(Q27660385)

2

0 references

Ines Kaupe

4

0 references

Florian Grebien

3

0 references

John Wojcik

1

0 references

Shohei Koide

object named as

Shohei Koide

10

0 references

Keiryn L Bennett

5

object named as

Keiryn L Bennett

0 references

author name string

John Barkinge

6

0 references

Richard B Jones

7

0 references

Akiko Koide

Nature Structural & Molecular Biology

8

0 references

publication date

April 2010

0 references

published in

0 references

volume

17

0 references

issue

4

0 references

page(s)

519-27

0 references

cites work

The selectivity of receptor tyrosine kinase signaling is controlled by a secondary SH2 domain binding site

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Charting the molecular network of the drug target Bcr-Abl

20 March 2017

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Structural coupling of SH2-kinase domains links Fes and Abl substrate recognition and kinase activation

20 March 2017

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A Dominant Conformational Role for Amino Acid Diversity in Minimalist Protein–Protein Interfaces

20 March 2017

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Structure, dynamics, and binding thermodynamics of the v-Src SH2 domain: implications for drug design

20 March 2017

1 reference

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Grb7 SH2 domain structure and interactions with a cyclic peptide inhibitor of cancer cell migration and proliferation

20 March 2017

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High-throughput generation of synthetic antibodies from highly functional minimalist phage-displayed libraries

20 March 2017

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Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening

20 March 2017

1 reference

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High-affinity single-domain binding proteins with a binary-code interface

20 March 2017

1 reference

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Large-scale mapping of human protein-protein interactions by mass spectrometry

20 March 2017

1 reference

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A quantitative protein interaction network for the ErbB receptors using protein microarrays

20 March 2017

1 reference

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Towards a proteome-scale map of the human protein–protein interaction network

20 March 2017

1 reference

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Interchangeable functions of Arabidopsis PIROGI and the human WAVE complex subunit SRA1 during leaf epidermal development

20 March 2017

1 reference

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Structural basis for the autoinhibition of c-Abl tyrosine kinase

20 March 2017

1 reference

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Probing protein conformational changes in living cells by using designer binding proteins: application to the estrogen receptor

20 March 2017

1 reference

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Crystal structures of the XLP protein SAP reveal a class of SH2 domains with extended, phosphotyrosine-independent sequence recognition

20 March 2017

1 reference

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Binding of a high affinity phosphotyrosyl peptide to the Src SH2 domain: crystal structures of the complexed and peptide-free forms

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Recognition of a high-affinity phosphotyrosyl peptide by the Src homology-2 domain of p56lck

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Shape complementarity at protein/protein interfaces

20 March 2017

1 reference

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Assembly of Cell Regulatory Systems Through Protein Interaction Domains

20 March 2017

1 reference

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High-throughput phosphotyrosine profiling using SH2 domains

20 March 2017

1 reference

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Multiple stimuli induce tyrosine phosphorylation of the Crk-binding sites of paxillin

20 March 2017

1 reference

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Evidence that SH2 domains promote processive phosphorylation by protein-tyrosine kinases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

The chemokine interleukin-8 and the surface activation protein CD69 are markers for Bcr-Abl activity in chronic myeloid leukemia.

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Binding specificity of SH2 domains: insight from free energy simulations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Picomolar affinity fibronectin domains engineered utilizing loop length diversity, recursive mutagenesis, and loop shuffling

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

In vivo selection of intrabodies specifically targeting protein-protein interactions: a general platform for an "undruggable" class of disease targets

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Recognizing and exploiting differences between RNAi and small-molecule inhibitors

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Mass spectrometry-based functional proteomics: from molecular machines to protein networks

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Processive phosphorylation: mechanism and biological importance

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Monobodies: antibody mimics based on the scaffold of the fibronectin type III domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Phosphoinositide, phosphopeptide and pyridone interactions of the Abl SH2 domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Organization of the SH3-SH2 unit in active and inactive forms of the c-Abl tyrosine kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Tyrosine plays a dominant functional role in the paratope of a synthetic antibody derived from a four amino acid code

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

HCaRG increases renal cell migration by a TGF-alpha autocrine loop mechanism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Molecular recognition by a binary code

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

The SH2 domain: versatile signaling module and pharmaceutical target

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Peptide aptamers: specific inhibitors of protein function

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Regulation of the c-Abl and Bcr-Abl tyrosine kinases

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

A myristoyl/phosphotyrosine switch regulates c-Abl

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Antagonists of the Src homology 2 (SH2) domains of Grb2, Src, Lck and ZAP-70.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

SH2 domain inhibition: a problem solved?

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Searching for specificity in SH domains

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Signal transducer and activator of transcription (STAT)5 activation by BCR/ABL is dependent on intact Src homology (SH)3 and SH2 domains of BCR/ABL and is required for leukemogenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

The fibronectin type III domain as a scaffold for novel binding proteins

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Transformation of hematopoietic cells by BCR/ABL requires activation of a PI-3k/Akt-dependent pathway.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

BCR-ABL-induced oncogenesis is mediated by direct interaction with the SH2 domain of the GRB-2 adaptor protein

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Point mutations in the abl SH2 domain coordinately impair phosphotyrosine binding in vitro and transforming activity in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

STAT5 signaling is required for the efficient induction and maintenance of CML in mice

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Induction of chronic myelogenous leukemia in mice by the P210bcr/abl gene of the Philadelphia chromosome

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Bruton's tyrosine kinase is not essential for Bcr-Abl-mediated transformation of lymphoid or myeloid cells

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Diversity in the SH2 domain family phosphotyrosyl peptide binding site

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

High-affinity Src-SH2 ligands which do not activate Tyr(527)-phosphorylated Src in an experimental in vivo system

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Investigation of phosphotyrosine recognition by the SH2 domain of the Src kinase

27 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2926940

Monoclonal antibody successes in the clinic

27 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.1793

Three-dimensional solution structure of the src homology 2 domain of c-abl

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.1793

Highly potent inhibitors of the Grb2-SH2 domain

31 March 2020

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNSMB.1793

31 March 2020

Identifiers

DOI

10.1038/NSMB.1793

1 reference

Dimensions Publication ID

4661394

1004045087

0 references

Fatcat ID

release_dsvgzwmpkzbzzn2don6pehxw4y

0 references

4661394

1 reference

1 reference

1 reference