(Q27670703)

Iain W McNae

Linda A Fothergill-Gilmore

2

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7

Linda A Fothergill-Gilmore

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Douglas S Auld

6

Douglas S Auld

0 references

Wenhe Zhong

4

Wenhe Zhong

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author name string

Hugh P Morgan

1

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Matthew W Nowicki

3

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Paul A M Michels

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

9 September 2011

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published in

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volume

286

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issue

36

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page(s)

31232-40

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cites work

An improved strategy for the crystallization ofLeishmania mexicanapyruvate kinase

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Allosteric Mechanism of Pyruvate Kinase from Leishmania mexicana Uses a Rock and Lock Model

20 March 2017

1 reference

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Sulphate removal induces a major conformational change in Leishmania mexicana pyruvate kinase in the crystalline state

20 March 2017

1 reference

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Structure and function of human erythrocyte pyruvate kinase. Molecular basis of nonspherocytic hemolytic anemia

20 March 2017

1 reference

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The structure of pyruvate kinase from Leishmania mexicana reveals details of the allosteric transition and unusual effector specificity

20 March 2017

1 reference

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Structure of the bis(Mg2+)-ATP-oxalate complex of the rabbit muscle pyruvate kinase at 2.1 A resolution: ATP binding over a barrel

20 March 2017

1 reference

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Phasercrystallographic software

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Scaling and assessment of data quality

20 March 2017

1 reference

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Coot: model-building tools for molecular graphics

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Refinement of macromolecular structures by the maximum-likelihood method

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

A graphical user interface to the CCP4 program suite

20 March 2017

1 reference

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Structural basis for tumor pyruvate kinase M2 allosteric regulation and catalysis

20 March 2017

1 reference

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Effects of suramin, an anti-human immunodeficiency virus reverse transcriptase agent, on protein kinase C. Differential activation and inhibition of protein kinase C isozymes

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Cytosolic phosphorylation potential

20 March 2017

1 reference

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The CCP4 molecular-graphics project

20 March 2017

1 reference

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EDULISS: a small-molecule database with data-mining and pharmacophore searching capabilities

7 April 2017

1 reference

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Evaluation of thieno[3,2-b]pyrrole[3,2-d]pyridazinones as activators of the tumor cell specific M2 isoform of pyruvate kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Evaluation of substituted N,N'-diarylsulfonamides as activators of the tumor cell specific M2 isoform of pyruvate kinase

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

IC50-to-Ki: a web-based tool for converting IC50 to Ki values for inhibitors of enzyme activity and ligand binding

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Antiviral drug discovery: ten more compounds, and ten more stories (part B).

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Suramin: clinical uses and structure-activity relationships.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Experimental and in silico analyses of glycolytic flux control in bloodstream form Trypanosoma brucei

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

The adenosine analog tubercidin inhibits glycolysis in Trypanosoma brucei as revealed by an RNA interference library

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

The putative effector-binding site of Leishmania mexicana pyruvate kinase studied by site-directed mutagenesis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Suramin blocks nucleotide triphosphate binding to ribosomal protein L3 from Trypanoplasma borreli

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Suramin enters and accumulates in low pH intracellular compartments of v-sis-transformed NIH 3T3 cells

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Recent research on the biological activity of suramin

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Pyruvate kinase of Leishmania mexicana mexicana. Cloning and analysis of the gene, overexpression in Escherichia coli and characterization of the enzyme.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Dye-ligand affinity chromatography: the interaction of Cibacron Blue F3GA with proteins and enzymes.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Suramin protection of T cells in vitro against infectivity and cytopathic effect of HTLV-III.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Compartmentation of carbohydrate metabolism in trypanosomes

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Suramin, a novel antitumor compound.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

In vivo regulation of monomer-tetramer conversion of pyruvate kinase subtype M2 by glucose is mediated via fructose 1,6-bisphosphate

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Double role for pyruvate kinase type M2 in the expansion of phosphometabolite pools found in tumor cells.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

A pilot study of suramin in the treatment of progressive refractory follicular lymphomas

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Suramin: With Special Reference to Onchocerciasis

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Uptake of the trypanocidal drug suramin by bloodstream forms of Trypanosoma brucei and its effect on respiration and growth rate in vivo

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

The phosphoglycerate kinases from Trypanosoma brucei. A comparison of the glycosomal and the cytosolic isoenzymes and their sensitivity towards suramin.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Effects of various metabolic conditions and of the trivalent arsenical melarsen oxide on the intracellular levels of fructose 2,6-bisphosphate and of glycolytic intermediates in Trypanosoma brucei.

2 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3173065

Experimental and computational approaches to estimate solubility and permeability in drug discovery and development settings

2 June 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.212613

Suramin-induced reciprocal changes in glucose and lactate synthesis in renal tubules contribute to its hyperglycaemic action

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.212613

Evidence for a non-LDL-mediated entry route for the trypanocidal drug suramin in Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.212613

Synthesis and activity of inhibitors highly specific for the glycolytic enzymes from Trypanosoma brucei

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M110.212613

Suramin and suramin analogs activate skeletal muscle ryanodine receptor via a calmodulin binding site

21 January 2018

1 reference

12 December 2020

Effect of suramin on the human pathogen Candida albicans: implications on the fungal development and virulence

1 reference

12 December 2020

Intramitochondrial and Extramitochondrial Concentrations of Adenine Nucleotides and Inorganic Phosphate in Isolated Hepatocytes from Fasted Rats

1 reference

12 December 2020

Suramin analogues as subtype-selective G protein inhibitors

1 reference

12 December 2020

Identifiers

DOI

10.1074/JBC.M110.212613

1 reference

release_i5oq3wqgfzgjpgotnnl3r3chuq

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

21733839

1 reference