(Q27667409)

18

0 references

Rasheduzzaman Chowdhury

1

0 references

Christopher J. Schofield

17

0 references

Eleanor A L Bagg

Eleanor A Bagg

5

0 references

Oliver King

Oliver N King

12

0 references

Nathan R Rose

Nathan R Rose

6

0 references

Michael A McDonough

Michael A McDonough

11

0 references

Peter J. Ratcliffe

Peter J Ratcliffe

16

0 references

Ya-Min Tian

3

Ya-Min Tian

0 references

Ian J Clifton

13

Ian J Clifton

0 references

Rob Klose

14

Robert J Klose

0 references

Timothy D W Claridge

15

Timothy D W Claridge

0 references

Kar Kheng Yeoh

2

Kar Kheng Yeoh

0 references

Lars Hillringhaus

4

Lars Hillringhaus

0 references

Ivanhoe K. H. Leung

7

Ivanhoe K H Leung

0 references

Esther C Y Woon

9

Esther C Y Woon

0 references

author name string

Xuan S Li

8

0 references

Ming Yang

Quantitative High-Throughput Screening Identifies 8-Hydroxyquinolines as Cell-Active Histone Demethylase Inhibitors

10

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publication date

May 2011

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published in

EMBO Reports

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volume

12

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page(s)

463-9

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issue

5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Structural basis for binding of cyclic 2-oxoglutarate analogues to factor-inhibiting hypoxia-inducible factor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

The common feature of leukemia-associated IDH1 and IDH2 mutations is a neomorphic enzyme activity converting alpha-ketoglutarate to 2-hydroxyglutarate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Structural basis for binding of hypoxia-inducible factor to the oxygen-sensing prolyl hydroxylases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Inhibitor scaffolds for 2-oxoglutarate-dependent histone lysine demethylases

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Structural and mechanistic studies on the inhibition of the hypoxia-inducible transcription factor hydroxylases by tricarboxylic acid cycle intermediates

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Structure of factor-inhibiting hypoxia-inducible factor (HIF) reveals mechanism of oxidative modification of HIF-1 alpha

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Kinetic and crystallographic studies on deacetoxycephalosporin C synthase (DAOCS)

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Systematic sequencing of renal carcinoma reveals inactivation of histone modifying genes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Glioma-derived mutations in IDH1 dominantly inhibit IDH1 catalytic activity and induce HIF-1alpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Oxygen sensing by metazoans: the central role of the HIF hydroxylase pathway

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Histone lysine methylation and demethylation pathways in cancer

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

IDH mutations in glioma and acute myeloid leukemia

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Kinetic studies of Escherichia coli AlkB using a new fluorescence-based assay for DNA demethylation

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

JHDM1B/FBXL10 is a nucleolar protein that represses transcription of ribosomal RNA genes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Structural insights into histone demethylation by JMJD2 family members.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

D-2-Hydroxyglutaric aciduria: unravelling the biochemical pathway and the genetic defect

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

Cancer-associated metabolite 2-hydroxyglutarate accumulates in acute myelogenous leukemia with isocitrate dehydrogenase 1 and 2 mutations

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3090014

SDH5 mutations and familial paraganglioma: somewhere Warburg is smiling

2 June 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.43

Q&A: Cancer: clues from cell metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.43

Monoclonal antibody-based screening assay for factor inhibiting hypoxia-inducible factor inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.43

2-oxoglutarate analogue inhibitors of HIF prolyl hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.43

The selectivity and inhibition of AlkB.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FEMBOR.2011.43

21 January 2018

Identifiers

DOI

10.1038/EMBOR.2011.43

1 reference

1103158

1103158

1 reference

1 reference

1 reference