(Q27671815)

1

object named as

Scott J Lusher

0 references

Ross McGuire

object named as

Ross McGuire

10

0 references

Koen J Dechering

4

object named as

Koen Dechering

0 references

author name string

Scott J Lusher

1

0 references

Hans C A Raaijmakers

2

0 references

Diep Vu-Pham

3

0 references

Tsang Wai Lam

5

0 references

Angus R Brown

6

0 references

Niall M Hamilton

7

0 references

Olaf Nimz

8

0 references

Rolien Bosch

9

0 references

Arthur Oubrie

11

0 references

Jacob de Vlieg

Journal of Biological Chemistry

12

0 references

language of work or name

English

0 references

publication date

7 October 2011

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published in

0 references

volume

286

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issue

40

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page(s)

35079-86

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cites work

Improving the developability profile of pyrrolidine progesterone receptor partial agonists

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Rational design of orally-active, pyrrolidine-based progesterone receptor partial agonists

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

The X-ray Structure of RU486 Bound to the Progesterone Receptor in a Destabilized Agonistic Conformation

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Met909 plays a key role in the activation of the progesterone receptor and also in the high potency of 13-ethyl progestins

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Structural basis of spirolactone recognition by the mineralocorticoid receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

A structural and in vitro characterization of asoprisnil: a selective progesterone receptor modulator

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Atomic structure of progesterone complexed with its receptor

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

A graphical user interface to the CCP4 program suite

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Asoprisnil (J867): a selective progesterone receptor modulator for gynecological therapy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Progesterone antagonists and progesterone receptor modulators: an overview

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Progesterone receptor modulators and progesterone antagonists in women's health

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Activating mineralocorticoid receptor mutation in hypertension exacerbated by pregnancy

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Nuclear-receptor ligands and ligand-binding domains

20 March 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

20 March 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

A new generation of progesterone receptor modulators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

International Union of Pharmacology. LXV. The pharmacology and classification of the nuclear receptor superfamily: glucocorticoid, mineralocorticoid, progesterone, and androgen receptors

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Selective progesterone receptor modulators and progesterone antagonists: mechanisms of action and clinical applications

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Nuclear receptor structure: implications for function

20 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

The evolution of progesterone receptor ligands.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Molecular and pharmacological properties of a potent and selective novel nonsteroidal progesterone receptor agonist tanaproget

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Discovery of non-steroidal mifepristone mimetics: pyrazoline-based PR antagonists

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Crystal structure of a mutant mineralocorticoid receptor responsible for hypertension.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Making optimal use of empirical energy functions: force-field parameterization in crystal space

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Structure and function of the glucocorticoid receptor ligand binding domain

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Transactivation functions of the N-terminal domains of nuclear hormone receptors: protein folding and coactivator interactions

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Nuclear receptor ligand-binding domains: three-dimensional structures, molecular interactions and pharmacological implications

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Ligand-protein interactions in nuclear receptors of hormones.

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Human progesterone receptor A and B isoforms in CHO cells. II. Comparison of binding, transactivation and ED50 values of several synthetic (anti)progestagens in vitro in CHO and MCF-7 cells and in vivo in rabbits and rats

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

Human progesterone receptor A and B isoforms in CHO cells. I. Stable transfection of receptor and receptor-responsive reporter genes: transcription modulation by (anti)progestagens

29 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3186393

The nuclear receptor ligand-binding domain: structure and function

29 September 2017

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.273029

Discovery of orally active, pyrrolidinone-based progesterone receptor partial agonists.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.273029

Progesterone receptor ligand binding pocket flexibility: crystal structures of the norethindrone and mometasone furoate complexes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.273029

A ligand-mediated hydrogen bond network required for the activation of the mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.273029

Structural and biochemical mechanisms for the specificity of hormone binding and coactivator assembly by mineralocorticoid receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M111.273029

The binding of progesterone, R-5020 and ORG-2058 to progesterone receptor

21 January 2018

1 reference

12 December 2020

Selective progesterone receptor modulators 1: use during pregnancy

1 reference

12 December 2020

Selective progesterone receptor modulators 2: use in reproductive medicine

1 reference

12 December 2020

Selective progesterone receptor modulators 3: use in oncology, endocrinology and psychiatry

1 reference

12 December 2020

Discovery and optimisation of a selective non-steroidal glucocorticoid receptor antagonist

1 reference

12 December 2020

Contraceptive progestins. Various 11-substituents combined with four 17-substituents: 17alpha-ethynyl, five- and six-membered spiromethylene ethers or six-membered spiromethylene lactones

1 reference

12 December 2020