(Q27657615)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

title

An allosteric transition trapped in an intermediate state of a new kinesin-inhibitor complex (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

Venkatasubramanian Ulaganathan

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

Frank Kozielski

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

author name string

Hung Yi Kristal Kaan

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

David D Hackney

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

language of work or name

English

0 references

publication date

14 December 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

volume

425

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

issue

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

page(s)

55-60

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo

8 February 2020

cites work

1 reference

Small molecule inhibitor of mitotic spindle bipolarity identified in a phenotype-based screen

21 April 2017

1 reference

Crystal structure of the mitotic spindle kinesin Eg5 reveals a novel conformation of the neck-linker

21 April 2017

1 reference

Inhibition of a mitotic motor protein: where, how, and conformational consequences

21 April 2017

1 reference

Crystal structure of the kinesin motor domain reveals a structural similarity to myosin

21 April 2017

1 reference

Structure of human Eg5 in complex with a new monastrol-based inhibitor bound in the R configuration

21 April 2017

1 reference

The CCP4 suite: programs for protein crystallography

21 April 2017

1 reference

Refinement of macromolecular structures by the maximum-likelihood method

21 April 2017

1 reference

Coot: model-building tools for molecular graphics

21 April 2017

1 reference

PRODRG: a tool for high-throughput crystallography of protein-ligand complexes

21 April 2017

1 reference

Mitotic spindle organization by a plus-end-directed microtubule motor

21 April 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

A structural change in the kinesin motor protein that drives motility

21 April 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

S-trityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression.

21 April 2017

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

A structural model for monastrol inhibition of dimeric kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

A pathway of structural changes produced by monastrol binding to Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

Geometry of nonbonded interactions involving planar groups in proteins

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

Identification of the protein binding region of S-trityl-L-cysteine, a new potent inhibitor of the mitotic kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

Interaction of the mitotic inhibitor monastrol with human kinesin Eg5.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

A statistic for local intensity differences: robustness to anisotropy and pseudo-centering and utility for detecting twinning.

21 January 2018

1 reference

https://api.crossref.org/works/10.1042%2FBJ20091207

21 January 2018

Identifiers

DOI

10.1042/BJ20091207

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19793049%20AND%20SRC:MED&resulttype=core&format=json

8 February 2020

1 reference