(Q27658146)

Ajit Jadhav

4

0 references

James H McKerrow

11

James H McKerrow

0 references

Christopher P Austin

13

Christopher P Austin

0 references

Anton Simeonov

3

Anton Simeonov

0 references

Craig J. Thomas

Craig J Thomas

14

1 reference

ORCID Public Data File 2021

Brian K. Shoichet

15

Brian K Shoichet

0 references

author name string

Rafaela S Ferreira

2

0 references

Kenny Kean-Hooi Ang

5

0 references

William Leister

6

0 references

Min Shen

7

0 references

Julia T Silveira

8

0 references

Patricia S Doyle

9

0 references

Michelle R Arkin

10

0 references

James Inglese

12

0 references

David J Maloney

Journal of Medicinal Chemistry

16

0 references

language of work or name

English

0 references

publication date

14 January 2010

0 references

published in

0 references

volume

53

0 references

issue

1

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page(s)

52-60

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cites work

Compound Management for Quantitative High-Throughput Screening

1 reference

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A cysteine protease inhibitor cures Chagas' disease in an immunodeficient-mouse model of infection

20 March 2017

1 reference

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Crystal structures of reversible ketone-Based inhibitors of the cysteine protease cruzain

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

20 March 2017

1 reference

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Likelihood-enhanced fast translation functions

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

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Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

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Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol protease

20 March 2017

1 reference

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Rational modification of a candidate cancer drug for use against Chagas disease

29 September 2017

1 reference

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RNA interference of Trypanosoma brucei cathepsin B and L affects disease progression in a mouse model

29 September 2017

1 reference

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Identification of a new class of nonpeptidic inhibitors of cruzain

29 September 2017

1 reference

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Development of potent purine-derived nitrile inhibitors of the trypanosomal protease TbcatB.

29 September 2017

1 reference

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Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

A cysteine protease inhibitor protects dogs from cardiac damage during infection by Trypanosoma cruzi.

29 September 2017

1 reference

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NIH Molecular Libraries Initiative

29 September 2017

1 reference

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A cathepsin B-like protease is required for host protein degradation in Trypanosoma brucei

29 September 2017

1 reference

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A Common Mechanism Underlying Promiscuous Inhibitors from Virtual and High-Throughput Screening

29 September 2017

1 reference

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Potent second generation vinyl sulfonamide inhibitors of the trypanosomal cysteine protease cruzain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

Development of cysteine protease inhibitors as chemotherapy for parasitic diseases: insights on safety, target validation, and mechanism of action

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

Contribution of the glutamine 19 side chain to transition-state stabilization in the oxyanion hole of papain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

Novel purine nitrile derived inhibitors of the cysteine protease cathepsin K.

29 September 2017

1 reference

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In vitro evaluation of the disposition of A novel cysteine protease inhibitor.

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

Production of crystallizable cruzain, the major cysteine protease from Trypanosoma cruzi

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2804034

A generally applicable method for assessing the electrophilicity and reactivity of diverse nitrile-containing compounds

27 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19908842