the function and evolution of immunity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

The cobra venom factor-dependent C3 convertase of human complement. A kinetic and thermodynamic analysis of a protease acting on its natural high molecular weight substrate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

The activation of human complement component C5 by a fluid phase C5 convertase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Isolation and characterization of a membrane protein from rat erythrocytes which inhibits lysis by the membrane attack complex of rat complement

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Alternative pathway of complement: recruitment of precursor properdin by the labile C3/C5 convertase and the potentiation of the pathway

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

C3 requirements for formation of alternative pathway C5 convertase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Multiparametric scaling of diffraction intensities

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Complement therapeutics; history and current progress.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Structural biology of the alternative pathway convertase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Complement C4bC2 complex formation: an investigation by surface plasmon resonance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Two clusters of acidic amino acids near the NH2 terminus of complement component C4 alpha'-chain are important for C2 binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Identification of the C3b binding site in a recombinant vWF-A domain of complement factor B by surface-enhanced laser desorption-ionisation affinity mass spectrometry and homology modelling: implications for the activity of factor B.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Mutations of the type A domain of complement factor B that promote high-affinity C3b-binding.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Molecular cloning and derived primary structure of cobra venom factor

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Analysis of the Short Consensus Repeats of Human Complement Factor B by Site-directed Mutagenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Induction of immune cytolysis: tumor-cell killing by complement is initiated by covalent complex of monoclonal antibody and stable C3/C5 convertase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Cobra venom factor and human C3 share carbohydrate antigenic determinants

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Site-directed mutagenesis of the region around Cys-241 of complement component C2. Evidence for a C4b binding site.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Complement C3: A molecular mosaic of binding sites

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Modulation of the alternative complement pathways by beta 1 H globulin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Cobra Venom Factor: Evidence for Its Being Altered Cobra C3 (the Third Component of Complement)

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

The influence of C3b inactivator (KAF) concentration on the ability of serum to support complement activation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Interactions of human complement component C3 with factor B and with complement receptors type 1 (CR1, CD35) and type 3 (CR3, CD11b/CD18) involve an acidic sequence at the N-terminus of C3 alpha'-chain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Isolation and characterization of a 33,000-dalton fragment of complement Factor B with catalytic and C3b binding activity.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Cobra venom factor: improved method for purification and biochemical characterization.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

The C3 convertase of the alternative pathway of human complement. Enzymic properties of the bimolecular proteinase

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

A novel cleavage product of human complement component C3 with structural and functional properties of cobra venom factor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Structure of the major oligosaccharide of cobra venom factor

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

A new function of the activated third component of complement: binding to C5, an essential step for C5 activation

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Engineering of human complement component C3 for catalytic inhibition of complement.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Small molecule integrin antagonists that bind to the beta2 subunit I-like domain and activate signals in one direction and block them in the other

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Inhibition of complement activation by recombinant Sh-CRIT-ed1 analogues

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

N-linked oligosaccharides of cobra venom factor contain novel alpha(1-3)galactosylated Le(x) structures

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Immunoreactivity and function of oligosaccharides in cobra venom factor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Comparison of Naja n. naja and Naja h. haje cobra-venom factors: correlation between binding affinity for the fifth component of complement and mediation of its cleavage.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Lung injury caused by cobra venom factor is reduced in rats raised on an essential fatty acid-deficient diet

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2671072

Common binding region of complement factors B, H and CR1 on C3b revealed by monoclonal anti-C3d

27 November 2018

1 reference

12 December 2020

Complement and neutrophil-mediated injury of perfused rat lungs

1 reference

12 December 2020

Each of the three binding sites on complement factor H interacts with a distinct site on C3b

1 reference

12 December 2020

Proteolytic activity of the different fragments of factor B on the third component of complement (C3). Involvement of the N-terminal domain of Bb in magnesium binding

1 reference

12 December 2020

Contribution of the complement control protein modules of C2 in C4b binding assessed by analysis of C2/factor B chimeras

1 reference

12 December 2020

Complement C2 receptor inhibitor trispanning and the beta-chain of C4 share a binding site for complement C2

1 reference

12 December 2020

Structural studies on the cobra venom factor: isolation, purification, crystallization and preliminary crystallographic analysis

1 reference

12 December 2020

Segment spanning residues 727-768 of the complement C3 sequence contains a neoantigenic site and accommodates the binding of CR1, factor H, and factor B

1 reference

12 December 2020

Cobra venom factor: structural homology with the third component of human complement

1 reference

12 December 2020

A discontinuous factor H binding site in the third component of complement as delineated by synthetic peptides

1 reference

12 December 2020

Carbohydrate composition of the second, third and fifth components and factors B and D of human complement

1 reference

12 December 2020

10.1016/J.STR.2009.01.015

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19368894%20AND%20SRC:MED&resulttype=core&format=json

26 January 2020

PubMed publication ID

19368894

1 reference