(Q27658273)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

title

Gaining ligand selectivity in thyroid hormone receptors via entropy (English)

1 reference

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12 February 2020

1

1 reference

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12 February 2020

Alessandro S. Nascimento

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Ana Carolina M Figueira

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Munir Skaf

14

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Igor Polikarpov

15

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

13

Paul Webb

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

author name string

Fabio M Nunes

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Kevin Phillips

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Ricardo Aparicio

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Sandra Martha G Dias

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Jean H Lin

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Phuong Nguyen

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

James W Apriletti

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

Francisco A R Neves

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

John D Baxter

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

language of work or name

English

0 references

publication date

19 November 2009

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

number of pages

6

1 reference

Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

volume

106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

issue

49

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

page(s)

20717-20722

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

Structural basis of GC-1 selectivity for thyroid hormone receptor isoforms

12 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Thyroxine-thyroid hormone receptor interactions

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Ligand selectivity by seeking hydrophobicity in thyroid hormone receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Thyroid receptor ligands. 1. Agonist ligands selective for the thyroid receptor beta1

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

The entropic penalty of ordered water accounts for weaker binding of the antibiotic novobiocin to a resistant mutant of DNA gyrase: a thermodynamic and crystallographic study

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

All-atom empirical potential for molecular modeling and dynamics studies of proteins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Scalable molecular dynamics with NAMD

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Detection, delineation, measurement and display of cavities in macromolecular structures

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Physiological and molecular basis of thyroid hormone action

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Thermodynamic dissection of the binding energetics of KNI-272, a potent HIV-1 protease inhibitor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Thyroid hormone mimetics: potential applications in atherosclerosis, obesity and type 2 diabetes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Do enthalpy and entropy distinguish first in class from best in class?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

The thyroid hormone mimetic compound KB2115 lowers plasma LDL cholesterol and stimulates bile acid synthesis without cardiac effects in humans

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Detailed molecular understanding of agonistic and antagonistic vitamin D receptor ligands.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

The molecular mechanism of nitrogen-containing bisphosphonates as antiosteoporosis drugs

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Vitamin D receptor agonists specifically modulate the volume of the ligand-binding pocket

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Role of protein flexibility in ion permeation: a case study in gramicidin A.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Molecular dynamics simulations reveal multiple pathways of ligand dissociation from thyroid hormone receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Molecular dynamics simulations of biomolecules

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Evaluating conformational free energies: the colony energy and its application to the problem of loop prediction

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Selective modulation of thyroid hormone receptor action.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Hormone selectivity in thyroid hormone receptors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Novel ligands that function as selective estrogens or antiestrogens for estrogen receptor-alpha or estrogen receptor-beta

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Unbinding of retinoic acid from its receptor studied by steered molecular dynamics

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Augmented hepatic and skeletal thyromimetic effects of tiratricol in comparison with levothyroxine.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Just add water! The effect of water on the specificity of protein-ligand binding sites and its potential application to drug design

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

A structural role for hormone in the thyroid hormone receptor.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2791634

Molecular dynamics simulations of ligand dissociation from thyroid hormone receptors: evidence of the likeliest escape pathway and its implications for the design of novel ligands

2 June 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911024106

Only subtle protein conformational adaptations are required for ligand binding to thyroid hormone receptors: simulations using a novel multipoint steered molecular dynamics approach.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911024106

Selectivity principle of the ligand escape process from a two-gate tunnel in myoglobin: molecular dynamics simulation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911024106

Structural evaluation of the agonistic action of a vitamin D analog with two side chains binding to the nuclear vitamin D receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911024106

Rearrangements in thyroid hormone receptor charge clusters that stabilize bound 3,5',5-triiodo-L-thyronine and inhibit homodimer formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911024106

PACKMOL: a package for building initial configurations for molecular dynamics simulations.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0911024106

Structural rearrangements in the thyroid hormone receptor hinge domain and their putative role in the receptor function

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19926848

12 December 2020

inferred from PubMed ID database lookup

Stabilization of Proteins by Ligand Binding: Application to Drug Screening and Determination of Unfolding Energetics

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19926848

12 December 2020

inferred from PubMed ID database lookup

Probing a Water Channel near the A-Ring of Receptor-Bound 1α,25-Dihydroxyvitamin D3 with Selected 2α-Substituted Analogues†

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19926848

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1073/PNAS.0911024106

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19926848%20AND%20SRC:MED&resulttype=core&format=json

12 February 2020

PubMed publication ID

19926848

1 reference